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olanzapine

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ACTIVE LEARNING TEMPLATE:
Medication
STUDENT NAME______________________________________
olanzapine
MEDICATION___________________________________________________________________________
REVIEW MODULE CHAPTER_25
___________
antipsychotic
CATEGORY CLASS_atypical
______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action
Blocks serotonin, and to a lesser degree,
dopamine receptors. Also block receptors for
norepinephrine, histamine, and acetylcholine.
Therapeutic Use
Relief of psychotic manifestations in bipolar
disorder
Complications
Metabolic sndrome, orthostatic hypotension, anticholinergic
effects, urinary hesitancy or retention, dry mouth. agitation,
dizziness, sedation, sleep disruption, mild EPS (i.e
tremors), elevated prolactin levels, and sexual dysfunction.
Contraindications/Precautions
Should not be used for clients who have dementia. Use
cautiously in clients who have cardiovascular disease,
seizures, or DM. Avoid concurrent use of alcohol.
Interactions
Immunosuppressive medication can further suppress
immune function. Additive CNS depressant effects can
occur with concurrent use of alcohol, opioids,
antihistamines, and other CNS depressants.
Medication Administration
Oral or IM route. Oral
disintegrating tablets, short
acting injectable, and extended
release injection
Nursing Interventions
Obtain baseline fasting BG and
monitor periodically. Monitor
cholesterol, triglycerides, and BG
if weight gain is >14kg. Monitor
BP & HR for orthostatic changes.
Use AIMS test to screen for EPS.
Obtain prolactin levels.
Client Education
Evaluation of Medication Effectiveness
Improvement and prevention of acute psychotic
manifestations, anxiety, and hostility. Improvement in
abilitity to perform ADLS, interact socially, and sleeping and
eating habits.
ACTIVE LEARNING TEMPLATES
Follow a healthy low-cal diet,
engage in regular exercise, and
monitor weight. Observe for
galactorrhea, gynecomastia, &
ameonrrhea, and notify provider.
Avoid alcohol. Observe for
sexual adverse effects.
Therapeutic Procedure
A7
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