CITY OF MALABON UNIVERSITY Maya-maya cor. Pampano St., Longos Malabon City Telephone Nos. 374-57-72/ 374-58-57 COLLEGE OF ARTS AND SCIENCES Course Title: GENERAL ORGANIC CHEMISTRY Corse Credit: Course Code: CHM111 Semester/A.Y.: 2023– 2024 Contact Week: (18) weeks Contact Hours: (3) hours per week/54 hours per semester Course Prerequisite: NONE (3) units Class Schedule Day Time Room Professor: Vision: College of Arts Sciences envisions building a socially responsible community of analytical thinkers and value-driven professionals encompassing the arts, social sciences, and humanities to rise above the present society’s challenges in the service of the Filipinos. Mission: College of Arts and Sciences of the City of Malabon University aims to serve as the center of education in imparting interdisciplinary knowledge and character formation to improve the quality of life of every Filipino. College Goals: The course's objective is to equip learners, who would be potential policymakers in the public, corporate, or not-for-profit sectors, with the skills necessary to make sound judgments while coping with public administration. The course examines how public administration design and organization, efficiency, and motivation link to community and growth in a wide range of political governments, administrative ideologies, and social values. C O U R S E D E S C R I P T I O N This course in Chemistry offers a brief review on basic general chemistry topics such as chemical bonding, bond polarity and acids and bases that will serve as students’ spring board to concentrate on nomenclature, properties, stereochemistry, preparation, and reaction mechanisms of organic molecules such as alkanes, alkenes, alkynes, alkyl halides, aromatic hydrocarbons and other functional groups. In addition, this is designed to develop laboratory skills and techniques in handling organic compounds from purification to classical analysis to address the need for the 21st century science process skills among students. This subject will serve as a tool to grasp the major concepts and develop flexibility in applying those concepts in many extensions and applications of organic chemistry. C O U R S E O B J E C T I V E S At the end of the semester, the students will be able to: • • • • • Describe molecules based on bonding, orbitals, geometry, polarity, and properties Apply proper nomenclature procedure in naming different organic compounds Describe organic compounds based on their respective structure, properties, functions and reactions Explain and integrate reaction mechanisms of organic compounds to biological systems Perform experiments in preparing, isolating, purifying and characterizing different organic compounds. S IG N A T O R IE S Recommending Approval: Dr. LUCILA B. BONDOC Dean, College of Arts and Sciences Vision: The City of Malabon University, home of the city scholars is envisioned to be the center of excellence which shall bridge the learners to attain a higher standard of living by providing a highly cognitive and value-laden education. Mission: The City of Malabon University shall develop holistic learners, competent work force and guide them to their journey to excellence, encourage involvement of the stakeholders to create a better synergy with the community. Objectives: 1. To provide professional instruction and training in the liberal arts, sciences, and technology including information technology. 2. To promote applied research, advance studies and progressive leadership in the stated fields. 3. To introduce curricular studies which will promote globally competitive professionals, managers, instructors, entrepreneurs and leaders. 4. To offer other programs in the social, cultural, and technological fields. APPROVED: GLEN DV. DE LEON, Ph.D., CPA Vice President for Academic Affairs Page | 1 MIDTERM COVERAGE COURSE OUTLINE FINALS COVERAGE Week 1 – Class Orientation Week 11 - Organic Halides Week 2 - Development of Organic Chemistry Week 12 - Alcohol and Phenols Week 3 - Theories of Chemical Bonding Week 13 - Ether and Epoxides, and Thiols and Sulfide Week 4 - Bond Polarity and Resonance Structure Week 14 – Amine Week 5 - Classes and Sources of Organic Compounds Week 15 - Aldehydes and Ketones: Nucleophilic Addition Reactions Week 6 - Functional Groups Week 7 - Physical and Chemical Behaviour of Organic Compounds Week 16 - Carboxylic Acids and Derivatives Week 8 - Alkanes: Structure and Reactivity Week 17 - Chemistry of esters, acid halides, anhydrides, amides, and nitrites Week 9 – Alkynes, Aromatic Compounds: Benzene Chemistry Week 18 – FINAL EXAMINATION Week 10 – MIDTERM EXAM TIME TABLE DESIRED LEARNING OUTCOMES 1ST 2nd – 5th Week TOPICS TEACHINGLEARNING ACTIVITIES & RESOURCES ASSESSMENT COURSE OVERVIEW AND CLASS ORIENTATION Trace the development of organic chemistry Describe the structure of organic compounds based on bonding, polarity, resonance and properties. Unit 1: Introduction to Organic chemistry Lectures Laboratory Formative assessments Multimedia Presentation Rubrics for review and summary paper A. Development of Organic Chemistry B. Theories of Chemical Bonding 1. Valence Bond Theory 2. Molecular Orbital theory C. Bond Polarity and Resonance Structure 1. Polar Bonds and electronegativity and dipole moments 2. Formal charges and resonance Review Paper on the multimedia presentation Summary Paper on Lecture Learnings Problem Sets Page | 2 D. Classes and Sources of Organic Compounds E. Functional Groups 6th – 9th Week Identify different hydrocarbons based on given structure Predict properties of hydrocarbons based on the structure Explain the mechanism in the reactions of hydrocarbons F. Physical and Chemical Behaviour of Organic Compounds Unit 2: Hydrocarbons Alkanes: Structure and Reactivity o Alkanes and Alkyl Groups: Isomers o Nomenclature of Alkanes o Properties of Alkanes o Conformations of Alkanes o Cycloalkanes o Reactions: Combustion and Halogenation Alkenes: Structure and Reactivity o Naming Alkenes o Types and Structure of Alkenes o Physical Properties o Naturally Occurring Alkenes o Preparation of Alkenes Alkynes o Electronic Structure of Alkynes o Naming Alkynes o Preparation of Alkynes o Reaction of Alkynes o Keto-enol Tautomerism and Hydration Aromatic Compounds: Benzene Chemistry o Structure of Benzene: Kekule Proposal o Naming Aromatic Compounds o Structure and Stability of Benzene o Electrophilic Aromatic Substitution Reactions Lectures Laboratory Review Paper on the multimedia presentation Multimedia Presentations Formative assessments Summary Paper on Lecture Learning Molecular Models Problem Sets MIDTERM EXAMINATION TIME TABLE 11th – 14th Week DESIRED LEARNING OUTCOMES Identify alcohol, ether, amine and alkyl halides based on given structure Predict properties of alcohol, ether, amine and alkyl halides based on the structure TOPICS Unit 3: Organic Compounds with Electronegative Atoms A. Organic Halides a. Properties b. Preparation of Alkyl Halides TEACHINGLEARNING ACTIVITIES & RESOURCES ASSESSMENT Lectures Laboratory Review Paper on the multimedia presentation Multimedia (Video) Presentation Summary Paper on Lecture Learnings Page | 3 Explain the mechanism in the reactions of alcohol, ether, amine and alkyl halides 15th – 19th Week Identify aldehydes, ketones, carboxylic acids, etc based on given structure Predict properties of aldehydes, ketones, carboxylic acids, etc based on the structure Explain the mechanism in the reactions of aldehydes, ketones, carboxylic acids, etc c. Reaction of Alkyl Halides Alcohol and Phenols a. Naming Alcohols and Phenols b. Properties of Alcohol and Phenols c. Preparation of Alcohol and Phenols C. Ether and Epoxides, and Thiols and Sulfide a. Structure, Properties and Sources of Ethers b. Williamson Ether Synthesis c. Reaction of Ethers: Acidic Cleavage and Claisen Rearrangement D. Amine a. Structure and Bonding of Amine b. Properties and Sources of Amine c. Reactions of Amines and Aryl amines Unit 4: Carbonyl Compounds A. Aldehydes and Ketones: Nucleophilic Addition Reactions a. Naming Aldehydes and Ketones b. Synthesis of Aldehydes and Ketones c. Nucleophilic Addition Reactions of Aldehydes and Ketones B. Carboxylic Acids and Derivatives a. Naming Carboxylic Acids and Derivatives b. Occurrence and Properties of Carboxylic acids c. Synthesis of Carboxylic Acids C. Chemistry of esters, acid halides, anhydrides, amides, and nitrites Problem Sets B. Lectures Laboratory Formative assessments Laboratory Journal & Reports Multimedia (Video) Presentation Formative assessments Rubric for review and summary paper Lab Activity: Preparation of Flavoring Agents, aspirin & Soaps FINAL EXAMINATION REFERENCES: McMurry, John (2012). Fundamental of Organic Chemistry 8th Edition. New Jersey: Thomson-Brooks/Cole Bettelheim, Frederic A. et. al. (2010). Introduction to General, Organic and Biochemistry 9 th Edition. Brooks/Cole, Belmont California Carey, F.A. and Giuliano, R.M. (2015). Organic Chemistry 9th Edition. McGraw-Hill International Morrison, R.T. and R.N. Boyd (1992). Organic Chemistry 6th Edition. New Jersey: Prentice Hall International Inc. Institutional Grading System All colleges and the School of Graduate Studies shall observe the institutional grading system to ensure uniformity in giving our students numerical grades. Page | 4 % Scale Rating 98-100 95-97 92-94 89-91 86-88 83-85 80-82 77-79 75-76 Below 75 Numerical Rating 1.00 1.25 1.50 1.75 2.00 2.25 2.50 2.75 3.00 5.00 INC DO DU (5.00) Remarks Excellent Excellent Very Good Very Good Good Good Satisfactory Satisfactory Passed Failed Incomplete Dropped Officially Dropped Unofficially Prepared by: RAMIL A. BAUTISTA Part time Professor Page | 5