Draw Mutation
This activity can be modified to draw an illustration and demonstrate what can happen to the phenotype of an organism
when there is a mutation in its DNA.
Materials

Strips of DNA with instructions with and without mutations (see tables)
DNA
without
mutation
TAA
GCG
CCC
TTT
CTA
Instruction
Draw a big circle
Inside the big circle draw two eyes
On each side of the big circle draw 2 semi circles
Below the eyes draw a nose
Draw a lip below the nose
DNA with
mutation
TAA
GCT
TTT
CTA
Instruction
Draw a big circle
Inside the big circle draw uneven eyes
Below the eyes draw a nose
Draw a lip below the nose
Activity Instructions
1.) Each group of students will choose on part of the activity they going to perform.
2. Read the DNA and then follow its instructions.
3.) This chosen group activity will be performed by members through pair and share on a half sheet of paper.
4.) Each student needs to read his or her DNA code and then follow the instructions, passing down the table to take turns
in following each instructions.
Draw Mutation
This activity can be modified to draw an illustration and demonstrate what can happen to the phenotype of an organism
when there is a mutation in its DNA.
Materials

Strips of DNA with instructions with and without mutations (see tables)
DNA
without
mutation
TAA
GCG
CCC
TTT
CTA
Instruction
Draw a big circle
Inside the big circle draw two eyes
On each side of the big circle draw 2 semi circles
Below the eyes draw a nose
Draw a lip below the nose
DNA with
mutation
TAA
GCT
TTT
CTA
Instruction
Draw a big circle
Inside the big circle draw uneven eyes
Below the eyes draw a nose
Draw a lip below the nose
Activity Instructions
1.) Each group of students will choose on part of the activity they going to perform.
2. Read the DNA and then follow its instructions.
3.) This chosen group activity will be performed by members through pair and share on a half sheet of paper.
4.) Each student needs to read his or her DNA code and then follow the instructions, passing down the table to take turns
in following each instructions.
Mutation Sentences
This activity goes into more detail about insertion, deletions, and silent mutations and can be used as a follow-up to the
Drawing Mutation activity (or as a standalone activity).
Codon
Word
Codon
Word
AAA
I
CGG
Have
AAC
Dog
CTC
Big
AAT
Eat
GGG
Day
CAT
Cats
GTT
Long
CCG
A
TAA
Rat
CGC
All
TTA
Hairy
Activity Instruction
1). Students are going to use the key to decode the DNA and see what it produces.
2. Read the DNA and then follow its instructions.
3.) This chosen group activity will be performed by members through pair and share on a half sheet of paper.
4.) Each student needs to read his or her DNA code and then follow the instructions, passing down the table to take turns
in following each instructions.
5). Decode the DNA
1. AAACGGCCGCTCTTAAAC
2. AAACGGCCGCTCTTAAATC
Mutation Sentences
This activity goes into more detail about insertion, deletions, and silent mutations and can be used as a follow-up to the
Drawing Mutation activity (or as a standalone activity).
Codon
Word
Codon
Word
AAA
I
CGG
Have
AAC
Dog
CTC
Big
AAT
Eat
GGG
Day
CAT
Cats
GTT
Long
CCG
A
TAA
Rat
CGC
All
TTA
Hairy
Activity Instructions
1). Students are going to use the key to decode the DNA and see what it produces.
2. Read the DNA and then follow its instructions.
3.) This chosen group activity will be performed by members through pair and share on a half sheet of paper.
4.) Each student needs to read his or her DNA code and then follow the instructions, passing down the table to take turns
in following each instructions.
5). Decode the DNA
1. AAACGGCCGCTCTTAAAC
2. AAACGGCCGCTCTTAAATC