Module 14 Pediatric Dosage Calculations Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. Dosage Calculation Based on Weight: Objectives After reviewing this chapter, you should be able to: 1.Convert body weight from pounds to kilograms 2.Convert body weight from kilograms to pounds 3.Calculate dosages based on milligrams per kilogram 4.Determine whether a dosage is safe 5.Determine body surface area (BSA) using the West Nomogram Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 2 Dosage Calculation Based on Weight: Objectives (Cont’d) 6. Calculate BSA using formulas according to units of measure 7. Determine dosages using the BSA 8. Calculate the flow rates for pediatric IV therapy 9. Calculate the safe dosage ranges and determine normal range for medications administered IV in pediatrics Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 3 Background From Cohen, M. (2010): Error rate in children is 3 times higher than in adults Confusion between adult and pediatric formulations Oral liquids available in multiple pediatric strengths Incorrect dilution of medications Look-alike packaging, look-alike names, soundalikes Improper education of parents Calculation errors Errors in measuring devices (household vs. metric) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 4 Background (Cont’d) Make sure dosage is safe. Physiological capabilities are different in infants and children than in adults Two methods to calculate pediatric dosages: Body weight (BW) Body surface area (BSA) based on height and weight Nurse responsible for verifying before giving Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 5 Background (Cont’d): SAFETY ALERT As the nurse administering meds to children, you are legally responsible for recognizing incorrect and unsafe dosages and for alerting the prescriber. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 6 Principles Relating to Basic Pediatric Calculations 1. Use same methods (R&P, DA, Formula) 2. Pediatric doses are smaller (in mcg) 3. IM dosages rarely exceed 1 mL; for small infants, 0.5 mL 4. Subcut dosages are not to exceed 0.5 mL 5. For dosages less than 1 mL, use TB syringe 6. Pediatric doses are rarely rounded to tenths; use TB so hundredths can be given 7. All answers must be labeled 8. Know institution policy on rounding dosages Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 7 Calculation of Pediatric Dosages Based on Body Weight Compare ordered dosage to recommended safe dose range Pounds to kilograms (2.2 lb = 1 kg) To convert pounds to kg, divide pounds by 2.2 To convert kg to pounds, multiply kg by 2.2 • Example 1: Convert child’s BW of 30 lb to kg Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 8 Dimensional Analysis (DA) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 9 Converting Pounds/Ounces to Kg 1. Child weighs 14 lb 6 oz. Convert to kg. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 10 Converting Pounds/Ounces to Kg (Cont.) Mosby items and derived items © 2014, 2010, 2006, 2002, . 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 11 Dimensional Analysis (DA) Convert 14.4 lb to kg SAFETY ALERT Use caution when converting ounces to a fraction of a pound. Remember to add the remaining whole pounds to get the total pounds before converting to kilograms. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 12 Case Study 6 Tara Bates is your 4-year-old patient admitted to the pediatric unit with MRSA infection to the right inner thigh with plans for I and D tomorrow morning. You weigh Tara and find she is 32 lb and 9 oz. You must convert the weight to kg when filling out the surgical checklist. What is Tara’s weight in kg? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 13 Case Study 6 (Cont.) Answer: Tara weighs 14.8 kg. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 14 Converting Grams to Kilograms Neonates are weighed in grams 1,000 g = 1 kg Calculate weight of 3,000 g infant in kg Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 15 Dimensional Analysis (DA) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 16 Review of Concepts Convert the child’s weight in kg—round to 10th Recommended dosage—reputable source Total daily dosage—amount allowed in a 24 hour period Divided doses—amount of drug from total daily dose divided into various increments Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 17 Review of Concepts (Cont.) Safe dose—high and low ranges of recommended versus what is ordered Calculate safe dose by multiplying wt by recommended dose—round to 10th Compare the ordered dose to the recommended dose and determine if the dosage is safe If safe, calculate the amount and administer If unsafe, notify the prescriber Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 18 Review of Concepts (Cont.) SAFETY ALERT Before administering any medication to a child, always ask yourself if the dosage is safe. When in doubt, contact the prescriber before administering. Pediatric medications should always be checked by two nurses. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 19 Single-Dose Medications Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 20 Single-Dose Medications (Cont.) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 21 Single-Dose Range Medications Some medications can indicate a minimum and a maximum range Example 2: Vistaril 15 mg IM q4h prn nausea Child weighs 38 lb. Is the dosage safe? Recommended dose: 0.5 to 1 mg/kg/dose q4h 2.2 lb: 1 kg = 38 lb: x kg X = 17.3 kg Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 22 Single-Dose Range Medications (Cont.) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 23 Single-Dose Range Medications (Cont.) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 24 Case Study 6 (Cont.) You continue with your assessment of Tara and notice that she feels warm to the touch and her cheeks are flushed. An oral temperature reveals a fever of 101.5 ° F. You review the chart and find the following order: Tylenol Elixir (160 mg/5 mL) 150 mg PO q4h prn fever > 99° F The safe dose range reads: 10-15 mg/kg/dose q4-6hr as needed. Is the dose safe? (Tara weighs 14.8 kg) If so, how much will you administer? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 25 Case Study 6 (Cont.) Answer: The dose is safe, administer 4.7 mL AFTER checking calculations and dosage with another nurse. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 26 Pediatric Daily Dosages 1. Calculate total daily dosage 2. Divide daily dosage by number of doses to be administered 3. Use R&P, Formula Method, or DA to calculate number of tabs or caps or mL to administer the dose Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 27 Pediatric Daily Dosages (Cont.) Order: Dilantin 30 mg p.o. q8h. Child weighs 18 kg. Recommended dosage is 5 mg/kg/day in two or three equally-divided doses. Is the dosage safe? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 28 Pediatric Daily Dosages (Cont.) 1. Calculate safe total daily dosage: 5 mg/kg/day x 18 kg = 90 mg per day 2. Determine amount for each dose (3): 30 mg q8h = 30 mg three times daily 30 mg × 3 = 90 mg daily; therefore it is safe Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 29 Calculating BSA for Child Dosing Using Formula A pediatric dosage may be calculated from a recommended adult dosage using a formula The formula uses the average adult dosage, the average adult BSA (1.7 square meters), and the child’s BSA Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 30 Calculating BSA for Child Dosing Using Formula (Cont.) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 31 Case Study 6 (Cont.) Two hours after administering the Tylenol, Tara’s temperature has normalized. The surgical team has been talking to Tara and her mother regarding the procedure. The anesthesiologist asks you to add Tara’s BSA to the chart. You recall her height: 35.5 inches and her weight: 32 lb 9 oz. What is her BSA? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 32 Case Study 6 (Cont.) Answer: Tara’s BSA is 0.61 m². Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 33 IV Therapy and Children Very specific to level of development Use microdrop sets and/or electronic devices Secondary infusions may be delivered as IVPB or in burette (calibrated chamber) Flush tubing (usually with 15 mL or so) after medication delivered, to get all of the medication Check protocol of institution Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 34 Figure 25-2 Volume-controlled device (burette). (From Potter PA, Perry AG, Stockert P, Hall A: Fundamentals of nursing, ed 8, St Louis, 2013, Mosby.) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 35 Calculating IV Medications by Burette Drop factor is 60 gtt/mL Formula: Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 36 Calculating IV Medications by Burette (Cont.) Example: Antibiotic of 100 mg in 2 mL—dilute in 20 mL of D5W to infuse over 30 minutes. A 15 mL flush follows. Administration set is burette. Step 1: Read label to determine volume of medicine available (100 mg:2 mL) Step 2: Allow 18 mL of D5W to run into burette. Add 2 mL containing the medication Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 37 Calculating IV Medications by Burette (Cont.) Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 38 Calculating IV Medications by Burette (Cont.) SAFETY ALERT! IV infusions should be monitored as frequently as every hour. A solution to flush the IV tubing is administered after the medication. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 39 Case Study 6 (Cont.) You are to administer a preop antibiotic to Tara (14.8 kg). The order reads: Vancomycin 148 mg IV over 2 hours q6h The safe dose range is : 40 mg/kg/day in 6-8 divided dosages. Is the dose safe? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 40 Case Study 6 (Cont.) Answer: The dose is within safe range. You have available 500 mg vials that must be reconstituted with 10 mL sterile water for a concentration of 50 mg/mL. This must be further diluted with NS to ≥ 5 mg/mL and administered over at least 60 min. How much of the reconstituted medication will you draw up and how much will you further dilute with? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 41 Case Study 6 (Cont.) Answer: Draw up 3 mL (2.96 rounded) and further dilute with 30 mL NS. You are to administer the medication over 2 hours. Your facility policy requires you to use a Burette with microdrip tubing and a pump. Calculate the rate in gtt/min and mL/hr. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 42 Case Study 6 (Cont.) Answer: Run the infusion at 15 gtt/min and 15 mL/hr. You also remember to flush the tubing at the same rate with an additional 15 mL NS. Tara tolerates the medication well and sleeps through the night without pain or fever. She has been NPO after midnight and she is dressed in a clean gown before she is taken to surgery at 0700. Her mother thanks you for all your help. Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 43 Reminders: Pediatric Oral and Parenteral Medications 1.Dosages for children are smaller than those for adults 2.Most medications for children are liquid 3.Oral route is preferred to parenteral 4.Not more than 1 mL IM for small children and older infants; small infants should receive not more than 0.5 mL IM 5.Parenteral doses are usually given with tuberculin (TB) syringes 6.Calculate dosages to administer using a ratio and proportion, formula, or dimensional analysis Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 44 Practice Problems A child weighing 42 lb 5 oz is prescribed Rocephin 800 mg IV B.I.D. The recommended dosage is 50–75 mg/kg/day 1. Convert the weight to kg. 2. Determine the safe dose range for the child. 3. Is the ordered dose safe? If not, what is your next step? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 45 Practice Problems (Cont.) The prescriber changes the order to Rocephin 500 mg IV over one hour B.I.D. You have on hand Rocephin 2 g per 50 mL. 4. How much will you administer? 5. What will be the rate mL/hr? 6. What is the rate in gtt/min with microdrip tubing? Mosby items and derived items © 2014, 2010, 2006, 2002, 1998, 1994 by Mosby, Inc., an imprint of Elsevier Inc. 46