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Bioethics research essay Draft

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Topic:
Plant transformation can achieve results that are impossible with conventional
breeding methods. Explain some of the advantages of using biotechnology
techniques and why there is a need for this in the world. Shortly explain the ethical
concerns of using genetically modified plants.

Apply the various theories of bioethics with respect to the use of plants.

Write a comprehensive, persuasive essay
Questions to be answered:

What are conventional breeding methods of plant transformation?
“Plant breeding can be broadly defined as alterations caused in plants as a
result of their use by humans...” (Breseghello & Siqueira, 2013). Conventional
methods of breeding plants include crossing together plants with supposed
desired characteristics and then selecting offspring that has inherited
combinations of these characteristics.

Why do we need to breed plants selectively?
In today’s world, the aim of plant breeding is to produce improved plants that
possess desirable characteristics. However, the gene/combination of genes
that code(s) for a desired characteristic may not exist within a species. These
genes could be sourced from different species or even other kingdoms.

Limitations posed by conventional crossbreeding techniques:
While conventional breeding methods have been used extensively to produce
plants with improved traits, these methods are not without limitations.
Conventional breeding methods can be time consuming and often take
several years or even decades to create a new cultivar (Ahmar, et al., 2020).
If the desired trait does not exist within the available genetic pool, genetic
diversity becomes a limiting factor for the potential to improve the plant and
this gives rise to genetic constraints. Conventional methods can also have
unpredictable outcomes (both desired and undesired outcomes) because
genetic interactions can lead to numerous unexpected combinations of traits.
Because of this, it becomes increasingly difficult to achieve the desired
phenotypic outcome. Certain traits in plants can be complex to achieve. Often
involving the alteration of multiple genes, conventional methods of breeding
may not address the processes required to achieve such traits. Conventional
methods of breeding can also be labour and resource intensive with skilled
labour requirements alongside the need for large land. Lastly, conventional
methods of breeding may not be agile enough to become feasible solutions to
rapidly emerging challenges.

What is biotechnology?
According to (Vedantu, 2016), biotechnology is best defined as the use of
scientific techniques to improve and alter plants, animals and microorganisms’
value based on DNA and its concepts. It involves the exploitation of biological
processes especially the manipulation of organisms’ genetic material.

Advantages of using biotechnology?
Techniques from biotechnology have not only increased the efficiency of, but
also quickened the process of selective breeding.
The use of biotechnology tools has facilitated the transfer of genes between
species, and this has led to significant advancements in plants’ resistance to
pests and diseases as well as improving crop yield and quality. Biotechnology
has led to the discovery and development of traits such as herbicide
tolerance, disease resistance and enhanced nutritional content. This poses
several economic benefits for farmers and has greatly reduced our
environmental impact. Through various biotechnological methods such as
tissue culture and cryopreservation, endangered plant species can be
conserved, preserving genetic diversity.

Why is there a need for biotechnology?
Climatic extremes such as global warming and high population growth cause
a wide range of negative effects on plants, their production, quality, and
quantity. These effects significantly increase the world’s demand for food. Left
to deal with the problem of providing more food for a larger population on less
land, biotechnology is tasked with a vital role. It aims at “fulfilling the goal of
attaining food security for the present and future generations” (Munaweera, et
al., 2022). The development of biotechnological techniques makes room for
more precise and faster genetic modifications of plants. Biotechnology also
supports sustainable agricultural productivity to meet food demands as an
adaptation to climate change. “Arguably, the use of biotechnology in
agriculture is deemed to be more effective than that of agrochemicals”
(Vedantu, 2016). The use of biotechnological techniques equips farmers with
tools to manage the costs of productions, making the production of crops
cheaper. Biotechnology can be used to address “situations that combine
multiple needs” (Ahmar, et al., 2020). For example, in golden rice, a single
crop was required to provide both sustainable food and added nutritional
benefits. We can say the golden rice was ‘transformed’, but what is plant
transformation?

What is plant transformation?
For many years, we have used traditional methods of modifying crops to suit
our needs. These methods include crossbreeding, selective breeding, and
mutation breeding. However, according to the U.S (FDA, 2023), the
emergence and development of biotechnology has allowed us to use genetic
engineering to transfer foreign genetic material into plants for desired
outcomes such as higher crop yields, longer storage life, better appearance
and nutrition, less crop loss and even combinations of these traits. Plant
transformation makes use of techniques that directly manipulate the plant
genome. Plant transgenesis is the direct transfer of foreign genes to a plant to
confer specific traits or characteristics, creating a transgenic plant in the
process. As mentioned before, these genes could come from a different
species or even an entirely different kingdom such as bacterium. Plant
transformation has the potential to achieve results that are nearly impossible
with conventional methods of breeding. Some methods used in plant
transgenesis include agrobacterium-mediated transformation, biolistic (gene
gun) transformation, electroporation, microinjection, protoplast transformation
and virus-mediated transformation to transfer desired genes into plants.
Another method used to control the expression of the desired trait is antisense
technology. Antisense technology is an approach that allows the manipulation
of gene expression. Antisense technology has several applications and
benefits including gene silencing and trait modification.

Discuss and explain the ethical concerns of using genetically modified plants?
While biotechnology can be the solution addressing much of the world’s
agricultural challenges, the release of genetically modified plants into the
natural environment warrants careful consideration.
Genetically modified plants have raised a range of health, societal and
environmental concerns. The release of genetically modified plants has raised
health concerns such as allergenicity and toxicity in which the introduction of
foreign genes in crops might lead to the unintended production of toxic
compounds that pose a risk to human health. According to (Raman, 2023),
genetically modified plants could potentially transfer genetically modified
genes to wild, non-target crops. This raises concerns regarding the
preservation of the integrity of our native ecosystems and species. While
enhanced fitness and competitive traits are a desired outcome, they could
lead to invasiveness in genetically modified plants which can eventually
outcompete native species affecting the natural ecological balance (William,
et al., 2014). This potential harm to non-GM crops, biodiversity and
ecosystems raises ecological considerations. Over time, pests and weeds
can grow resistance to the modified traits in plants and this could lead to
increased chemical usage, damaging the environment.
A serious ethical concern arises when patents on genes restrict access to
plant genetic resources. According to (Gaharwar, et al., 2021)This poses an
ethical risk imposed on farmers in developing countries regarding their
exploitation. A lot of ethical concerns exist around the potential health effects
of genetically modified plants as their long-term effects on human health are
debated. It is argued that some important decisions regarding the
implementation of genetically modified crops are not regulated ethically. This
raises ethical concerns about public engagement and transparency as some
regulatory decisions are motivated by corporate and political interests.
To critically analyse the ethical concerns related to biotechnology and the
emergence of genetically modified plants, the Hastings ethical framework,
based on four ethical principles, can be used. One principle outlined in the
framework is autonomy. According to the Merriam Webster dictionary,
autonomy is “the quality or state of being self-governing.” Consumers
autonomy is violated when they unknowingly consume genetically modified
crops due to a lack on informed consent. A second principle outlined in the
Hastings ethical framework is beneficence. This basically describes a state of
doing and/or producing good. Beneficence highlights the environmental
benefits of releasing genetically modified plants versus the potential risks they
may impose on non-target species and ecosystems. The Hastings ethical
framework also describes non-maleficence as an ethical principle associated
with genetically modified plants. Under this principle which requires physicians
not to cause harm, genetically modified plants can have potential unintended
ecological consequences. Lastly, the socio-economic disparities motivated by
GM plants are outlined by the ethical principle of justice. Justice, in simple
terms refers to individuals getting what they deserve. The development of GM
crops does not ensure equal access to the benefits of their genetic alterations
as, according to some companies can patent their discoveries.

What does the future of plant-based biotechnology products look like?
Map plan:
1.
2.
3.
4.
Discuss conventional methods of breeding plants (in a more negative light).
Introduce Biotechnology and present the opportunities it offers.
Contrast plant transformation to conventional methods of breeding plants
Discuss ethical concerns relating to the genetic modification of plants
Bibliography
Ahmar, S. et al., 2020. PubMed Central. [Online]
Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177917/
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Minnesota Libraries Publishing.
Breseghello, F. & Siqueira, G. C., 2013. Traditional and Modern Plant Breeding Methods with
Examples in Rice (Oryza sativa L.). Journal of Agricultural and food chemistry.
FDA, 2023. Agricultural Biotechnology. [Online]
Available at: https://www.fda.gov/food/consumers/agricultural-biotechnology
[Accessed 09 September 2023].
Gaharwar, S. U., Verma, A., Singh, R. & Tulika, P., 2021. Health Risks and Environmental Concerns of
GM Crop Adoption. Policy Issues in Geneticall Modified crops.
Munaweera, T. K., Jayawardana, N. U., Rajarathnam , R. & Dissanayake, N., 2022. Modern plant
biotechnology as a strategy in addressing climate change and attaining food security. Agriculture &
Food security.
Raman, R., 2023. GMOs: Pros and Cons, Backed by Evidence. Healthline.
Vedantu, 2016. Vedantu. [Online]
Available at: https://www.vedantu.com/biology/biotechnology-in-agriculture
William, J., Palladino, A. & Michael, T., 2014. Introduction to Biotechnology. 3 ed. s.l.:Pearson
Education Limited.
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