PSICOLOGIA E SAÚDE EM DEBATE ISSN (eletrônico) 2446-922X THEORETICAL STUDY HYPNOSIS: definition, importance, limitations and evidencebased possibilites DOI: 10.22289/2446-922X.V8N2A14 Filipe Luís Souza 1 Camilla Volpato Broering ABSTRACT The primary objective of this review is to analyze the main theoretical perspectives that define hypnosis, the value of considering it as a unique phenomenon, the evidence that sustains that view, and its effect on research. For more than a century in which the subject has been studied, the results are still hampered by a methodological flaw since the beginning of the research, the definition of the phenomenon. This review used the Medline via Pubmed as database for bibliographic search, including a total of 41 studies, where it could be found that 72,7% of the surveyed studies, adopt the approach in which there's an alternate state of consciousness to explain the phenomenon and to guide its interpretations, even though there isn't enough evidence to sustain the existence of an alternate state of consciousness exclusively hypnotic and it's relation to the capability of hypnotic response. In conclusion, it's suggested the performance of more studies that bring a merger between sociocognitive and state of mind perspectives, so that the findings can come to help with the evolution of hypnosis, which already presents strong results when applied in different medical and psychotherapeutic treatments, predominantly in the Cognitive-Behavioral Therapy. Keywords: Hypnosis; Evidence-based Practice; Magnetic Resonance Imaging. HIPNOSE: DEFINIÇÃO, IMPORTÂNCIA, LIMITAÇÕES E POSSIBILIDADES BASEADAS EM EVIDÊNCIAS RESUMO O objetivo primário desta revisão é analisar as principais perspectivas teóricas que definem o que seria a hipnose enquanto fenômeno, analisando também as evidências que as sustentam e suas aplicações em pesquisas, vez que, por não haver um consenso na comunidade científica sobre sua definição, há mais de um século em que o fenômeno é pesquisado, os resultados potenciais dos achados podem estar comprometido por uma falha metodológica na gênese das pesquisas. Esta revisão utilizou a Medline via Pubmed como base de dados para levantamento bibliográfico, incluindo um total de 41 estudos, onde constatou-se que, 72,7% das pesquisas, levantadas, utilizam uma perspectiva de estado alterado de consciência para explicar o fenômeno e guiar a interpretação de seus achados, mesmo que não existam evidências que sustentem a proposição da existência de um estado alterado de consciência exclusivamente hipnótico e sua relação com a capacidade de resposta hipnótica. Por fim, propõe-se a realização de mais estudos que tragam uma integração entre perspectivas sociocognitivas e estatais, menos espaçadas, para que os achados venham auxiliar na evolução da hipnose, que já possui 1 Endereço eletrônico de contato: filipe.souza@clinicasouzaecabral.com Recebido em 12/09/2022. Aprovado pelo conselho editorial para publicação em 07/12/2022. Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. *Page numbers adjusted according to the original in brazilian portuguese. 226 forte corpo de evidências em diferentes quadros de tratamentos médicos e psicoterápicos, sobretudo na Terapia Cognitivo-Comportamental. Palavras-chave: Hipnose; Prática Baseada em Evidências; Imagem de Ressonância Magnética. HIPNOSIS: DEFINICIÓN, importancia, limitaciones y posibilidades basadas en la evidencia RESUMEN El objetivo principal de esta revisión es analizar las principales perspectivas teóricas que definen la hipnosis, el valor de considerarla como un fenómeno único, la evidencia que sustenta esa visión y su efecto en la investigación. Durante más de un siglo en el que se ha estudiado el tema, los resultados todavía se ven obstaculizados por una falla metodológica desde el inicio de la investigación, la definición del fenómeno. Esta revisión utilizó Medline vía Pubmed como base de datos para la búsqueda bibliográfica, incluyendo un total de 41 estudios, donde se pudo encontrar que el 72,7% de los estudios encuestados, adoptan el enfoque en el que hay un estado alternativo de conciencia para explicar el fenómeno y guiar sus interpretaciones, a pesar de que no hay suficiente evidencia para sostener la existencia de un estado alternativo de conciencia exclusivamente hipnótico y su relación con la capacidad de hipnótico. respuesta. En conclusión, se sugiere la realización de más estudios que traigan una fusión entre las perspectivas sociocognitivas y del estado de ánimo, de modo que los hallazgos puedan ayudar con la evolución de la hipnosis, que ya presenta resultados sólidos cuando se aplica en diferentes tratamientos médicos y psicoterapéuticos, predominantemente en la Terapia CognitivoConductual. Palabras clave: Hipnosis; Práctica basada en la evidencia; Resonancia magnética. 1 INTRODUCTION Hypnosis is the oldest form of Western psychotherapy (DeSouza et al., 2020). Currently, approaches such as the Cognitive-Behavioral Therapy (CBT), are already well supported regarding its functioning and resolution of mental disorders. From the concepts of Radical Behaviorism added to the understanding of cognitive theories, the CBT was created and, with a robust framework of evidence showing its effectiveness in the treatment of the main mental disorders. CBT is highly effective in the treatment of anxiety disorders such as ObsessiveCompulsive Disorder (OCD), Post Traumatic Stress Disorder (PTSD), Panic Disorder (PD), Generalized Anxiety Disorder (GAD), Social Anxiety (SAD), Specific Phobias and Agoraphobia (Carpenter et al., 2018; van Dis et al., 2020; McGuire et al., 2015). Based on what common sense expects from the results of a psychotherapeutic intervention, the evolution of Evidence-Based Psychology has shown through multidisciplinary studies how psychotherapy is actually a biological treatment. Thanks to recent discoveries, it’s stated that more than 50% of deaths worldwide are attributable to diseases related to the inflammation of a person’s body, and the state of chronic inflammation can be associated with heart problems, diabetes, cancer, arthritis Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 227 and bowel diseases (Harvard Health Publishing, 2020). In addition to that, it’s also known, with support from 56 clinical trials and a total of 4060 participants, that CBT demonstrates improvements to our immune function (Shields, Spahr & Slavich, 2020). Additionally and as a means of diversifying the sample base of this manuscript, the third wave of cognitive therapies brings approaches such as Dialectical Behavior Therapy (DBT), indicated for the treatment of other clinical conditions, such as the treatment of Major Depressive Disorder (MDD), substance abuse and Post Traumatic Stress Disorder (PTSD). DBT is highly effective in decreasing the incidence of self-harm as well as suicide attempts (McCauley E. et al., 2018). Along with the evidence of psychological treatment methods developed in the West, another great advance that benefits those affected by mental disorders, is pharmacotherapy. So far, it is known that major depressive disorder is one of the most common and burdensome mental disorders for adults worldwide, and even though there are non-drug interventions for it, antidepressant medications are still used more frequently. One of the reasons this happens, mentioned by Cipriani et al. (2018), is the inadequate amount of resources for other means of treatment, which reinforces the need for new and better-based tools in psychological interventions. With 522 studies involving 116,477 participants, 21 tests of psychiatric drugs were applied and systematically compared to the treatment of major depressive disorder in adults and, in terms of efficiency, all antidepressants were more effective than placebo (Cipriani et al, 2018). Taking into account the theme of this study and the concern in evaluating an accelerator of clinical results, one should look further into the drugs and their correct usage. As an example of the theme, it’s possible to observe an audience that suffers a lot from depressive disorders, adolescents and children, and after reviewing 71 trials involving 9,510 participants, it was found that no pharmacotherapy alone was more effective than psychotherapy alone, and despite the low amount of evidence of relevant quality, fluoxetine (by itself or in associated with CBT) proved to be the best choice for the acute treatment of moderate to severe depressive disorder in children and adolescents (Zhou et al, 2020). Even with psychological and pharmacological interventions, from 76% to 85% of the population in low- to middle-income countries do not receive any treatment for their disorder (James et al, 2018). When dealing with the relationship between psychological approaches and effectiveness, one should focus on optimization flow, I.e. , making the experience of realizing a bad state of mind to seeking and finding help as fast as possible. Thus, starting the treatment faster and so, having your recovery also in a faster way, as shown by comparative research between the effectiveness of psychoanalytic approaches in psychotherapy or not, compared to antidepressants (Eysenck, 1952), therefore, here is presented a possibility of optimizing and accelerating the psychotherapeutic process, using hypnosis in psychological interventions (such as CBT, DBT and others). In the clinical context, researcher Irving Kirsch, reports that hypnosis is a therapeutic tool that can be used along with any therapy Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 228 in which the professional applying it is competent (Carvalho, 2010) and when talking about hypnotherapy, it’s important to remember that it has no theory of personality of its own, or a specific perspective of the world and of people,as well as no exclusive technique to the hypnotic methods. This brings light to the conclusion that hypnotherapy by itself does not exist, it boils down to its “trade name”, when in reality it’s the use of hypnosis as a booster for results associated with the tools of some other therapeutic approach. In patients with clinical depression in a state of palliative care, cognitive hypnotherapy (CH - hypnosis associated with CBT) has been shown to be able to develop antidepressant neural circuits, effective in the treatment of depression, thus being a catalyst for approaches based on mindfulness (Alladin & Alibhai, 2007). ; Lynn et al, 2010) and so being able to provide a multitude of tools for the psychological management of depression (Alladin, 2018). Meta-analytic evidence suggests that hypnosis may be more effective than mindfulness in relieving anxiety, and in interventions where hypnosis was associated with CBT (HC), it was produced a large effect of 1.25, in comparison to when used as a single treatment, which produced an average effect of 0.70 (Valentine et al., 2019). Other meta-analytic evidence suggests that hypnosis has an immediate effect on anxiety in cancer patients (Chen et al., 2017). Another positive aspect for the use of hypnosis is its benefits in the treatment of chronic pain (Machado, Silva & Silva, 2021), stimulating neural plasticity, increasing patient motivation and increasing the tools for pain management, including in diseases like multiple sclerosis. The idea of adding clinically based hypnosis is not new, in 1995 it was demonstrated through a meta-analysis of 18 studies in which CBT was compared with CBT itself but with the addition of hypnosis. The findings were that with HC, patients showed greater improvement than at least 70% of clients who received non-hypnotic treatment. However, it was even more impressive with the results of obesity treatment patients who continued to lose weight even after the treatment ended (Kirsh et al, 1995). Hypnosis is a tool that needs better evidence about its clinical effectiveness, especially in the description and definition of the phenomenon, although there are already other cientifical pieces making a conceptual redefinition and integrating neurobiology with sociocognitive theories (Gruzelier, 2000), the use and dissemination of the information that hypnosis would be an “altered state of consciousness” not only keeps society away from the possible benefits obtained through the hypnotic process, but also keeps hypnosis away from the respectful gaze of health professionals. The present study analyzed which theoretical perspectives have clinical applicability, added to an evidence-based theoretical perspective and its possibilities, since the current scenario in the field of hypnotism is divided, mostly, between hypotheses of altered state of consciousness and sociocognitive hypotheses, both , derived from the five best-articulated views of hypnosis in the scientific community today (Kirsch, 2011), namely: qualitative state hypothesis, quantitative state hypothesis, no-state hypothesis, weak state view and epiphenomenal hypothesis. The data remains inconclusive and inconsistent as to the existence of an altered hypnotic state of Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 229 consciousness and its causal relationship with the human ability to respond to suggestions, as numerous neuroimaging studies show the association of hypnosis with changes in neural activation patterns but, these can also be simply associated with the normal variation of brain activity (Tuominem et al., 2021), however, the lack of confirmation of an altered state of consciousness, at any time, seems to change the mass application of state theories in the academic environment and in the clinical practice. 2 DEVELOPMENT Method The present study is an integrative review, based on the survey of literature data, published from Jan/2017 to 21/Jan/2022. The literature reviewed came from a single scientific database, Medline via Pubmed. Integrative reviews bring relevant contributions to an evidencebased practice in the field of health, since, considering its systematization, the production of the synthesis of knowledge taken by different studies on a phenomenon in common, expands the frontier of human knowledge and has repercussions on health care practice. In the research, it was considered the following English descriptions : “hypnosis definition”, “hypnosis AND sociocognitive” and “hypnosis AND fmri”. Since this is an integrative literature review based on operational steps, as a first step the guiding question is drafted: Which theoretical perspective best comes close to defining hypnosis? In the second stage, the criteria for inclusion and exclusion of studies is established only to add studies that contribute to the discussion of the guiding question, providing support for different theoretical perspectives of the definition of hypnosis. Through this search method, 65 publications potentially eligible to be included in this review were initially identified. Then, without evaluating only by titles, a full reading of the publications was carried out in order to identify if at a certain point of the studies, a theoretical perspective of hypnosis would be presented. The articles included in the analysis performed in this research were selected only those that followed the following criteria: (a) chronology dated from 2017 on; and (b) articles that contribute to the line of thought provided by the guiding question. After reviewing the pieces, 41 articles that followed the criteria described above, were selected and included. Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 230 231 Figure 1 - Identification and selection of publications surveyed using the keywords “hypnosis definition”, “hypnosis AND sociocognitive” and “hypnosis AND fmri”, according to the chronology Jan/2017 to Jan /21/2022. Discussion Since the birth of a concept, the debate and research about it begins, therefore, hypnosis would not be an exception to this rule. Research on hypnosis and its possibilities start from the definition of what hypnosis would be when considered a phenomenon, being then directed to research funds, conducting experiments, collecting and interpreting data and all of this meaning: everything depends on the creation of the concept we’re studying. There is a growing concern with the old problem about the existence or non-existence of a hypnotic state (Bartolucci and Lombardo, 2017). In the bibliographic survey carried out, there was a greater application of the concept that hypnosis is an altered state of consciousness, in which, from a reduced peripheral state of consciousness and focused attention and thoughts abandonment, we can see an improvement in response to suggestions (Otte et al., 2020; Taylor and Genkov, 2019; Krouwel, Jolly and Greenfield, 2019; Keefer et al., 2022; Jiang et al., 2017; Liu et al., 2020; Halsband and Wolf, 2019; Li et al., 2020; Liu et al., 2018; Chadderdon et al., 2020; Casiglia et al., 2020; Koban Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. et al., 2017; Napp et al., 2021; Walsh et al., 2017; Wolf et al. al., 2022; Li et al., 2019; Sanyal et al., 2022; Frati et al., 2019 and Komesu et al., 2017). By saying that the vision of an altered state of consciousness has a greater current applicability, the present article does not do it with the intention of verifying the quality or validity of its application, only reporting the findings in quantitative terms. In the bibliographic survey, it was also possible to notice the application, in a smaller number, of neo dissociative views of hypnosis, which has the principle that hypnosis would occur as a dissociative self state and where it would be the generating fact of a temporary separation between the connectivity of self-monitoring and the brain’s executive processes, which would thus influence the human behavior (Wawrziczny, Buquê and Picard, 2021; Wahbeh and Radin, 2017; Pancheri et al., 2017; Facco et al, 2019 and Bastos Jr. et al. ., 2021). As in the altered state of consciousness view, in dissociative theories, attention and concentration would also be less sensitive to irrelevant stimuli (Facco et al., 2019). Table 1 - Survey of theoretical perspectives of hypnosis applied in research with functional magnetic resonance (fmri) Theoretical perspective Authorship Research object Jiang et al., 2017 State (Standard) Functional alterations of the DMN, ECN and SN and their association with hypnosis and hypnotizability Komesu et al., 2017 Methodology for a trial of brainState (Standard) centered versus anticholinergic therapy in women with urgency urinary incontinence Koban et al., 2017 Mechanisms involved in the influence and changes in the perception of pain and emotion through speech, instructions, placebo and hypnosis Walsh et al., 2017 State (Standard) Brain mechanisms in the loss or reduction of consciousness and movement in neuropsychiatric disorders and dissociative phenomena Derbyshire et al., 2017 Suggestions to Reduce Clinical Sociocognitive Fibromyalgia Pain and Experimentally Induced Pain Produce Parallel Effects on Perceived Pain but Divergent Functional MRI–Based Brain Activity Liu et al., 2018 Investigation on the Neural Mechanism State (Standard) of Hypnosis-Based Respiratory Control Using Functional MRI Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. State (Adjustments) 232 Solitário et al., 2018 Review of neuroimaging studies related to pain modulation in subjects with high and low levels of hypnotic susceptibility Trujillo-Rodriguez et al., 2019 Mechanisms underlying the modulation State (Standard) of pain perception under hypnotic conditions mediated by the anterior and prefrontal cingulate Halsband & Wolf, 2019 Functional Changes in Brain Activity State After Hypnosis: Neurobiological (Adjustments) Mechanisms and Application to Patients with a Specific Phobia— Limitations and Future Directions Facco et al., 2019 Dissociative identity as a continuum from healthy mind to psychiatric disorders: Epistemological and neurophenomenological implications approached through hypnosis. Dissociative Picerni et al., 2019 Cerebellar Structural Variations in Subjects with Different Hypnotizability Sociocognitive Rainville et al., 2019 Hypnotic automaticity in the resting brain Sociocognitive Li et al., 2019 Neural mechanisms of hypnosis-based State (Adjustments) treatment in smoking, specifically, when hypnosis involves a top-down or bottom-up regulatory mechanism Frati et al., 2019 Description of the results of a preliminary experience of a cohort of patients operated on with an original protocol of hypnosis-assisted awake surgery Liu et al, 2020 Physiological performance altered in State hypnosis through temporal fluctuation, (Adjustments) control of respiratory movement and synchronization of the signal of brain activity Li et al ., 2020 The neural mechanisms of immediate State (Standard) and follow-up of the treatment effect of hypnosis on smoking craving Chadderdon et al., 2020 State (Standard) Mechanisms of psychological interventions for their application in patients who need to undergo MRI and Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. State (Standard) Dissociative 233 interventional radiology Casiglia et al., 2020 State (Standard) Brain mechanisms involved in analgesia with hypnotic focus from functional magnetic resonance imaging in 20 highly hypnotizable subjects Napp et al., 2021 Audio self-hypnosis as a way to reduce State claustrophobia during MRI (Adjustments) Bastos Jr et al., 2021 Corpus callosum size, hypnotic susceptibility and empathy in women with alleged mediumship: a controlled study. Sociocognitive Wolf et al., 2022 Systematic review of functional changes in brain activity during hypnosis State (Standard) Sanyal et al., 2022 Introduction of hypnotherapy as a State therapeutic option for stroke treatment (Adjustments) Note - In the making of this dataset, the articles that used the same state perspective, I.e., that hypnosis is a state of consciousness that involves focused attention and reduced peripheral awareness characterized by a greater ability to respond to suggestion, were classified as “State (Standard)”. Articles that presented a theoretical state perspective but with the presentation of small changes in their definitions, flowing between hypotheses of qualitative, quantitative and weak state, were grouped as “State (Adjustments)”. Articles that present hypnosis as a dissociative phenomenon were indexed as “Dissociative” and articles that presented hypnosis as a phenomenon dependent on social, cognitive and expectation variables were indexed as a “Sociocognitive” perspective. Figure 2 - Generalization and opening of the theoretical-state spectrum. Note - The supremacy of the applications of state perspective theories (Graph A) on hypnosis in the field of neuroscientific research is verified. However, when increasing interest in it, a spectrum of hypnosis definitions is observed (Graph B) within a spectrum that precedes them. Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 234 In theorizing the phenomenon of “hypnosis”, sociocognitive perspectives (non-state view and epiphenomenal hypothesis), on the other hand, reject the views of hypersuggestibility generated by the altered state of consciousness (hypnotic trance) as responsible for our ability to respond to hypnotic suggestions and begin to theorize the hypnotic response as the product of a variety of attitudes, beliefs, imaginative abilities, dream capacities and above all, a person’s expectations, which is potentially changable (Short, 2018). Not even within theories of state, hypersuggestibility finds refuge, according to Janet (1925, p. 282, apud Short, 2018): “It is very doubtful that hypnosis can be considered an increased suggestibility. Certain subjects are more suggestible in the waking state than during hypnotic sleep.” There is no consensus on the definition, natural or theoretical perspective. It is known that in general when a phenomenon involves induction, relaxation and suggestions (directly or indirectly), it will usually be called hypnosis (Lam et al., 2018). Research on hypnosis in addition to being carried out, almost entirely, with healthy subjects with high hypnotizability scores (Solitário et al., 2018), ignore other data that would be relevant, such as the morphological variations found in the cerebellar structure that extends and takes away the corticocentric view of hypnotizability (Picerni et al., 2019), a restrictive view of hypnosis as a state of decreased consciousness and peripheral perception as a result of the altered activity of regions, specifically, of the cortical regions. The sociocognitive proposal brings to light the possibility of understanding hypnosis as a behavior involving the motivation of the subject, who is submitted to social and psychological influences like any other person. The subject’s expectations, including their expectations about the word “hypnosis”, must be taken into account, since it makes hypnotic experiences to be seen as a continuum of social influence on human behavior and cognition (Jiang et al., 2017). There are many problems that are born from the idea of the existence of a hypnotic trance, in addition to the fact that this research has been carried out for more than a century to solve this debate and the evidence being ambiguous regarding the alterations in neural functioning that would support the state view, Its existence is even contradictory based on the functional changes found to date since, based on them, hypnosis, meditation and near-death experiences could be the same thing (Facco et al., 2017). Besides, it is known that task motivation instructions can reproduce the same effects of hypnotic induction, creating a similar response to that of the hypnotic suggestion (Bartolucci and Lombardo, 2017), added to these data and moving towards a more neurophysiological view, the OXTR gene polymorphism is associated with a tendency and ability to focus more on internal experiences, which would increase hypnotizability (Bryant et al., 2014 apud Santarcangelo and Scattina, 2019), following a state view, however, the release of oxytocin after induction is higher in subjects identified with low and medium hypnotizability (Varga & Kekecs, 2014 apud Santarcangelo and Scattina, 2019). The data provided reinforces the Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 235 hypothesis that although there is a need to quantify the observed phenomena, everyone can respond to hypnosis to a certain level but, every scale is always intimately linked to the definition of the observed and described in the study, therefore the accuracy and reliability of the hypnotizability scales are found to be lower than desired (Facco et al., 2017). Nothing that hypnosis does, cannot be replicated without it (Derbyshire et al., 2017) even if to a lesser extent, evidence points to how everyone can respond to hypnosis, even if by different neurophysiological mechanisms (Santarcangelo and Scattina, 2019). In the bibliographic survey, it was possible to find a single article on the use of hypnosis as analgesia measured by the cingulate, which when delimiting what was treated by hypnosis, specified that it does not have, until this day, specific neural correlates and that hypnosis itself , produces changes in the perceptual experience through suggestions and responses (Trujillo-Rodriguez et al., 2019), so it’s clear that the community is aware of the structural flaw of state theories, just not replicating true delimitations when describing it. The perpetuation of theories that stipulate hypnosis as an altered state of consciousness, purely and simply, generate a distance from its initial purpose and as society appropriates institutional knowledge, it interprets it freely, transforming different experiences and phenomena into “hypnosis”. ”, then applying the term to describe exorcisms, laying on of hands and other rites, doing not only a cultural injustice (Wickramasekera 2º, 2020) but also generating a social “conditioning” that hypnosis exerts different possibilities on the human “mind”. In the academic scenario this can be ignored, in everyday situations, the possibility of the existence of an altered state of consciousness that has the ability to change perceptions through simple suggestions, based on mentalistic theories or not, makes it possible for hypnosis to be used as a possible treatment for reversing sexual orientation and/or gender identity (Alempijevic et al., 2020), all around the world and under state’s endorsement. 3 CONCLUSION The premise of the theoretical state perspective is as necessary for hypnosis as Descartes' radical localizationist school was for the neurosciences. Its pedagogical use is easily seen, since it undergoes so many changes when explained, a phenomenon that is perceived when observing state hypotheses not as a block but as a spectrum (Figure 2). Hypnosis generates changes in brain functioning, this is a sustained statement. What is concluded is the need not to abandon a theoretical perspective for the empowerment of another, it is necessary to adopt a multi-theoretical model (Bartolucci and Lombardo, 2017), adding the understanding of hypnosis as a behavior and the influence of expectations, as well as its neural correlations, looking for its neuronal markers. The results obtained on hypnosis, to date, already allow us to reconcile the sociocognitive perspective with theories of state (Rainville et al., 2019), since understanding Rev. Psicol Saúde e Debate. Dez., 2022:8(2): 226-245. 236 hypnosis as a process linked to human communication and in turn, linked to the behavior of being motivated to collaborate with a certain suggestion (sociocognitive hypothesis), is a possibility. From this, one can understand their neural correlates using the literature on the effects induced by expectation that affect aspects of self-representation that in turn, produce an alteration in the subject's subjective perception. If an experiment seeks to understand the applicability of hypnosis and its range of possibilities based on evidence to favor individual and/or collective human health in the most diverse clinical and neuropsychiatric conditions, doing it with a methodological error in its genesis, logically, will guide its result, inevitably, to the minimum contemplation of the full potential of hypnosis. Used as treatment for stroke (Sanyal et al., 2022), form of therapy for urinary incontinence (Komesu et al., 2017), alternative control of chronic pain and acute pain during invasive surgery (Derbyshire et al., 2017), hypnosis is used as a tool in so many other activities in different areas of human health, which are not part of the body of discussion of this article, therefore, regardless of the theoretical perspective, its application is beneficial and known to people, the establishment and reverberation of a socio-cognitive perspective with the neuroimaging research apparatus and other technologies used in experimental state vision research, would point to a healthier public reception with still springing possibilities. 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