Principles of Anatomy and Physiology Gerard Tortora and Bryan Derrickson Sixteenth Edition Chapter 3 The Cellular Level of Organization Protein Synthesis This slide deck contains animations. Please disable animations if they cause issues with your device. Copyright ©2021 John Wiley & Sons, Inc. Introduction The purpose of this chapter is to: 1. Introduce the parts of a cell 2. Discuss the importance of the plasma membrane 3. Discuss the components of the cytoplasm 4. Compare and contrast mitosis and meiosis 5. Understand the effects aging has on the cell Copyright ©2021 John Wiley & Sons, Inc. 2 Protein Synthesis Copyright ©2021 John Wiley & Sons, Inc. 3 Copyright ©2017 ©2021 John Wiley & Sons, Inc. 4 4 Gene Expression Copyright ©2021 John Wiley & Sons, Inc. 5 Protein Synthesis: Transcription Transcription occurs in the nucleus and is the process by which genetic information encoded in DNA is copied onto a strand of RNA to direct protein synthesis Copyright ©2021 John Wiley & Sons, Inc. 6 Steps in Transcription Transcription is catalyzed by RNA polymerase; it has 4 steps: 1. Messenger RNA (mRNA) directs protein synthesis 2. Ribosomal RNA (rRNA) joins with ribosomal proteins to make ribosomes 3. Transfer RNA (tRNA) binds to amino acid and holds it in place during translation Copyright ©2021 John Wiley & Sons, Inc. 7 Protein Synthesis: Translation Translation occurs outside the nucleus and is the process of reading the mRNA nucleotide sequence to determine the amino acid sequence of the newly formed protein Copyright ©2021 John Wiley & Sons, Inc. 8 Copyright ©2017 ©2021 John Wiley & Sons, Inc. 9 9 Protein Synthesis During Transcription Copyright ©2021 John Wiley & Sons, Inc. 10 Replication of DNA Copyright ©2021 John Wiley & Sons, Inc. 11 Copyright ©2017 ©2021 John Wiley & Sons, Inc. 1212 Protein Synthesis Interactions Animation: Protein Synthesis Copyright ©2021 John Wiley & Sons, Inc. 13 Copyright ©2017 ©2021 John Wiley & Sons, Inc. 1414 Copyright ©2017 John Wiley & Sons, Inc. Copyright ©2021 John Wiley & Sons, Inc. 15 ahanafy@gulfcoast.edu Copyright ©2021 John Wiley & Sons, Inc. 16 Copyright Copyright © 2021 John Wiley & Sons, Inc. All rights reserved. Reproduction or translation of this work beyond that permitted in Section 117 of the 1976 United States Copyright Act without the express written permission of the copyright owner is unlawful. Request for further information should be addressed to the Permissions Department, John Wiley & Sons, Inc. The purchaser may make back-up copies for his/her own use only and not for distribution or resale. The Publisher assumes no responsibility for errors, omissions, or damages caused by the use of these programs or from the use of the information contained herein. Copyright ©2021 John Wiley & Sons, Inc. 17