--OVERVIEW OF ANATOMY AND PHYSIOLOGY-- SKELETAL SYSTEM ANATOMY AND PHYSIOLOGY -The skeletal system supports the body and provides a framework that the skeletal muscles use to cause movement. ANATOMY: •The study of structure and shape of the body and body parts and their relationships to one another. • Gross anatomy vs microscopic anatomy • body structure • means to dissect PHYSIOLOGY: MUSCULAR SYSTEM •Study of how the body and its parts work or function - The muscular system, composed of skeletal muscles, provides mobility to the body. • processes, functions • systemic physiology •cellular physiology ORGAN SYSTEM OVERVIEW •The highest level of structural organization, the organismal level, is made up of 11 organ system. NERVOUS SYSTEM -The nervous system is the body’s fast-acting control system. INTEGUMENTARY SYSTEM -The integumentary system is the external covering of the body or the skin. ENDOCTRINE SYSTEM - The endocrine glands produce chemical molecules called hormones that regulate other structures/organs. CARBOAVASCULAR SYSTEM URINARY SYSTEM -The primary organs of the cardiovascular system are the heart and blood vessels. The heart acts as blood pump, propelling blood through the blood vessels to all body tissues. -The urinary system (often called the excretory system) removes the nitrogencontaining wastes from the blood and flushes from the in urine. body REPRODUCTIVE SYSTEM LYMPHATIC SYSTEM -The organs of the lymphatic system include the lymphatic vessels, lymph nodes, the spleen, and tonsils. -The reproductve system exst prmarily to produce offspring. RESPIRATORY SYSTEM -The primary function of the respiratory system s to keep the body constantly supplied with oxygen and to remove carbon dioxide. ANATOMICAL POSITION -The body is erect with the feet parallel and the arms hanging at the sides with the palms facing forward. DIGESTIVE SYSTEM -The role of the digestive system s to break down food and deliver the products to the blood for dispersal to the body cells. ANTERIOR BODY LANDMARKS • Abdominal – anterior body trunk inferior to ribs • Acromial – point of shoulder • Antecubital – anterior surface of the elbow • Axillary – armpit • Brachial – arm • Buccal – cheek area • Carpal – wrist • Cervical – neck region • Coxal – hip • Crural – leg • Digital – fingers, toes • Femoral – thigh • Fibular – lateral part of the leg • Inguinal – area where thigh meets body trunk; groin • Nasal – nose area • Oral – mouth • Orbital – eye area • Patellar – anterior knee • Pelvic – area overlying the pelvis anteriorly • Pubic – genital region • Sternal – breastbone area • Tarsal – ankle region • Thoracic – chest • Umbilical – navel BODY PLANES AND SECTIONS • Section – “cut” • When a section is made through the body wall or through an organ, it is made along an imaginary line called a plane. SAGITTAL SECTION POSTERIOR BODY LANDMARKS • Calcaneal – heel of foot • Cephalic – head • Deltoid – curve of shoulder formed by large deltoid muscle • Femoral – thigh • Gluteal – buttock • Lumbar – area of back between hips • Occipital – posterior surface of head • Olecranal – posterior surface of elbow • Popliteal – posterior knee area • Sacral – area between hips • Scapular – shoulder blade region • Sural – posterior surface of lower leg; the calf • Vertebral – area of spine • Plantar – sole of the foot - A sagittal section is a cut made along the lengthwise, or longitudinal, plane of the body, dividing the body into right and left part If the cut is made down the median plane of the body and the right and left parts are equal, it is called a midsagittal, or median section FRONTAL/CORONAL SECTION CENTRAL BODY CAVITY Frontal section is a cut made along a lengthwise plane that divides the body into anterior and posterior parts. Like the dorsal body cavity, the ventral cavity is subdivided. body Thoracic cavity – separated from the rest of the ventral cavity by a dome-shaped muscle called the diaphragm. It encloses the heart and the lungs. TRANSVERSE/CROSS SECTION -Transverse section is a cut made along a horizontal plane, dividing the body or organ into superior and inferior parts. BODY CAVITIES DORSAL BODY CAVITY The dorsal body cavity has two subdivisions: the cranial cavity is the space inside the bony skull, and the spinal cavity that extends from the cranial cavity and nearly to the end of the vertebral column. Abdominopelvic cavity – is subdivided into a superior abdominal cavity, containing the stomach, liver, and the intestines, and an inferior pelvic cavity, that houses the reproductive organs, bladder, and rectum. ABDOMINOPELVIC QUADRANTS AND REGIONS ABDOMINOPELVIC REGIONS • Umbilical region – centermost region, surrounding the umbilicus. • Epigastric region – superior to the umbilical region • Abdominopelvic regions • Hypogastric region – inferior to the umbilical region • Right and left iliac region – lateral to the hypogastric region. • Right and left lumbar region – lateral to the umbilical region. • Right and left hypochondriac region – lateral to the epigastric region. CHAPTER I: THE HUMAN ORGANISM PHYSIOLOGY: 1.1 ANATOMY AND PHYSIOLOGY -Study of how the body and its parts work or function. ANATOMY: -The study of structure and shape of the body and body parts and their relationships to one another. - body structure - means to dissect TYPES OF ANATOMY 1. Developmental studies the structural changes that occur between conception and adulthood. • Embryology a subspecialty of developmental anatomy, considers changes from conception to the end of the eighth week of development. • Cytology examines the structural features of cells • Histology examines tissues, which are composed of cells and the materials surrounding them. 2. 3. 4. 5. 6. Gross anatomy study of structures that can be examined without the aid of a microscope, can be approached either systemically or regionally. Systemic: a group of structures that have one or more common functions, such as the cardiovascular, nervous, respiratory, skeletal, or muscular systems. In systemic anatomy, the body is studied system by system. Regional the body is studied area by area. Within each region, such as the head, abdomen, or arm, all systems are studied simultaneously. The regional approach is taken in most graduate programs at medical and dental schools. Surface involves looking at the exterior of the body to visualize structures deeper inside the body. For example, the sternum (breastbone) and parts of the ribs can be seen and palpated (felt) on the front of the chest. Anatomical imaging: using technologies (x-rays, ultrasound, MRI) - often examines systems rather than regions because a particular function can involve portions of a system in more than one region. TYPES OF PHYSIOLOGY 1. Cell physiology examines the processes occurring in cells. 2. Systemic physiology considers the functions of organ systems. 3. Neurophysiology deals with the heart and blood vessels. 4.Exericise physiology focuses on the changes in function and structure caused by exercise. IMPORTANCE OF ANATOMY AND PHYSIOLOGY Understand how the body: -Responds to stimuli - Environmental changes - Environmental cues - Diseases - Injury - maintains stable, internal conditions despite continually changing environment 1.2 STRUCTURAL AND FUNCTIONAL ORGANIZATION Six levels from chemical to organism: 1. Chemical: -The chemical level involves interactions between atoms, which are tiny building blocks of matter - atoms, chemical bonds, molecules 2. Cell: - cells: basic units of life; Cells are the basic structural and functional units of plants and animals. - compartments and organelles - smallest unit capable of reproduction e.g., mitochondria, nucleus, ribosomes, cytoplasm 3. Tissues: - group of cells with similar structure and function plus extracellular substances they release. - There are only four distinct types of tissue in an adult human: Epithelial They form the covering of all body surfaces, line body cavities and hollow organs, and are the major tissue in glands. They perform a variety of functions that include protection, secretion, absorption, excretion, filtration, diffusion, and sensory reception. The four major classes of simple epithelium are: 1) simple squamous; 2) simple cuboidal; 3) simple columnar; and 4) pseudostratified. Connective supporting organs and cells, transporting nutrients and wastes, defending against pathogens, storing fat, and repairing damaged tissues. Connective tissue is composed primarily of an extracellular matrix and a limited number of cells. There are four classes of connective tissues: blood, cartilage, bones, and connective tissue proper. Muscular a specialized tissue in animals which applies forces to different parts of the body by contraction. It is made up of thin and elongated cells called muscle fibers. It controls the movement of an organism. The cytoplasm in the muscle fibers is called sarcoplasm. The three main types of muscle include skeletal, smooth and cardiac. Nervous found in the brain, spinal cord, and nerves. It is responsible for coordinating and controlling many body activities. It stimulates muscle contraction, creates an awareness of the environment, and plays a major role in emotions, memory, and reasoning. Brain, Spinal Cord, and nerves are composed of nervous tissue, they are specialized for being stimulated to transmit stimulus from one to another part of the body rapidly. 4. organs: - Units made of multiple tissues that perform an independent function -two or more tissue types acting together to perform function(s) - e.g., stomach, heart, liver, ovary, bladder, kidney 5. organ system: - group of organs contributing to some function e.g., digestive system, reproductive system, cardiovascular system 6. organism: - A single living thing made of multiple organ systems, organs, tissues and cells - All organ systems working together - Includes associated microorganisms such as intestinal bacteria 1.3 CHARACTERISTIC OF LIFE six essential characteristics of life: 1. Organization functional interrelationships between parts of an organism and how those parts interact to perform specific functions. 2. Metabolism sum of all chemical and physical changes sustaining an organism; ability to acquire and use energy in support of these changes. 3. Responsiveness is an organism’s ability to sense changes in its external or internal environment and adjust to those changes. 4. Growth refers to an increase in the size or number of cells, which produces an overall enlargement of all or part of an organism. An increase in the materials surrounding cells can also contribute to growth. 5. Development includes the changes an organism undergoes through time, beginning with fertilization and ending at death. The greatest developmental changes occur before birth, but many changes continue after birth, and some go on throughout life. Development usually involves growth, but it also involves differentiation and morphogenesis. • Differentiation involves changes in a cell’s structure and function from an immature, generalized state to a mature, specialized state. • Morphogenesis is the change in shape of tissues, organs, and the entire organism. 6. Reproduction is the formation of new cells or new organisms. Without reproduction of cells, growth and development are not possible. Without reproduction of organisms, species become extinct. 1.4 BIOMEDICAL RESEARCH The area of science is devoted to the study of the processes of life, the prevention and treatment of disease, and the genetic and environmental factors related to disease and health. set points for some variables can be temporarily adjusted depending on body activities, as needed: Purpose: looks for ways to prevent and treat diseases that cause illness and death in people and in animals. body temperature Example of biomedical study: growing embryos for IVF, 3D-printing a heart, or finding a new medicine to fight cancer. blood pressure Difference between medical and biomedical research: Medicine is about diagnosing diseases and treating patients, while biomedical science is about research for treatment. Both these fields are related to improving human life and saving humans from deadly diseases. However, the paths these fields take are different. 1.5 HOMEOSTATIS Homeostasis is the existence and maintenance of a relatively constant environment within the body. To achieve homeostasis, the body must actively regulate conditions that are constantly changing. variables: measures of body properties that may change in value Examples of variables: Body temperature Blood glucose levels Heart rate Blood cell counts Blood pressure Respiratory rate set point: normal, or average value of a variable. normal range: normal extent of increase or decrease around a set point. Example: over time, body temperature fluctuates around a set point of about 98.6o examples common cause of change fever heart rate, respiratory rate exercise ASSESS YOUR PROGRESS 1. How does the study of anatomy differ from the study of physiology? 2. What is studied in gross anatomy? In surface anatomy? 3. What type of physiology is employed when studying the endocrine system? 4. Why are anatomy and physiology normally studied together? 5. From simplest to complex, list and define the body’s six levels of organization. 6. What are the four basic types of tissues? 7. What are the six characteristics of living things? Briefly explain each. 8. How does differentiation differ from morphogenesis? 9. Why is it important to recognize that humans share many, but not all, characteristics with other animals?