LEARNING OUTCOME • List the features of gas exchange surfaces in humans, limited to large surface area, thin surface, good blood supply and good ventilation with air • What makes the lungs an efficient gas exchange surface? 1. Made up of millions of alveoli (air sacs) that provide a large surface area 2. The wall of the alveoli and the blood capillary have thin surface as both are made up of only single layer of cells 3. There is a network of capillary under the alveoli that provides a good blood supply 4. Continuous breathing provides good ventilation (exchange) of air rich in oxygen and air rich in carbon dioxide LEARNING OUTCOME • Name and identify the internal and external intercostal muscles LEARNING OUTCOME • State the functions of the cartilage in the trachea Cartilage – present in the trachea and the bronchi Prevents these tubes from collapsing while exhaling (breathing out) LEARNING OUTCOME • Explain the role of the ribs, the internal and external intercostal muscles and the diaphragm in producing volume and pressure changes in the thorax leading to the ventilation of the lungs • Internal intercostal muscles contract while the external intercostal muscles relax • The ribcage contracts back and down • Diaphragm muscle relaxes and becomes dome shaped • Volume of the chest cavity decreases • Pressure increases • Air from the lungs at higher pressure is forced out to lower atmospheric pressure LEARNING OUTCOME • State the differences in composition between inspired and expired air, limited to oxygen, carbon dioxide and water vapour • Percentage of Nitrogen is the same in both inspired & expired air • Oxygen is more in the inspired air (21 – 16 = 5% more) • Carbon dioxide is more in the expired air (4 – 0.04 = 3.96%) • Explain the differences in composition between inspired and expired air LEARNING OUTCOME • Use limewater as a test for carbon dioxide to investigate the differences in composition between inspired and expired air • Carbon dioxide turns limewater, Ca(OH)2 milky or cloudy • We know, that expired air contains more carbon dioxide • Air is inhaled though flask A • Air is exhaled to flask B • Limewater in flask B turns cloudy faster • It is because exhaled air contains more carbon dioxide LEARNING OUTCOME • Explain the link between physical activity and rate and depth of breathing in terms of the increased carbon dioxide concentration in the blood, detected by the brain, causing an increased rate of breathing • During and after the exercise both the rate (number of breaths per minute) and the depth (how deep we breathe) increases Explanation • During exercise the muscles contract more so they require more energy • So the respiration rate increases in the muscles • More carbon dioxide is produced and diffuses into the blood • This makes the blood acidic (low pH, as CO2 is acidic) • This low pH is detected by the brain (hypothalamus) • So to bring the pH back to normal by removing carbon dioxide faster, the brain sends impulses to increase the rate of breathing LEARNING OUTCOME • Explain the role of goblet cells, mucus and ciliated cells in protecting the gas exchange system from pathogens and particles The inner walls of the trachea and the bronchi are lined (covered) by mucus, ciliated epithelial cells and goblet cells mucus – keeps the surface moist and traps the dust, pollen and pathogens that we may inhale Goblet cells – secretes slimy substance called mucus Ciliated epithelial cells – sweeps the mucus with the trapped substances out of the trachea into the food pipe (oesophagus)