DR HAFIZ ATIF (FIRST AID MADE EASY PLATFORM) It is temporarily key ,final key will be shared later Q2: What does Amlodipine treat? Key: Supraventricular tachycardia. Q3: What can cause decreased oxygen saturation and cyanosis during anesthesia? Key: Prilocaine. Q4: According to Charles's Law, what is held constant? Key: Pressure. Q5: Which chromosome is associated with Marfan syndrome? Key: 15 chromosome. Q6: What inheritance pattern is seen in Duchenne muscular dystrophy? Key: X-linked recessive. Q7: Which drug can increase INR (International Normalized Ratio)? Key: Clarithromycin. Q8: Which yeast species shows resistance to echinocandins? Key: Candida crusi. Q9: What is the preferred anesthetic for patients with chronic obstructive lung disease? Key: Cisatracurium. Q10: How is vertical nystagmus typically induced? Key: Head tilted sideways. Q11: Which class of antibiotics interferes with neuromuscular transmission? Key: Aminoglycosides. Q12: Which muscle type displays resistance to succinylcholine? Key: M. gravis. Q13: What is the structural basis of steroids like Rocuronium? Key: Rocuronium. Q14: What is recommended for cleaning a face mask? Key: Lukewarm water. Q15: What method is used for sterilizing face masks? Key: Ethylene oxide. Q16: What type of current flow in an ECG generates a wave? Key: Partially depolarization. Q17: What is the main role of the menisci in the knee joint? Key: Weight transmission from thigh to knee. Q18: What type of antigen does MHC-I present? Key: Antigen with CD8. Q19: In the context of blood pressure (BP) readings, if k = 3.2 and the BP is 200/110, what does k represent? Key: Aldosterone. Q20: What aspect of pharmacokinetics is related to the excretion of a drug? Key: Excretion of drug. Q21: Why is epinephrine administered slowly? Key: To increase total peripheral resistance (TPR). Q22: What type of cells are found in damaged brain tissue? Key: Glial cells. Q23: Succinylcholine is classified as a partial agonist of what type of receptor? Key: Nicotinic acetylcholine receptor. Q24: Which anesthetics are associated with malignant hyperthermia? Key: Halothane and nitrous oxide (N2O). Q25: In which conditions is succinylcholine contraindicated? Key: Burns, malignant hyperthermia (use rocuronium instead). Q26: What organism is associated with IUCD use, pelvic pain, and inflammatory cells? Key: Actinomyces. Q27: What is the preferred treatment for ventricular failure and pulmonary edema? Key: Furosemide. Q28: Which drug can decrease the metabolism of theophylline? Key: Cimetidine. Q29: What is the recommended treatment for stable angina after exposure to cold? Key: Nitroglycerin. Q30: During exercise, what does blood flow not change significantly to? Key: The brain. Q31: What do bile acids conjugate with to form bile salts? Key: Glycine and taurine. Q32: Which test is used for diagnosing myasthenia gravis? Key: Edrophonium test. Q33: If sympathetic supply is completely cut at a certain level of section, what happens to all spinal nerves below that level? Key: They are unaffected. Q34: What is the typical composition of spinal nerves? Key: Mixed (both sensory and motor fibers). Q35: What happens to CO2 levels and FEV1/FVC ratio during the last trimester of pregnancy? Key: CO2 levels decrease and FEV1/FVC ratio decreases. Q36: After treating asthma, by what percentage can FEV1/FVC ratio increase? Key: 12%. Q36: What transformation does a platelet undergo to go from flat to spherical? Key: Platelet plug formation. Q37: Which antibiotic is considered safe for use in patients with renal failure? Key: Azithromycin. Q38: Which local anesthetic has the potential to cause cardiotoxicity? Key: Bupivacaine. Q39: What is the recommended treatment for blood loss of 15 to 20%? Key: 3% Normal Saline (NS). Q40: What is the solution for paradoxical aciduria? Key: Normal Saline (NS). Q41: What effect does verapamil have on atrioventricular (AV) conduction? Key: Decreases AV conduction. Q42: What type of personality is associated with Cluster Type A? Key: Physiological stress. Q43: How is the antibiotic dosage adjusted in chronic kidney disease (CKD)? Key: Meropenem > Imipenem. Q44: In a gunshot injury causing contralateral pain loss and intact temperature sensation, which spinal structure is likely affected? Key: Dorsal root of S1. Q45: What property of a volatile anesthetic influences its minimum alveolar concentration (MAC) during inhalation anesthesia? Key: Oil/gas coefficient. Q46: What is the primary effect of diphtheria toxin on protein synthesis? Key: Decreases protein synthesis. Q47: What molecules are associated with cGMP? Key: ANP, BNP, NO (nitric oxide). Q48: What is the main component of the cell wall in Gram-positive and Gram-negative bacteria, respectively? Key: Peptidoglycan; Endotoxin (lipopolysaccharide). Q49: In COPD patients with no metabolic acidosis, what pH level can be expected? Key: pH 7.3. Q50: What neurotransmitters are predominantly found in the raphe nucleus? Key: Serotonin and GABA. Q51: In which brain region are endorphins concentrated? Key: Hypothalamus. Q52: How can hallucinations induced by ketamine be prevented? Key: Combination of ketamine and atropine. Q53: What is the initial physiological response after hemorrhage, and what type of vessel is involved? Key: Vasoconstriction; Arterioles. Q53: Which drug can cause gouty arthritis, tingling in feet, thrombocytopenia, and a decrease in cardiac output? Key: Thiazides (also used to treat calcium stones). Q54: In which type of muscle is insulin predominantly utilized? Key: Resting skeletal muscle. Q55: What is the purpose of fumigation in preventing the spread of infection? Key: Decreases the spread of infection. Q56: Which brain region is responsible for the reticular activating system and the production of norepinephrine? Key: Locus coeruleus. Q57: What is the inflammatory status of apoptosis? Key: Non-inflammatory. Q58: What combination of conditions can cause a pansystolic murmur along with atrial fibrillation? Key: Mitral regurgitation. Q59: What ligament is damaged when the shoulder joint separates from the clavicle and slides over the acromion? Key: Coracoclavicular ligament. Q60: Which muscle separates the submandibular gland into deep and superficial parts? Key: Mylohyoid. Q61: Which structure thickens to form the parotid fascia? Key: Stylomandibular ligament. Q62: What is the cause of hyperacusis in cases of facial nerve palsy? Key: Nerve to stapedius dysfunction. Q63: Which reflex leads to a decrease in muscle tension? Key: Inverse stretch reflex. Q64: In the context of complement fixation, which immunoglobulin is more effective, IgM or IgG? Key: IgM > IgG (3124). Q65: What is the primary effect of neurogenic shock on vasomotor tone and total peripheral resistance (TPR)? Key: Loss of vasomotor tone > Decreased TPR. Q66: Which drug can increase the serum level of another drug? Key: Valproate. Q67: What type of immunity is acquired through the production of antibodies? Key: Acquired immunity. Q68: What term is used to describe immunity acquired by transferring pre-formed antibodies? Key: Passive immunization. Q69: What percentage of plasma is present in the extracellular fluid (ECF)? Key: 30%. Q70: Among anesthetics, which one undergoes extensive metabolism? Key: Halothane. Q71: What is the fixed pO2 split of an oximeter with a low signal-to-noise ratio? Key: 85. Q72: Which nerve is responsible for the loss of taste sensation in the anterior one-third of the tongue? Key: Facial nerve (due to injury to the facial canal). Q73: What is the blood supply of the cricothyroid muscle? Key: External laryngeal nerve (ELN), while all other intrinsic laryngeal muscles are supplied by the recurrent laryngeal nerve (RLN). Q74: What factor is inversely related to laminar flow in fluid dynamics? Key: Viscosity. Q75: What liver condition is characterized by nutmeg appearance and heart failure cells? Key: Chronic passive congestion. Q76: Among pentazocine and phenobarbital, which drug does not respond to naloxone? Key: Pentazocine > Phenobarbital. Q77: What causes diplopia, especially in the setting of a basilar artery lesion? Key: Basilar artery lesion. Q78: What is the dosing schedule for the hepatitis B vaccine? Key: 1 month, 6 months, and 12 months, intramuscularly. Q79: Which artery is responsible for the secondary somesthetic supply? Key: Anterior cerebral artery (ACA). Q80: Which artery supplies the thalamus and subthalamus, and branches from the internal carotid artery? Key: Internal carotid artery. Q81: From which lymph nodes does lymph from the lateral foot drain? Key: Popliteal lymph nodes. Q82: If the unilateral corneal reflex is lost, where is the injury likely located? Key: Superior orbital fissure. Q83: What is the primary cause of vascular resistance increase during surgical stress? Key: Catecholamines. Q84: What is the location of the vomiting center in the brain? Key: Area postrema in the medulla (also called the solitary tract nucleus). Q85: Why is regular checkup necessary after a carotid endarterectomy (CEA)? Key: For follow-up and surveillance. Q86: Which cellular structure contains a large amount of RNA? Key: Nucleolus. Q87: What molecules are involved in opsonization? Key: C3b and the Fc portion of IgG. Q88: What molecules play a role in cell migration or chemotaxis? Key: C5a < LTB4. Q89: In what order do the anaphylatoxins contribute to anaphylaxis? Key: C5a > C3a > C4a. Q90: What is the location of uncontrolled hypertension in cases involving the renal artery? Key: Proximal 2 cm of the renal artery (atherosclerotic lesion). Q91: What is the method used to confirm pregnancy and detect hCG in urine? Key: Enzyme-linked immunosorbent assay (ELISA). Q92: What diagnostic test is typically performed to investigate stillbirth causes? Key: Karyotyping. Q93: Among the carpal bones, which bone is not present in the proximal row? Key: Capitate. Q94: What part of the brain undergoes hydrocephalus after necrosis? Key: Anterior fontanelle. Q95: What artery is located anterior to the third part of the duodenum? Key: Superior mesenteric artery (SMA). Q96: What is the posterior counterpart of the superior mesenteric artery (SMA)? Key: Inferior vena cava (IVC). Q97: Which branch of the dorsalis pedis artery supplies the deep structures of the foot? Key: Deep plantar branch. Q98: In a rotator cuff injury leading to an inability to abduct the arm, which muscle is injured? Key: Supraspinatus muscle. Q99: How does a normal healthy person's blood flow change in response to sympathetic activity? Key: Blood flow increases. Q100: What condition leads to left ventricular hypertrophy due to pressure overload? Key: Left ventricular hypertrophy. Q101: In a case of atrophy and loss of pain and temperature sensation in the lateral leg, what spinal cord structures are affected? Key: Lower motor neuron lesion (LMNL) and anterior horn damage. Q102: What anatomical component surrounds both muscle fascicles and nerve fascicles? Key: Perineurium. Q103: In monozygotic twins, what can differ in terms of pigmentation? Key: Melanocytes. Q104: In spina bifida occulta, what spinal levels are commonly affected when a person can't extend their knee? Key: L3 and L4. Q105: What is the term for a genetic defect that is phenotypically not expressed? Key: Reduced penetrance. Q106: Which chromosome is involved in Prader-Willi syndrome? Key: Chromosome 15. Q107: If the axillary artery is damaged, which branch of it is likely to be affected? Key: Circumflex artery. Q108: What condition is associated with an increase in free bile acids? Key: Hyperlipidemia. Q109: In the act of swallowing, what position are the vocal cords in? Key: Adducted (closed). Q110: What neurotransmitter is prominent in slow wave sleep? Key: Serotonin. Q111: What parameters does a normal distribution curve help determine? Key: Mean and standard deviation. Q112: What is a characteristic feature of an upper motor neuron (UMN) lesion? Key: Exaggerated reflexes. Q113: In the thymus, MHC class I molecules differentiate to form which type of T cell? Key: CD8 T cells. Q114: What structure is found within the inferior orbital fissure? Key: Zygomatic nerve. Q115: What is a characteristic of transitional epithelium in terms of cell shape? Key: Upper cells are dome-shaped. Q116: What inheritance pattern is associated with autosomal dominant conditions? Key: Incomplete penetrance. Q117: What is a condition fatal in pregnancy that involves the liver? Key: Fatty liver disease. Q118: What is the dosing schedule for the hepatitis B vaccine? Key: 1 month, 6 months, and 12 months, intramuscularly. Q119: From which tissue is a sample taken for HLA compatibility testing? Key: Buccal mucosa. Q120: What hormone is secreted by the cortical layer of the oocyte? Key: Estrogen. Q121: What do the receptors in the aortic and carotid bodies detect in response to hemorrhage? Key: Decrease in pO2 (partial pressure of oxygen). Q122: What does the grading of a tumor indicate? Key: Degree of cellular differentiation. Q123: What structure lies anterior to the left suprarenal gland? Key: Lesser sac (omental bursa). Q124: What is a mechanism of tumor metastasis? Key: Down-regulation of E-cadherin. Q125: If ejection fraction increases, what happens to end-diastolic volume (EDV)? Key: Decreases. Q126: At which vertebral body level does the inferior vena cava (IVC) form? Key: L5. Q127: What blood vessel supplies the head of the femur? Key: Retinacular arteries. Q128: What artery provides secondary sensory supply? Key: Anterior cerebral artery (ACA). Q129: Which artery supplies the thalamus and subthalamus and branches from the internal carotid artery? Key: Internal carotid artery. Q130: Where does lymph from the lateral foot drain? Key: Popliteal lymph nodes. Q131: If the unilateral corneal reflex is lost, where is the likely site of injury? Key: Superior orbital fissure. Q132: What is the primary cause of increased vascular resistance during surgical stress? Key: Catecholamines. Q133: What region of the brain houses the vomiting center? Key: Area postrema (located within the solitary tract nucleus). Q134: For what purpose is regular checkup necessary after carotid endarterectomy (CEA)? Key: Follow-up and surveillance. Q135: What cellular structure contains a large amount of RNA? Key: Nucleolus. Q136: What molecules are involved in opsonization? Key: C3b and the Fc portion of IgG. Q137: What molecules are associated with cell migration or chemotaxis? Key: C5a > LTB4. Q138: In what order do the anaphylatoxins contribute to anaphylaxis? Key: C5a > C3a > C4a. Q139: In cases of uncontrolled hypertension, where is the atherosclerotic lesion likely to be in relation to the renal artery? Key: Proximal 2 cm of the renal artery. Q140: How is pregnancy confirmed, and how is hCG detected in urine? Key: Enzyme-linked immunosorbent assay (ELISA). Q140: What is the preferred diagnostic test for investigating stillbirth? Key: Karyotyping. Q141: How is fat digestion primarily accomplished? Key: Emulsification of fats by bile salts. Q142: What type of cells are likely to be prominent in the blood picture of atopic asthma? Key: Eosinophils. Q143: What space is assessed after piercing the interlaminar ligament during a lumbar puncture? Key: Epidural space. Q144: Which protozoan parasite causes malaria and belongs to the Plasmodium genus? Key: Plasmodium falciparum (not an amoeba). Q145: What structural components bound the outlet of the lesser pelvis? Key: Sacrotuberous and sacrospinous ligaments. Q146: Which occupational exposure is closely related to the development of Byssinosis? Key: Cotton (related to cotton dust exposure). Q147: What is the main function of human chorionic gonadotropin (hCG)? Key: Preservation of the corpus luteum. Q148: What is the primary cause of edema in nephrotic syndrome? Key: Hypoalbuminemia. Q149: What is typically seen in the primary focus of tuberculosis (TB)? Key: Calcified pulmonary focus. Q150: Which congenital heart defect is characterized by a "tetralogy" of four specific anatomical features? Key: Tetralogy of Fallot (TOF). Q151: What term is used to describe continuous muscle contraction without relaxation? Key: Complete tetanus. Q152: What bone is not present in the proximal row of carpal bones? Key: Capitate. Q153: What term describes hydrocephalus that occurs after brain necrosis? Key: Anterior fontanelle. Q154: What artery supplies the anterior portion of the third part of the duodenum? Key: Superior mesenteric artery (SMA). Q155: Which major blood vessel is located posterior to the abdominal cavity? Key: Inferior vena cava (IVC). Q156: Which branch of the dorsalis pedis artery supplies the deep structures of the foot? Key: Deep plantar branch. Q157: In cases of rotator cuff injury resulting in an inability to abduct the arm, which muscle is injured? Key: Supraspinatus muscle. Q158: How does the sympathetic nervous system affect blood flow in a normal, healthy person? Key: Increases blood flow (vasodilation) via relaxation of smooth muscle. Q159: What condition leads to an overload of the left ventricle, resulting in hypertrophy? Key: Left ventricular hypertrophy. Q160: What combination of lesions results in atrophy and loss of pain and temperature sensation in the lower leg? Key: Lower motor neuron lesion (LMNL) and anterior horn damage. Q161: What term describes the connective tissue sheath that surrounds muscle fascicles or nerve fascicles? Key: Perineurium. Q162: What characteristic is different between monozygotic twins? Key: Melanocytes (skin pigmentation). Q163: In cases of spina bifida occulta, what spinal levels are typically affected when a person can't extend their knee? Key: L3 and L4. Q164: What term describes a genetic defect that is not phenotypically expressed? Key: Reduced penetrance. Q165: Which genetic condition involves a defect on chromosome 15? Key: Prader-Willi syndrome. Q166: If the axillary artery is damaged, which branch is likely to be affected? Key: Circumflex artery. Q167: What condition is associated with an increased level of free bile acids? Key: Hyperlipidemia. Q168: What is the position of the vocal cords during the process of swallowing? Key: Adducted (closed). Q169: What is the inheritance pattern associated with autosomal dominant conditions? Key: Incomplete penetrance. Q170: What is a condition that is fatal during pregnancy and involves the liver? Key: Fatty liver disease. Q171: What is the primary function of sympathetic beta-1 (B1) receptors? Key: Increase heart rate and contractility. Q172: How is the diagnosis of typhoid typically confirmed? Key: Blood culture or Widal test. Q173: What autoimmune disorder is characterized by dry eyes and dry mouth? Key: Sjögren's syndrome. Q174: What is the primary stimulus for the release of vasopressin? Key: Decreased right atrial pressure. Q175: What molecule helps in the formation of a platelet plug? Key: Thromboxane A2 (TXA-2). Q176: How is cerebrospinal fluid (CSF) absorbed from the subarachnoid space? Key: Arachnoid granulations. Q177: What is the antigen-presenting role of microglial cells in the brain? Key: Antigen-presenting cells (APCs). Q178: What happens to the ciliary muscle during near vision? Key: It contracts. Q179: How does antidiuretic hormone (ADH) affect water permeability in the collecting ducts? Key: Increases water permeability through the collecting ducts (CD). Q180: At what vertebral level does the artery of Adamkiewicz typically arise? Key: Between T9 and L1. Q181: What are some differences between pre-mortem and post-mortem changes in the body? Key: Livor mortis, rigor mortis, and body temperature changes. Q182: What syndrome involves a gastrin-secreting tumor causing peptic ulcers? Key: Zollinger-Ellison syndrome. Q183: What type of metaplasia occurs in the stomach in the setting of adenocarcinoma? Key: Intestinal metaplasia. Q184: What is the approximate ratio of T lymphocytes (T cells) to B lymphocytes (B cells) in the blood? Key: Roughly 2:1 (T:B ratio). Q185: What ligament is responsible for the medial stability of the knee joint? Key: Medial collateral ligament (MCL). Q186: Which artery is the primary blood supply to the gluteal region causing pain? Key: Superior gluteal artery. Q187: In cases of head of the femur dislocation from the acetabulum, which nerve and artery are involved? Key: Sciatic nerve and medial femoral circumflex artery. Q188: What is the location of the facial artery pulse? Key: Anterior to the masseter muscle, along the lower border of the mandible. Q189: At what vertebral levels is the hilum of the kidney located? Key: L1-L2. Q190: At what vertebral levels is pain from the kidney typically felt? Key: L1, L2, L3, and T10. Q191: What side of the diaphragm is inserted into the body? Key: Right side of the diaphragm. Q192: What anatomical structure is found at the left border of the sternum in the 5th intercostal space? Key: Pericardium (heart's sac). Q193: Between what structures does the inferior vena cava (IVC) lie? Key: Between the liver and the diaphragm. Q194: What is the specific type of fracture called that occurs in the distal radius with dorsal displacement? Key: Colles fracture. Q195: Where is the radial artery located in the anatomical snuff box? Key: In the anatomical snuff box, which is located over the scaphoid bone. Q196: What artery supplies the quadrangular space? Key: Posterior circumflex humeral artery. Q197: What term is used to describe veins that accompany arteries? Key: Vena comitans. Q198: What nerve innervates the deltoid muscle and passes through the quadrangular space? Key: Axillary nerve. Q199: What artery supplies the posterior region of the shoulder? Key: Posterior circumflex humeral artery. Q200: Which muscle passes through the Greater Sciatic Foramen? Key: Piriformis. Q201: At what week of pregnancy can Down syndrome be diagnosed using Nuchal Translucency ultrasound? Key: 11th week. Q202: A lady puts her lens in tap water and develops severe retinitis. What is the cause? Key: Acanthamoeba (Naegleria). Q203: How many days does spermatogenesis take? Key: Around 64 days. Q205: What does the Dorsalis Pedis artery supply? Key: Area between the 1st and 2nd metatarsal. Q206: In what configuration is the CMG (cystometrogram) recorded? Key: Indifferent lead placement. Q207: What chromosomal rearrangement is associated with Burkitt translocation? Key: t(8;14) involving c-Myc oncogene. Q208: Which stage of the ECG represents complete ventricular depolarization? Key: QRS complex