LESSON PLAN – GENERAL BIOLOGY 2 CLASS DATE: April 04, April 06, & April 08, 2022 CLASS: STEM 1201 & STEM 1202 – 10:00AM TO 12:00NN – Monday STEM 1207 & STEM 1208 – 7:45AM TO 9:45AM – Wednesday STEM 1203 & STEM 1204 – 10:00AM TO 12:00NN – Wednesday STEM 1205 & STEM 1206 – 10:00AM TO 12:00NN – Friday I. LEARNING CONTENT SUBJECT: TOPIC: REFERENCE: ALLOTED TIME: General Biology 2 Molecular Structure of DNA, RNA, and Protein BCPSHS – LMS Week 8 General Biology 2, YouTube, Biomanbio.com 2 Hours II. LEARNING OBJECTIVES: 1. 2. 3. At the end of the lesson, the students should be able to: Differentiate DNA and RNA structure Describe transcription and translation in Protein synthesis Discuss the importance of the proteins in growth and development each of human being. III. LEARNING PROCEDURE A. Classroom Daily Routine: (5 minutes) Prayer Greetings Checking of Attendance B. Recall: (15 minutes) To recall the previous topic, the teacher will ask the following questions: 1. Who are the people behind the discovery of DNA Structure? 2. What are the 3 compositions of a nucleotides? 3. What are the nitrogenous bases of DNA? RNA? 4. What are the enzymes involved in the DNA replication? C. Motivation: (15 minutes) Find the pairs of each word on the flip box. Game title: Matching Pair Activity Source: https://wordwall.net/resource/11116363/science/protein-synthesis-labeling D. Discussion: ACTIVITY (40 minutes) Activity 1 - Video Analysis: DNA vs RNA Students must fill the table below after watching the video Video Title: Source: DNA vs. RNA - 5 Differences Between DNA and RNA https://www.youtube.com/watch?v=ruUf7ntRCk8 Sugar structure DNA Double strand Larger – millions of nucleotides Deoxyribose sugar Location Inside the nucleus Nitrogenous bases A, G, C, T (No Uracil) Structure Size RNA Single strand Shorter – thousands of nucleotides only Ribose sugar Outside the nucleus or in the ribosomes A, G, C, U (No Thymine) Activity 2.1 – Video Analysis: Protein synthesis Watch the video about protein synthesis and let students answers the following questions. Video Title: Source: Protein Synthesis https://www.youtube.com/watch?v=2zAGAmTkZNY Activity 2.2 - Simulation Game Activity: Do the simulation activity and let the students describe transcription and translation processes of protein synthesis on that activity. Activity Title: Source: Protein Synthesis Race https://biomanbio.com/HTML5GamesandLabs/LifeChemgames /protsynthracehtml5page.html ANALYSIS (20 minutes) 1. What is protein synthesis? -it is a process in which cells make proteins 2. What are the 2 stages or steps of protein synthesis? -Stage 1: Transcription, Stage 2: Translation 3. Where do transcription process happens? How about translation process? -Transcription: Nucleus, Translation: Cytoplasm (Ribosomes) 4. What are the 3 types of RNA involved protein synthesis? What are their roles? -mRNA (messenger RNA): carries genetic code from DNA in a nucleus to ribosome -rRNA (ribosomal RNA): form the core of a cell's ribosomes. The site of protein-making process. -tRNA (transfer RNA): it matches an mRNA codon with the amino acid it codes for. 5. What is a Codon? Anticodon? - A codon is a trinucleotide sequence of DNA or RNA nucleotides that corresponds with a specific amino acid while anticodon is also a trinucleotide sequence complementary to a corresponding codon in mRNA. ABSTRACTION (25 minutes) Game Activity: Label the Protein synthesis diagram Source: https://wordwall.net/resource/11116363/science/protein-synthesis-labeling APPLICATION (5 minutes) Why our body need proteins? Every cell in the human body contains protein. The basic structure of protein is a chain of amino acids. You need protein in your diet to help your body repair cells and make new ones. Protein is also important for growth and development in children, teens, and pregnant women. What will happen in our body if we lack protein? Serious protein deficiency can cause swelling, fatty liver, skin degeneration, increase the severity of infections and stunt growth in children. Kwashiorkor, also known as “edematous malnutrition” because of its association with edema (fluid retention), is a nutritional disorder most often seen in regions experiencing famine. It is a form of malnutrition caused by a lack of protein in the diet. IV. LEARNING ASSESSMENT Answer the following Activity on BCPSHS – LMS Analysis, Application, and Exploration Evaluation V. ASSIGNMENT Answer the Assignment Part of Week 8 on BCPSHS – LMS Prepared by: MGB General Biology Teacher