Drug name
Brand Name:
ROUTE,
DOSAGE,
FREQUENCY
Route:
oral
Vastarel
Dosage:
Generic Name:
35 mg
Trimetazidine
Therapeutic Class:
Cardiac
Preparation
Pharmacologic
Class:
Antiemetic Agents;
Antihistamines, 1st
Generation;
Antihistamines,
Piperazine
Derivatives.
Frequency:
One tablet
twice daily,
that is once
in the
morning
and once in
the
evening,
during
meals.
MECHANISM
OF ACTION
Helps the
heart muscle
to switch
from using
energy from
fat to using
energy from
glucose,
helping the
heart muscle
to consume
less oxygen
and energy,
preventing
angina
pectoris.
INDICATION,
CONTRAINDICATION,
ADVERSE EFFECTS
Indication:
Trimetazidine is indicated in
adults as add-on therapy for
the symptomatic treatment of
patients with stable angina
pectoris who are inadequately
controlled by or intolerant to
first-line antianginal
therapies.
Contraindications:
Hypersensitivity to
Trimetazidine or to any of the
other ingredients of
Trimetazidine (Vastarel MR).
Parkinson disease,
parkinsonian symptoms,
tremors, restless leg
syndrome, and other related
movement disorders.
Severe renal impairment
(creatinine clearance
<30ml/min).
Adverse effects:
As with all medicines,
Trimetazidine (Vastarel MR) is
likely to have side effects,
although not everyone may
be prone to them.
NURSING
RESPONSIBILITY
Assess for
hypersensitivity
to
trimetazidine,
with heart
failure and
pregnancy
Administer
drug after
patient has
eaten with a
full glass of
water
Encourage
patient to
continue
efforts at
smoking
cessation
Provide safety
measures if
lethargy occurs