Cell Membrane: - Maintains homeostasis by controlling what substance may enter or leave cells. Passive Transport: Substances crossing cell membrane without energy input by the cell, from high to low concentration. “Down” the concentration gradient 1) Diffusion (no facilitation) o o o o o o movement of molecules from high to low concentration concentration gradient: difference in concentration of molecules across a distance Driven by molecules’ kinetic energy Molecules in constant motion, move randomly, in straight line End result: causing the concentration of solution the same throughout the space = Equilibrium Random movement of molecules continues even in equilibrium Diffusion across membranes = simple diffusion - depends on size, type of molecules - depends on the chemical nature of the membrane - Phospho-lipid bilayer - certain proteins can form pores in the membranes (e.g. molecules can dissolve in lipids may pass directly thruCO2 and O2 are non-polar and can dissolve in lipids. (e.g. molecules that are very small, but not soluble in lipids may diffuse across the membrane by moving thru the poles in the membrane)