NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • • • • Lesson 19: Addiction What is a substance? Refers to any Drugs, Medication, or Toxins that share the potential for abuse. Substance use and substance-related disorders can involve alcohol, stimulants, cannabis, opioids, hallucinogens, inhalants, sedatives, hypnotics, and anxiolytics. Terminologies Polysubstance abuse - abuse of more than one substance Designer drugs - synthetic substances made by altering existing medications or formulating new substances not yet controlled or regulated by the FDA Intoxication - use of a substance that results in maladaptive behavior Withdrawal syndrome - the negative psychological and physical reactions that occur when the use of a substance ceases or dramatically decreases. Detoxification - the process of safely withdrawing from a substance. Substance Abuse - using a drug in a way that is inconsistent with medical or social norms and despite negative consequences. Substance dependence - includes problems associated with addiction such as tolerance, withdrawal, and unsuccessful attempts to stop using the substance. Onset and Clinical Course Alcohol is the substance abused most often. The early course of alcoholism typically begins much earlier, with the first episode of intoxication between 12-14 years of age. The first evidence of minor alcohol-related problems is seen in the late teens. Episodes of "sipping" alcohol may occur at age 8 years or even earlier. A pattern of more severe difficulties for people with alcoholism begins to emerge in the mid-20s to the mid-30s. These difficulties can be the alcohol-related breakup of a significant relationship, an arrest for public intoxication or driving while intoxicated, evidence of alcohol withdrawal, early alcohol-related health problems, or significant interference with functioning at work or school. During this time, the person experiences his or her first blackout, which is an episode during which the person continues to function but has no conscious awareness of his • • • • • • • • • • • or her behavior at the time or any later memory of the behavior. As the person continues to drink, he or she often develops a tolerance for alcohol; that is, he or she needs more alcohol to produce the same effect. After continued heavy drinking, the person experiences a tolerance break, which means that very small amounts of alcohol intoxicate the person. Related Disorders Gambling Disorder Is a non-substance related diagnosis. It is characterized by problem gambling, spending money one cannot afford to lose, lying about gambling, getting money from others and an inability to refrain from gambling for any specific of time. Attempts to quit or cut down result in restless, anxious, and irritable behavior. Caffeine, Tobacco, or Nicotine Are substances that are addictive and are included in the Diagnostic and Statistical Manual of Mental Disorders, but are not considered mental health problems per se. Addiction to Internet Noting that some people spend more than half of their waking hours on the computer, and become upset and irritable if use is limited or curtailed. Substance-Induced Anxiety Refers to the experience of anxiety symptoms that are caused by substance use or withdrawal Can be caused by a wide range of substances, including alcohol, caffeine, nicotine, cannabis, cocaine, amphetamines, and opioids. These substances can directly affect the brain's neurotransmitters, which can lead to the development of anxiety symptoms. Withdrawal from these substances can also trigger anxiety symptoms, as the brain struggles to readjust to normal functioning without the substance. Substance-Induced Psychosis A type of psychotic disorder that can occur as a result of substance use or withdrawal. It is a serious mental health condition that can be difficult to treat and may have lasting consequences. ALAS, BACO, BALLESCAS, OGA, PUNZALAN 1 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • Can be caused by a wide range of substances, including cannabis, cocaine, amphetamines, hallucinogens, and alcohol. They can interfere with the brain's neurotransmitters, leading to changes in mood, perception, and behavior. Withdrawal from these substances can also trigger psychosis, as the brain struggles to readjust to normal functioning without the substance. Etiology The exact causes of drug use, dependence, and addiction are unknown, but various factors are thought to contribute to the development of substance-related disorders (Boland and Verduin, 2022) Much of the research on biologic and genetic factors has been done on alcohol abuse, but psychological, social, environmental studies have examined other drugs as well. Biological Factors Genetic Research has shown that there is a strong heritability component to addiction, with genetic factors accounting for up to 50% of an individual's vulnerability to addiction. Various genes have been implicated in addiction, including those that regulate the brain's reward system, stress response, and impulse control. For example: children of alcoholic parents are at higher risk for developing alcoholism and drug dependence than are children of non-alcoholic parents. Neurochemical Influences Neurotransmitters such as dopamine, serotonin, and norepinephrine play a critical role in addiction. These chemicals are involved in regulating the brain's reward system, which is activated when we engage in pleasurable activities such as eating, having sex, or using drugs. Addictive substances hijack the brain's reward system by causing a surge of dopamine, which leads to feelings of pleasure and reinforces the behavior. Over time, the brain becomes less sensitive to the effects of dopamine, and individuals may require larger amounts of the substance to achieve the same high. Changes in other neurotransmitters, such as glutamate and GABA, have also been implicated in addiction. • • • • • • • • • • • • Brain Structure Brain imaging studies have shown that addiction is associated with structural and functional changes in various regions of the brain, including the prefrontal cortex, amygdala, and striatum. These changes can affect decision-making, impulse control, and emotional regulation, making it more challenging for individuals to quit using drugs or engaging in addictive behaviors. For example, chronic drug use has been shown to lead to a decrease in gray matter volume in the prefrontal cortex, which is responsible for executive function. Psychological Factors Personality Traits Research has shown that certain personality traits can increase an individual's risk of developing addiction. For example, individuals who are sensationseeking, impulsive, or have low self-esteem are more likely to develop addiction. People who have difficulty coping with stress and negative emotions may also be more vulnerable to addiction. Individuals who have a history of trauma or abuse may be at increased risk of developing addiction as a way to cope with emotional pain. Cognitive Processes Cognitive processes, such as decision-making, attention, and learning, play an important role in addiction. Individuals with addiction may have cognitive biases that influence their decision-making, such as a focus on short-term rewards and a tendency to discount the potential negative consequences of their behavior. They may also have difficulty learning from negative experiences, leading to continued substance use or engagement in addictive behaviors. Individuals with addiction may have impaired attention and impulse control, which can make it difficult to resist cravings and avoid triggers. Motivations Motivations for substance use and addictive behaviors can vary widely. For some individuals, addiction may be a way to cope with stress or negative emotions, while for others, it may be a way to seek pleasure or enhance social connections. Some individuals ALAS, BACO, BALLESCAS, OGA, PUNZALAN 2 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • • may use substances or engage in addictive behaviors to manage physical pain or other symptoms of mental health conditions. Understanding an individual's motivations for addiction is essential in developing effective treatment strategies. • Social and Environmental Factors Social Factors Social factors, such as peer pressure, social norms, and cultural attitudes, can significantly impact an individual's risk of developing addiction. For example, individuals who have friends or family members who use drugs or engage in addictive behaviors are more likely to develop addiction themselves. Cultural attitudes towards substance use and addiction can impact an individual's willingness to seek help for their addiction and can influence the availability of resources for treatment. • Environmental Factors Environmental factors, such as access to drugs or addictive behaviors, can also play a significant role in addiction vulnerability. Individuals who live in areas with high rates of drug use or who have easy access to drugs are more likely to develop addiction. Individuals who experience high levels of stress or trauma may be more vulnerable to addiction as a way to cope with these experiences. Environmental factors such as poverty, homelessness, and lack of access to healthcare can also contribute to addiction vulnerability. Family Dynamics Family dynamics can also play a significant role in addiction vulnerability. Individuals who grow up in homes with parents or siblings who use drugs or engage in addictive behaviors are more likely to develop addiction themselves. Individuals who experience neglect, abuse, or other adverse childhood experiences may be more vulnerable to addiction as a way to cope with these experiences. Peer Pressure Peer pressure can also be a significant factor in addiction vulnerability. Individuals who feel pressure from their peers to use drugs or engage in addictive behaviors may be more likely to do so themselves. • • • • • • • • • • • This can be particularly true for adolescents and young adults who are still developing their sense of identity and may feel a need to conform to peer expectations. Cultural Consideration Cultural Attitudes Cultural attitudes towards substance use and addiction can impact an individual's willingness to seek help for their addiction and can influence the availability of resources for treatment. For example, in some cultures, addiction may be stigmatized or viewed as a moral failing rather than a disease. This can make it difficult for individuals to seek help for their addiction or to receive appropriate treatment. Cultural attitudes towards specific substances or behaviors may impact an individual's risk of developing addiction Cultural Values Cultural values can also impact an individual's risk of developing addiction. For example, cultures that place a high value on conformity or social conformity may be more likely to have higher rates of addiction among individuals who feel pressure to conform to social expectations. Similarly, cultures that place a high value on individualism or personal autonomy may be more likely to have higher rates of addiction among individuals who prioritize their own desires over social norms. Cultural Beliefs and Practices Cultural beliefs and practices can also impact an individual's risk of developing addiction. For example, some cultures may have traditional practices involving the use of certain substances or addictive behaviors. These practices may be seen as socially acceptable or even encouraged within the culture. Additionally, some cultures may have traditional healing practices that involve the use of psychoactive substances. These practices can impact an individual's attitudes towards substance use and addiction. Access to Resources Access to resources for prevention and treatment can also be impacted by cultural factors. ALAS, BACO, BALLESCAS, OGA, PUNZALAN 3 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • In some cultures, there may be a lack of resources for addiction treatment, or the resources that are available may not be culturally appropriate or sensitive to the needs of the community. Additionally, cultural factors may impact an individual's willingness to seek help or to participate in treatment programs. Types of Substance and Treatment These are mood-altering substances that have similarities and differences depending on its intended effect, intoxication effects, and withdrawal symptoms. However, treatment approaches after detoxification are quite similar. Alcohol A Central Nervous System Depressant that is absorbed rapidly into the bloodstream. Intoxication and Overdose Initial effects of alcohol intake include: o Relaxation o Loss of inhibitions Effects during Intoxication: o Slurred speech o Unsteady gait o Lack of coordination o Impaired attention, concentration, memory, and judgment. o Aggressiveness o Display inappropriate sexual behavior. o May also experience blackout Overdose is an excessive alcohol intake for a short period of time. Effects include: o Vomiting o Unconsciousness o Respiratory depression ▪ Combination of these 3 may cause Aspiration Pneumonia or Pulmonary Obstruction. o Alcohol-induced Hypotension ▪ May lead to Cardiovascular shock and death. Treatment The goal of the treatment is to remove the substance and support respiratory and cardiovascular function. Administration of Central Nervous System stimulants is contraindicated. Gastric lavage and dialysis Long-Term Physiological Effects of Alcohol Use • Cardiac Myopathy • Wernicke Encephalopathy • Korsakoff Psychosis • Pancreatitis • Esophagitis • Hepatitis • Cirrhosis • Leukopenia • Thrombocytopenia • Ascites • • • • • • • • • • Withdrawal Symptoms of withdrawal begin 4 to 12 hours after cessation or marked reduction of alcohol intake. Alcohol withdrawal usually peaks on the second day and is over in about 5 days; May also take 1 to 2 weeks. Symptoms include: o Coarse hand tremors o Sweating o Elevated pulse and blood pressure o Insomnia o Anxiety o Nausea or Vomiting Severe Withdrawal Symptom: o Transient Hallucinations o Seizures o Delirium Detoxification Alcohol withdrawal can be life-threatening, detoxification needs to be accomplished under medical supervision. If the client’s withdrawal symptoms are mild, and they can abstain from alcohol: o Can be treated safely at home. If the client’s withdrawal symptoms are mild, and cannot abstain from alcohol: o Short admission of 3 to 5 days. Pharmacologic management for safe withdrawal includes: o Benzodiazepines ▪ Lorazepam, Diazepam, and Chlordiazepoxide. Withdrawal can be accomplished by: o Fixed-scheduled dosing also known as Tapering o Symptom-triggered dosing Presence and severity of withdrawal symptoms determine the amount of medication needed and the frequency of the administration. ALAS, BACO, BALLESCAS, OGA, PUNZALAN 4 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • • • • • • Addiction Research Foundation Clinical Institute Withdrawal Assessment for Alcohol, Revised. (for the assessment tool, please refer to page 361 of the ninth edition of the book) The use of an assessment tool such as the Clinical Institute Withdrawal Assessment of Alcohol Scale. o Patients on symptom-triggered dosing receive medication based on this scale. o Patients on fixed-scheduled dosing receive additional doses based on this scale. A score of less than 8 indicates mild withdrawal. A score of 8 to 15 indicates moderate withdrawal. A score of 15 or above indicates severe withdrawal. • Sedatives, Hypnotics, and Anxiolytics Drugs that are Central Nervous System stimulants such as: o Barbiturates o Nonbarbiturate hypnotics o Anxiolytics, particularly benzodiazepines. Most frequently abused drugs: Barbiturates and Benzodiazepines. Effects of the drugs, intoxication, and withdrawal symptoms are similar to alcohol. Intended purpose: o Reduce anxiety, with drowsiness as a side effect. • Intoxication and Overdose Benzodiazepines when taken orally in overdose is rarely fatal. The effect however is that the person becomes lethargic and confused. Treatment includes gastric lavage followed by ingestion of activated charcoal and a saline cathartic. Dialysis can be used for severe symptoms. Symptoms improve as the drug is excreted. Barbiturates when taken in orally in overdose is fatal. Effects include: o Comatose o Respiratory arrest o Cardiac failure o Death • • • • • • • • • • Treatment in the ICU is required using gastric lavage or dialysis to remove the drug from the system and to support respiratory and cardiac function. Withdrawal Onset of withdrawal symptoms depends on the half-life of the drug. Benzodiazepines such as Lorazepam which typically lasts about 10 hours, produce withdrawal symptoms in 6 to 8 hours. Withdrawal syndrome is characterized by symptoms that are opposite of the acute effects of the drug – autonomic hyperactivity such as: o Elevated pulse, blood pressure, respiration, and temperature. o Hand tremor o Insomnia o Anxiety o Nausea o Psychomotor agitation Seizures and hallucinations occur rarely. Detoxification Detoxification is often medically managed by tapering the amount of the drug the client receives over a period of time. Tapering is essential for barbiturates to prevent coma and death that may occur if the drug is stopped abruptly. Stimulants These are drugs that stimulate or excite the Central Nervous System and have limited clinical use and a high potential for abuse. Amphetamines, in the past, were used by people who want to lose weight quickly or stay awake. Cocaine is illegal, has no clinical use in medicine, but is highly addictive and a popular recreational drug because of the intense and immediate feeling or euphoria it produces. Methamphetamines is highly addictive and causes psychotic disorder and brain damage Intoxication and Overdose Intoxication develops rapidly. Effects include: o High or euphoric feeling o Hyperactivity o Hypervigilance o Talkativeness o Anxiety o Grandiosity o Hallucinations ALAS, BACO, BALLESCAS, OGA, PUNZALAN 5 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • • • o Stereotypic or repetitive behavior o Anger and fighting o Impaired judgment Physiological effects include: o Tachycardia o Elevated blood pressure o Dilated pupils o Perspirations or chills o Nausea o Chest pain o Confusion o Cardiac dysrhythmias Overdose can result in seizure and comatose. Death used to be rare. However, deaths associated with these stimulants are increasing. Withdrawal and Detoxification Withdrawal occurs within a few hours to several days after cessation of the drug and is not lifethreatening. Marked dysphoria is the primary withdrawal symptom, associated with: o Fatigue o Vivid and unpleasant dreams o Insomnia or hypersomnia o Increased appetite o Psychomotor retardation or agitation Marked withdrawal symptoms are referred to as crashing; o The person may experience depressive symptoms such as suicidal ideation Stimulant withdrawal is not treated pharmacologically Cannabis Cannabis sativa is the hemp plant, and is wildly cultivated for its fiber used to make rope and cloth, and for oil from its seeds. It became widely known for its psychoactive resin. The resin contains 60 substances called cannabinoids. Delta-9-tetrahydrocannabinol is thought to be responsible for most of the psychoactive effects. Marijuana refers to the upper leaves, flowering tops, and stems. Hashish refers to the dried resinous exudate from the leaves of the female plant. Cannabis is often smoked and can be eaten. In the USA, many states may have legalized medical marijuana use, recreational use, both, or neither • • • • • • • • • • • • • Research has shown that it has short-term effects of lowering intraocular pressure, but is not approves for the treatment of glaucoma 2 cannabinoids, Dronabinol and Nabilone, have been approved for treating nausea and vomiting from cancer chemotherapy Cannabis-related drugs have shown promise in the control of seizures Intoxication and Overdose Cannabis begins to act less than 1 minute after inhalation. Peak effects usually occur in 20 to 30 minutes, and last at least 2 to 3 hours. Users report effects similar to alcohol: o High feeling o Lowered inhibitions o Relaxation o Euphoria o Increased appetite Intoxication effects include: o Impaired motor coordination o Impaired judgment and short-term memory o Distortions of time and perception o Anxiety, dysphoria, and social withdrawal may occur sometimes. Physiological effects include: o Conjunctival injection or bloodshot eyes o Dry mouth o Hypotension o Tachycardia Excessive use may cause: o Delirium o Cannabis-induced psychotic disorder o Both can be treated symptomatically Withdrawal and Detoxification No clinically significant withdrawal syndrome is identified. Although some users report: o Muscle aches o Sweating o Anxiety o Tremors Opioids These are popular drugs of abuse because they desensitize the user both physiological and psychological pain and induce a sense of euphoria and well-being. Opioid compounds include potent prescription analgesics and illegal substances. Potent prescription drugs include: ALAS, BACO, BALLESCAS, OGA, PUNZALAN 6 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • o Morphine o Meperidine o Codeine o Hydromorphone o Oxycodone o Methadone o Oxymorphone o Hydrocodone o Propoxyphene Illegal substances include: o Heroin o Illicitly produced fentanyl o Normethadone Fentanyl is a synthetic opioid used in clinical settings for anesthesia. It is 50 to 100 times more potent than morphine. Illicitly produced fentanyl is thought to be responsible for the dramatic increase in deaths from an opioid overdose. People who abuse opioids spend a great deal of time in obtaining the drug. Either by engaging in illegal activities. HCWs often write prescriptions for themselves or divert prescribed pain medications for clients to themselves. Intoxication and Overdose Opioid intoxication develops soon after the initial euphoric feeling. Symptoms include: o Apathy o Lethargy o Listlessness o Impaired judgment o Psychomotor retardation or agitation o Constricted pupils o Drowsiness o Slurred speech o Impaired attention and memory Opioid overdose can lead to: o Comatose o Respiratory depression o Pupillary constriction o Unconsciousness o Death Treatment includes the administration of Naloxone, an opioid antagonist, as it reverses all the signs of opioid toxicity. Naloxone is given every few hours until the opioid level drops to nontoxic. This process takes a few process Higher doses of Naloxone are needed today because of the synthetic opioid commonly used today. Withdrawal and Detoxification • • • • • • • • • • • • Opioid withdrawal develops when drug intake ceases or decreases markedly, or can be precipitated by the administration of opioid antagonists. Initial symptoms are: o Anxiety o Restlessness o Aching back and legs o Cravings for more opioids Symptoms may progress to: o Nausea and vomiting o Dysphoria o Lacrimation o Rhinorrhea o Sweating o Diarrhea o Yawning o Fever o Insomnia Symptoms of opioid withdrawal cause significant distress, but does not require pharmacologic management. Short acting drugs such as heroin produce withdrawal symptoms in 6 to 24 hours; peak in 2 to 3 days and gradually subsides in 5 to 7 days. Longer acting drug such as methadone may not produce significant withdrawal symptoms for 2 to 4 days, and symptoms may take 2 weeks to subside. Substitution of methadone during detoxification reduces symptoms to no worse than a mild case of flu. Withdrawal symptoms such as anxiety, insomnia, dysphoria, anhedonia, and drug craving may persist for weeks or months. Hallucinogens Substances that distort the user's perception of reality and produce symptoms similar to psychosis, including hallucinations (usually visual) and depersonalization. Can also cause increased pulse, blood pressure, and temperature; dilated pupils; and hyperreflexia. Examples include mescaline, psilocybin, lysergic acid diethylamide, and "designer drugs" such as ecstasy. Phencyclidine (PCP) is also included. Intoxication and Overdose Maladaptive behavioral or psychological changes: anxiety, depression, paranoid ideation, ideas of reference, fear of losing one’s ALAS, BACO, BALLESCAS, OGA, PUNZALAN 7 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • mind, and potentially dangerous behaviors such as jumping out a window in the belief that one can fly. Physiological symptoms: sweating, tachycardia, palpitations, blurred vision, tremors, and lack of coordination PCP intoxication often involves belligerence, aggression, impulsivity, and unpredictable behavior. Toxic reactions to hallucinogens (except PCP) are primarily psychological; overdoses as such do not occur. Psychotic reactions are managed best by isolation from external stimuli; physical restraints may be necessary for the safety of the client and others. PCP toxicity can include seizures, hypertension, hyperthermia, and respiratory depression. Medications are used to control seizures and blood pressure. Cooling devices such as hyperthermia blankets are used, and mechanical ventilation is used to support respirations. Withdrawal and Detoxification No withdrawal syndrome has been identified for hallucinogens, though some people have reported a craving for the drug. Hallucinogens can produce flashbacks, which are transient recurrences of perceptual disturbances like those experienced with hallucinogen use. These episodes occur even after all traces of the hallucinogen are gone and may persist for a few months up to 5 years. Inhalants A diverse group of drugs that include anesthetics, nitrates, and organic solvents that are inhaled for their effects. The most common substances are aliphatic and aromatic hydrocarbons found in gasoline, glue, paint thinner and spray paint. Less frequently used halogenated hydrocarbons include cleaners, correction fluids, spray can propellants, and other compounds containing esters, ketones, and glycols. Inhalants can cause significant brain damage, peripheral nervous system damage, and liver disease. Intoxification and Overdose Inhalant intoxication involves dizziness, nystagmus, lack of coordination, slurred • • • • • speech, unsteady gait, tremors, muscle weakness, and blurred vision. Stupor and coma can occur. Behavioral symptoms: belligerence, aggression, apathy, impaired judgment, and inability to function. Acute toxicity: anoxia, respiratory depression, vagal stimulation, and dysrhythmias. Death may occur from bronchospasm, cardiac arrest, suffocation, aspiration of the compound, or vomitus. Treatment consists of supporting respiratory and cardiac functioning until the substance is removed from the body. There are no antidotes or specific medications to treat inhalant toxicity. Withdrawal and Detoxification There are no withdrawal symptoms or detoxification procedures for inhalants as such, though frequent users report psychological cravings. People who abuse inhalants may suffer from persistent dementia or inhalantinduced disorders, such as psychosis, anxiety, or mood disorders even if the inhalant abuse ceases. These disorders are all treated symptomatically. Treatment and Prognosis • • • • • Today, treatment for substance use is available in a variety of community settings, not all of which involve health professionals Alcoholics Anonymous (AA) was founded in the 1930s by alcoholics. This self-help group developed the 12-step program model for recovery o Based on the philosophy that total abstinence is essential and that alcoholics need the help and support of others to maintain sobriety Many treatment programs, regardless of setting, use the 12-step approach and emphasize participation in AA. They also include individual counseling and a wide variety of groups. Clients being treated for intoxication and withdrawal or detoxification are encountered in a wide variety of medical settings from emergency departments to outpatient clinics. ALAS, BACO, BALLESCAS, OGA, PUNZALAN 8 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • If the client cannot remain sober during outpatient treatment, then inpatient treatment may be required. Acamprosate (Campral) Pharmacologic Treatment Drug Nursing Considerations Dosage Alcohol Withdrawal Drugs Lorazepam 2–4 mg every (Ativan) 2–4 hours PRN • • • Chlordiazepoxide (Librium) 50–100 mg, repeat in 2–4 hours if necessary; not to exceed 300 mg/day • • • Maintains abstinence from alcohol Disulfiram 500 mg/day • (Antabuse) for 1–2 weeks, then 250 mg/day Maintains abstinence from heroin Methadone Up to 120 • (Dolophine) mg/day for maintenance Maintains abstinence from opiates Levomethadyl 60–90 mg • (Orlaam) three times a week for maintenance Monitor VS Monitor effectiveness May cause dizziness or drowsiness Monitor VS Monitor effectiveness May cause dizziness or drowsiness Teach client to read labels to avoid products with alcohol May cause nausea and vomiting Do not take drug on consecutive days; take-home doses are not permitted Buprenorphine/ 4/1 mg–24/6 • May cause naloxone mg daily for orthostatic (Suboxone) maintenance hypotension, sedation • Avoid CNS depressants Blocks the effects of opiates; reduces alcohol cravings Naltrexone 350 • Client may not (ReVia, Trexan) mg/week, respond to divided into narcotics used three doses to treat cough, for opiatediarrhea, or blocking pain; effect; 50 • Take with food mg/day for up or milk to 12 weeks • May cause for alcohol headache, cravings restlessness, or irritability Suppresses opiate withdrawal symptoms Clonidine 0.1 mg every • Take blood (Catapres) 6 hours PRN pressure before each dose • Withhold if client is hypotensive Suppresses alcohol cravings • • • 666 mg three times daily • Monitor for diarrhea, vomiting, flatulence, and pruritis Vitamins and Supplements Thiamine 100 mg/day (vitamin B1) • Folic acid (folate) 1–2 mg/day • Cyanocobalamin (vitamin B12) 25–250 µg/day • Teach client about proper nutrition Teach client about proper nutrition Teach client about proper nutrition Dual Diagnosis The client with both substance abuse and another psychiatric illness is said to have a dual diagnosis. Dual diagnosis clients who have schizophrenia, schizoaffective disorder, or bipolar disorder present the greatest challenge to health care professionals. It is estimated that 50% of people with a substance abuse disorder also have mental health diagnoses. Traditional methods for treatment of major psychiatric illness or primary substance abuse often have limited success • • • • • • • • • Clients with a major psychiatric illness may have impaired abilities to process abstract concepts. Substance abuse has no limited recovery concept. The use of alcohol and other drugs can precipitate psychotic behavior Clients with a dual diagnosis (substance use and mental illness) present challenge that traditional settings cannot meet. Several key elements that need to be addressed include healthy, nurturing, supportive living environments Clients identified the need for stable housing, positive social support, using prayer or relying on a higher power, participation in meaningful activity, eating regularly, getting sufficient sleep, and looking presentable as important components of relapse prevention Application of the Nursing Process Assessment History General Appearance and Motor Behavior Mood and Affect ALAS, BACO, BALLESCAS, OGA, PUNZALAN 9 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • • • • ● • Thought Process and Content Sensorium and Intellectual Processes Judgment and Insight Self-Concept Roles and Relationships Physiological Considerations History Clients with a parent or other family members with substance abuse problems may report a chaotic family life, though this is not always the case Physical Problems or Development of Withdrawal Symptoms General Appearance and Motor Behavior Assessment of general appearance and behavior usually reveals appearance and speech to be normal. Clients may appear anxious, tired, and disheveled if they have just completed a difficult course of detoxification. Depending on their overall health status and any health problems resulting from substance use, clients may appear physically ill. Mood and Affect Wide ranges of mood and affect are possible. Some clients are sad and tearful, expressing guilt and remorse for their behavior and circumstances. Irritability is common because clients are newly free of substances. Thought Process and Content Clients are likely to minimize their substance use, blame others for their problems, and rationalize their behavior. Focus their attention on finances, legal issues, or employment problems as the main source of difficulty rather than their substance use. Sensorium and Intellectual Processes Clients generally are oriented and alert unless they are experiencing lingering effects of withdrawal. • • • • Self-Concept Clients generally have low self-esteem, which they may express directly or cover with grandiose behavior. They do not feel adequate to cope with life and stress without the substance and are often uncomfortable around others when not using. Roles and Relationships • • • • • • • • • • • • • Judgment and Insight Clients are likely to have exercised poor judgment, especially while under the influence of the substance. Difficulty acknowledging their behavior while using or may not see loss of jobs or relationships as connected to the substance use. • • Clients usually have experienced many difficulties with social, family, and occupational roles. Absenteeism and poor work performance are common Relationships in the family are often strained. Clients may be angry with family members who were instrumental in bringing them to treatment or who threatened loss of a significant relationship. Physiological Considerations Many clients have histories of poor nutrition (using rather than eating) and sleep disturbances that persist beyond detoxification Liver damage, Hepatitis, HIV infection from drug use. Data Analysis Dysfunctional Family Processes: Alcoholism Imbalanced Nutrition: Less than body requirements. Ineffective Denial Ineffective Coping Outcome Identification The client will abstain from alcohol and drug use. The client will express feelings openly and directly. The client will verbalize acceptance of responsibility for his or her own behavior. The client will practice nonchemical alternatives to deal with stress or difficult situations. The client will practice nonchemical alternatives to deal with stress or difficult situations. Intervention Substance abuse is an illness. Dispel myths about substance abuse. ALAS, BACO, BALLESCAS, OGA, PUNZALAN 10 NCM 76. Psychiatric Nursing 2nd Semester, SY 2022-2023 • • • • • • • • • • • • Prescribed medication can be an abused substance. Abstinence from substances is not a matter of willpower. Feedback from family about relapse signs, for example, a return to previous maladaptive coping mechanisms, is vital. Any alcohol, whether beer, wine, or liquor, can be an abused substance. Addressing Family Issues ○ Alcoholism (and other substance abuse) is often called a family illness. ○ Codependence is a maladaptive coping pattern on the part of family members or others resulting from a prolonged relationship with the person who uses substances. Characteristics of Codependence Poor relationship skills Excessive anxiety Worry Compulsive behaviors Resistance to change. • • • • Set realistic goals such as staying sober today Evaluation The effectiveness of substance abuse treatment is based heavily on the client’s abstinence from substances. In addition, successful treatment should result in more stable role performance, improved interpersonal relationships, and increased satisfaction with quality of life. Promoting Coping Skills The nurse can help clients focus on the present, not the past. It is not helpful for clients to dwell on past problems and regrets. The nurse can encourage clients to set attainable goals such as, “What can I do today to stay sober?” instead of feeling overwhelmed by thinking “How can I avoid substances for the rest of my life?” Clients need to believe that they can succeed. Characteristics of Codependence Codependent Behavior: Enabling Codependent behaviors have also been identified in health care professionals when they make excuses for a client’s behavior or do things for clients that clients can do for themselves. Addressing Family Issues Children of alcoholics: ○ Inability to trust ○ An extreme need to control, ○ An excessive sense of responsibility, and denial of feelings; these characteristics persist into adulthood. Without support and help to understand and cope, many family members may develop substance abuse problems of their own, thus perpetuating the dysfunctional cycle • • • • • • • Nursing Interventions Health teaching for the client and family Dispel myths surrounding substance abuse Decrease codependent behaviors among family members Make appropriate referrals for family members Promote coping skills Role-play potentially difficult situations Focus on the here-and-now with clients ALAS, BACO, BALLESCAS, OGA, PUNZALAN 11