TABLE OF SPECIATION 3rd YEAR MBBS PHARMACOLOGY GENERAL PATHOLOGY & MICROBIOLOGY FORENSIC MEDICINE REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 98 PHARMACOLOGY 3RD PROFESSIONAL EXAMAMINATION: THEORY (2023) Theory Marks of theory paper = 120 Time Allowed = 03 hrs Internal Assessment (20%) = 30 Total Marks (MCQs:40%+SEQs:40%+IA:20%) = 150 Pass Marks = 75 Paper-1: (*Marks of MCQ component shall be rationalized to 40% weightage out of 150) 80 x MCQs (1 mark each) (80 Marks) Time =80 min Paper-2: 9x SEQs (7x6 Marks & 2x9 Marks) (60 Marks) Time = 100 min *If a candidate obtains 70 marks is MCQs it will be rationalized as: (70/80*60=52.50) Modules General pharmacology Drugs acting on Autonomic Nervous System (ANS) TOPIC Number of MCQs (80) Recall: 25 Application:55 Branches/division of Pharmacology, Sources & active principles of drugs 1 Routes of administration of drugs 1 Pharmacokinetics 1 Pharmacodynamics 1 Factors modifying actions & doses of drugs Parasympathomimetics Drugs Anti Cholinesterases, Myesthenia gravis Organophosphate poisoning & Oximes 1 1 1 1 Catecholamines 1 1 1 Skeletal Muscle Relaxants 1 Drug treatment of glaucoma 1 Drugs acting on Central Neurotransmission Central Gen Anesthetics 01 (6 marks) 1 Adrenergic Blockers Central Sympathoplegics 01 (6 marks) 1 Cholinergic blockers Non Catecholamines 9 x SEQs (7x6 Marks, 2x9 Marks) 1 1 REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS 01 (9 marks) Page | 99 Nervous System (CNS) Local Anesthetics (LA) Aliphatic Alcohols Sedatives/ Anxiolytics & Hypnotics Anti-epilepsy drugs Antipsychotic drugs Anti-depressants Drugs used in Parkinsonism Drug treatment of Migraine Non Narcotic Analgesics a) Non-steroidal Anti- inflammatory drugs (NSAIDs) b) Drugs used in gout. c) DMARDs/ Biological Agents Opioids Drug Dependence Drugs acting on Cardiotonic drugs Cardiovascular Antihypertensive drugs System (CVS) Drug Treatment of IHD Anti arrhythmic drugs Diuretics Blood Chemotherapy Thiazide Loop/ K sparing Osmotic Carbonic Anhydrase inhibitors Haematinics Anticoagulants Thrombolytic Anti-platelets Anti Hyperlipidemics Introduction & General Principles of Chemotherapy Mechanism of Resistance 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 01 (6 marks) 1 1 1 2 1 1 1 1 1 1 1 01 (6 marks) 1 1 Penicillins 1 Cephalosporin 1 Sulfonamides - 01 (9 marks) 1 Macrolides 1 Tetracyclines 1 REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 100 Chloramphenicol Endocrinology Reproductive System Respiration 1 Aminoglycosides 1 Quinolones 1 Anti- tuberculosis drugs Misc Drugs: Clindamycin, Fusidic acids, vancomycin, Nitrofurantoin, Linezolid Anti fungal drugs 1 1 1 Anti viral drugs 1 Anti Malarial 1 Anti Amoebics 1 Anthelmintics Antidiabetic drugs Thyroid/Anti-thyroid drugs Adrenal Hormones Drug treatment of osteoporosis Sex Hormones Drug used in treatment of Infertility Hormonal contraceptives Oxytocic drugs &Uterine Relaxants Expectorants & Antitussives Drugs used in Bronchial Asthma Antihistamines (H antagonists) Prostaglandins Anti emetics 1 1 1 1 1 1 1 1 1 1 1 1 1 Gastrointestin al System (GIT) Antidiarrhoeals Misc - 01 (6 marks) 1 1 1 Purgatives/laxatives 1 Drugs used in Peptic Ulcer 1 Autacoids 01 (6 marks) 01 (6 marks) 1 Heavy Metal Poisoning & Antidotes 1 Drug – Drug interactions 1 TOTAL 80 (80 Marks) REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS 09 (60 Marks) Page | 101 Pre-Annual/ Annual Professional Exam: Practical (2023) Practical Internal Assessment Total marks Pass Marks Gen Viva Voce = 120 = 30 = 150 = 75 Practical Int Examiner Ext Examiner OSCE/Practic al Notebook 30 30 55 5 Gen Viva + Practical Internal Evaluation 120 30 Total 150 * Lab work: 03 Practical (Observed) (Pharmacodynamics) of 10 marks each = 30 Marks 05 Unobserved stations of 05 marks each = 25 Marks REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 102 GENERAL PATHOLOGY & MICROBIOLOGY 3RD PROFESSIONAL EXAMAMINATION: THEORY (2023) Theory Marks of theory paper = 120 Time Allowed = 03 hrs Internal Assessment (20%) = 30 Total Marks (MCQs:40%+SEQs:40%+IA:20%) = 150 Pass Marks = 75 Paper-1: (*Marks of MCQ component shall be rationalized to 40% weightage out of 150) 80 x MCQs (1 mark each) (80 Marks) Time =80 min Paper-2: 9x SEQs (7x6 Marks & 2x9 Marks) (60 Marks) Time = 100 min *If a candidate obtains 70 marks is MCQs it will be rationalized as: (70/80*60=52.50) TOPICS COURSE Number of MCQs (80) Recall (20) Cell Injury, Cell death & Adaptations Inflammation & repair Disorders of the Immune system General Pathology 2 Cellular adaptations Ischemia & cell injury Necrosis & apoptosis Intracellular accumulations 1 Acute Inflammation Chronic inflammation Wound healing & tissue repair 2 Immune system Hypersensitivity I, II, III & IV, HLA system Tissue transplantation, tolerance & autoimmunity Autoimmune disease Immune deficiency syndrome, AIDS Lab diagnosis of immunological diseases Application(60) Number of SAQs/SEQs (7x6 Marks each 2x9 Marks each) 5 1 5 4 REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS 1 Page | 103 Hemodynamic disorder, Thrombo embolism and shock Genetics & Paediatric disorders Neoplasia Edema, hyperemia & congestion Thrombosis & Embolism Hemorrhage & Shock Infarction Amyloidosis Introduction, Mendelian disorder Multifactorial disorders Cytogenetic disorders Diagnosis of genetic disorders General Microbiology Introduction, biohazards in microbiology lab, infection control measure Bacterial growth and genetics Sterilization and disinfection Bacterial pathogenesis, Normal Flora Gram positive cocci Gram-negative cocci Gram positive rods Gram negative rods Mycobacteria Special Bacteriology 4 1 3 2 Introduction, Carcinogenesis Pathogenesis of tumours Mechanism of spread of malignant tumor Clinical features of tumor & lab diagnosis 1 Environmental diseases Harmful effects of smoking, radiation and alcohol Microbiology Environmental diseases 1 1 5 2 1 - 2 6 1 2 10 2 REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 104 Mycoplasma Spirochetes, Chlamydia, Rickettsia Virology Classification, principles Mycology Parasitology 2 5 1 of viral diagnosis Rabies Hepatitis Viruses Polio virus Herpes viruses HIV/AIDS Measles, mumps and rubella VHF & COVID Rotavirus, norovirus and other important viruses Tumor viruses/Papilloma viruses Superficial Mycosis Deep Mycosis Opportunistic pathogenic fungi Introduction to parasitology, Spread of parasites and its prevention Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis Cryptosporidium parvum Malaria Leishmania, Trypanosomes Cestodes-I & II, Trematodes, Ascaris lumbricoides, Enterobius vermicularis, Ancylostoma and Necator, Trichuris, Trichinella, Strongyloides, Nematodes 1 3 2 5 REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS 1 Page | 105 Infectious diseases/syndro mes Respiratory tract infection Meningitis STDs Urinary tract infections Diarrhea/Dysentery Infections in 1 3 - immunocompromised 80 (80 Marks) TOTAL 09 (60 Marks) Table of specifications for Pre-Annual/Annual Professional Exam: Practical Practical Internal Assessment Total marks Pass Marks Gen Viva Voce Int Examiner Ext Examiner = 120 = 30 =150 = 75 Practical *OSPE Practical Performance Internal Evaluation Total 30 150 Notebook 30 30 36 20 04 *Marks Distribution (OSPE/Practical): Unobserved stations (OSPE): 3 x 12 Stations= 36 marks from list below: REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 106 General Pathology 1. Identify following on slides a. Hyperplasia and Atrophy b. Metaplasia and Hydropic change c. Fatty Change d. Intracellular accumulations (Melanin, Hemosiderin) e. Coagulative necrosis and caseous necrosis f. Acute inflammation g. Chronic inflammation h. Lipoma i. Leiomyoma j. Basal cell carcinoma k. Squamous cell Carcinoma l. Hyperaemia/Congestion m. Coronary thrombus n. Atherosclerosis o. Myocardial Infarction p. Calcification q. Malarial parasites r. LD bodies s. Granuloma t. Lipoma u. Leiomyoma v. Basal cell carcinoma w. Squamous cell Carcinoma 2. Interpret report of lipid profile Microbiology 1. Identify different types of blood culture bottles 2. Demonstrate understanding of blood culture collection technique 3. Identification of different bacteria 4. Interpret Culture and Sensitivity of selected bacteria 5. Identification of fungi and yeast Interpret ELISA report for HIV B & C x. Practical/ Performance: 5 x 4 Practical = 20 marks (Select from the list given below) S. No 1. 2. 3. 4. 5. 6. Practical Topic Gram Stain ZN Stain Catalase Test Coagulase test Oxidase Test S. No 7. 8. 9. 10. 11. Practical Topic Urine R.E Biochemical/ Sugar set Stool R/E/ Ova / Cyst Pregnancy Test Focusing of microscope at low high and oil immersion for identification of tissue Motility Test REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 107 3rd Professional MBBS Examination (2023) FORENSIC MEDICINE Theory Marks of theory paper = 80 Time Allowed = 03 hrs Internal assessment (20%) = 20 Total Marks (MCQs:40%+SEQs:40%+IA:20%)= 100 Pass Marks = 50 Paper-1: 40 x MCQs (1 mark each) (40 Marks) Paper-2: 7x SEQs (5x6 Marks & 2x5 Marks) (40 Marks) Modules Thanatology & Autopsy TOPIC Time =40 min Time = 140 min Number of MCQs (40) Recall:13 Application:27 7 x SEQs (5x6 Marks & 2x5 Marks) Medico-legal aspect of Brain death, Sudden and unexpected deaths Indicators of Death, aspects of, causes, manner, mode and mechanisms of death. Physicochemical changes subsequent to death Death Certification Post-mortem Assessment of Fatal period and post-mortem interval. Post-mortem artefacts 02 03 01 (06 marks) 02 04 01(06 marks) Risks and Hazards of autopsy Autopsy Protocol. Biological and non-Biological materials for laboratory examination Exhumation procedures, its value and limitations Parameters & methods of identification Personal identification & Special techniques and objective Legal aspect of methods of identification Reproduction Methods of determination of age, sex and race with their medico- REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 108 and sexual legal aspects. offences Methods to trace evidence, Locard’s Principle of exchange and its medico-legal significance Sexual Offences and Relevant Sections of Law (Zina and Hudood Ordinance) Infanticide, criminal and nonaccidental violence or abuse to a newborn, infant or child Mechanical injuries Traumatology Asphyxia & Regional Injuries Drugs Special trauma: Transportation injuries, Police torture, and Deaths in Custody. 02 06 02 (05 marks) 03 05 01 (06 marks) Heat, Cold, Electrical injuries Violent death, Mechanical, chemical and environmental asphyxia death and their medicolegal implications Medical Ethics, Powers and jurisdiction of courts consent & negligence, Procedures for inquest, and legal Professionalis Procedures. m, Important Legal terms, Application Professional of relevant Legal sections of the Misconduct, Law in relation penal code to medical Role of a medical doctor in the man, medico-legal system, Medical Forensic Psychiatry & evidence in courts. Legal Procedure of Court attendance Procedure and recording of evidence Law in relation to medical man True and feigned insanity Procedure of restraint of the mentally ill REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 109 Limitations to civil and criminal responsibilities of mentally ill General Toxicology Scope of forensic aspects of toxicology, Common Toxicants in our environments and their abuse Sources of poisons Mechanism of action, Sign and symptoms of poisoning 02 03 01 (06 marks) 02 06 01 (06 marks) 40 (40 Marks) 07 (40 Marks) Management of poisoning Autopsy findings of death due to poisoning Special Toxicology Alcohol Opiates, Opioids and other narcotics Salicylates and paracetamol Hypnotics and Sedatives Stimulants (Cocaine), cannabis Poisonous Plants Venomous insects (Snakes) Inorganic elements, Antimony, Arsenic, lead, Mercury, Phosphorus Volatile Poisons and corrosives Pesticides, Herbicides and Insecticides TOTAL REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 110 Pre-Annual/Annual Professional Exam: Practical Practical Internal Assessment Pass Marks Gen Viva Voce Internal Examiner 20 Ext Examiner 20 = 80 = 20 = 50 Lab Work Practical/OSCE 30 Practical Notebook and Forensic Daybook marks 5+5 Internal Evaluation Total 20 100 REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 111 INTERNAL ASSESSMENT - THEORY INTERNAL ASSESSMENT WEIGHTING: 20% Exams Weightings Attendance in Lectures: 10% >90% = 10 80-89% = 7 75-79% = 5 End of Block/ clinical rotation (theory) Examination 45% Continuous assessment (average score of all tests attempted after every learning session during the academic year) Pre-Annual Exam Total 20% 25% 100% INTERNAL ASSESSMENT STRUCTURE - PRACTICAL INTERNAL ASSESSMENT WEIGHTING: 20% Exams Weightings Attendance in Practicals: 10% >90% = 10 80-89% = 7 75-79% = 5 *End of Block/ clinical rotation (OSCE) Examination 45% *Continuous assessment of practical/ clinical skills and attitude 20% Pre-Annual Exam 25% Total 100% REVISED CURRICULUM (V-II) APPLICABLE FOR MBBS YEAR-III STUDENTS 2023 ONWARDS Page | 112