Diploma In Nursing First Year IPC Microbiology Assignment Kaitlyn Edwin Student Number – 0002221808 Lecturer – Marna Rautenbach DNIPC1B 11/15/2022 Contents Introduction ............................................................................................................................................ 2 Topic 1: Health care associated infections ............................................................................................. 3 A. Intravenous lines ............................................................................................................................ 3 B. Nebulizer masks .............................................................................................................................. 4 Topic 4: Notifiable Diseases .................................................................................................................... 5 Conclusion ............................................................................................................................................... 8 Bibliography ............................................................................................................................................ 9 Appendices............................................................................................................................................ 11 1 Introduction Microbiology, commonly known as the study of microorganisms or microbes, is the study of a wide range of typically small, basic life forms, such as bacteria, viruses, and archaea. The structure, categorization, and use of such organisms as well as methods for directing and manipulating their behaviour are all topics covered in this study. Medical microbiology consists of identifying bacteria for the diagnosis of communicable disorders and determining the likelihood that they will respond to therapeutic measures. In this assignment it will be more revealed on how these agents of microbiology contribute to healthcare associated infections (which is narrowed down to the nursing practice of intravenous lines and nebulizers) and notifiable diseases such as Hepatitis B, Tuberculosis, and COVID-19. With a greater understanding of these bacteria because of microbiology, a healthcare worker can ensure the safety and well-being of a patient whose immune response has weakened and who is constantly at risk of contracting any microorganism while under the care of a nurse 2 Topic 1: Health care associated infections A. Intravenous lines The patient's body can get certain substances through intravenous lines. Through an IV, the body receives fluids such as blood, medicine, or other fluids. The most frequent location for IV insertion is an arm vein, however other locations may also be used, dependent on the clinical condition of a patient. The three types of intravenous lines are peripheral IV’s, midline catheters and central lines. A medical ward inspection revealed that nurses keep inconsistent documents, particularly those pertaining to the placement of intravenous lines. Intravenous insertions should be first documented to encourage others to sustain continuous intravenous line maintenance, such as checking the site for problems and removing any unnecessary lines or tubing as soon as appropriate. As a result of inadequate checking of IV sites and no knowledge on whether the site was checked prior due to poor documentation, this resulted in a few patients with peripheral IV’s experience IV infiltration and IV extravasation. Fluid escapes from the vein into the nearby soft tissue, causing IV infiltrations and extravasations. IV infiltration led to swelling, discomfort due to late detection and poor maintenance, but luckily the patient did not have exertional compartment syndrome and potential the amputation of the injured area. IV extravasation led to the tissue death (necrosis) of a patient’s limb. During a medical ward round, it was also noted that nursing professionals' poor hand hygiene is a clear risk factor for intravenous line contamination therefore resulting in an infection. Before inserting an IV line or putting on gloves, properly disinfecting hands will greatly decrease the risk of health care associated infections. Therefore, all practitioners must follow the proper hand decontamination procedure prior to and following any contact with insertion site. This includes washing hands with anti-microbial soap and water or decontaminating hands with an alcohol-based hand rub if your hands are contaminated with blood or other body fluids. During the medical ward round, it was reported that a patient had obtained a central line-associated blood stream infection (CLABSI). The central catheter was placed in the patient’s neck to administer medication. The main reason was due to poor adherence of the rules on hand hygiene, not cleaning the access port with the proper antiseptic agents just before each usage, not only using sterile tools to access catheters, and changing dressings in a non-aseptic manner. These actions allowed for easy access of micro-organisms from the central line into the patient’s bloodstream, but luckily the infection was successfully treated with antibiotics. 3 B. Nebulizer masks A nebulizer turns liquid medication into tiny droplets that can be inhaled through a mouthpiece or mask as an aerosol or mist. Many kinds of drugs can be administered using nebulizers. The medications and moisture release lung secretions and reduce breathing issues including wheezing. One of the main problems noted during the medical ward round was that nebulizer masks used on patients were left lying around on unclean surfaces when they were not in current use by the patient, this resulted in microorganisms attaching themselves to the masks and then entering through the patients mouth when used again. Poor cleaning of the nebulizer masks resulted in a slower recovery of the patient and an increased difficulty of breathing due to the number of microorganisms that enter through this way. It was also noted that when nurses administered nebulizer masks to patients, improper or no hand hygiene was done therefore increasing the risk of transmission of microorganisms into the patient’s respiratory tract. Additionally, no health education was given to the patients when handling the nebulizer mask therefore resulting in increased infections through nebulizer masks. During the medical ward round, it was reported that a patient who unknowingly had COVID-19 had spread it to other patients in the ward mainly due to the accelerated spread because of the use of a nebulizer mask. Nebulizer usage results in two things. The first is that they exhale more strongly than usual and frequently take in large breaths. By itself, this increases the number of particles produced. The second is that they inhale a tiny mist that is not entirely absorbed by the lung. Also, this is exhaled. Additionally, when lung mucus is loosened by a nebulizer, it may also be exhaled. This might come out as coughed-up particles. Therefore, regardless of the mechanism, the patient with COVID-19 who used a nebulizer had the risk of unintentionally infecting others. 4 Topic 4: Notifiable Diseases Hepatitis B Notifiable Disease Transmission Symptoms Diagnosis Hepatitis B is spread when blood, semen, or another bodily fluid that contains the virus enters the body of a person who is not already infected or who has not gotten the vaccine. Examples of how this could occur include sexual contact, sharing of needles, syringes, or other drug injection instruments, or transmission from mother to child during childbirth. Most people don't exhibit any symptoms when they are first infected. Some people do, however, experience acute illness with symptoms that last for several weeks. These signs and symptoms include nausea, vomiting, severe tiredness, darker urine, and jaundice. The following tests can be used to identify hepatitis B or its complications: -Blood test. Acute or chronic hepatitis B can be identified by blood testing. You can also find out if you are immune to the illness with a basic blood test. -Liver ultrasound. Transient elastography, a specialist ultrasound, can assess the extent of liver injury. -Liver biopsy. Your doctor might take a small sample of your liver for testing to screen for liver disease (liver biopsy). During this surgery, your doctor places a tiny needle into your liver and removes a small bit of liver tissue for lab testing. Primary, Secondary & Tertiary Treatment Primary- The primary objective of treatment for those infected with hepatitis B (HBV) is to prevent disease progression, especially to cirrhosis, liver failure, and hepatocellular carcinoma. The immune system is boosted by medications from the interferon family, which also help eradicate the hepatitis B virus. Pegylated interferon and interferon alpha are two examples. Secondary- Antiviral drugs reduce hepatitis B virus reproduction, hence reducing liver inflammation and injury. They are taken as a pill once a day for at least a year and frequently longer. Tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are two examples. 5 Tubercul osis The main tuberculosis carriers are airborne droplet nuclei, which have a size range of one to five microns. Infectious droplet nuclei are formed when persons with pulmonary or laryngeal TB disease cough, sneeze, shout, or sing. TB can spread from one person to another through the air. Most persons who have latent TB, or the absence of symptoms, are infected with the tuberculosis virus. A fever, weight loss, night sweats, and a cough are usually present symptoms when they do occur (which can occasionally have a bloody tint). The two types of tests used to discover TB bacterium in the body are the TB skin test (TST) and TB blood testing. It cannot establish a person's latent TB infection status (LTBI) or the stage of their TB disease. A chest x-ray and a sputum sample are two additional tests needed to evaluate whether a person has TB illness. During the physical examination, your doctor will use a stethoscope to listen to your lungs and will check your lymph nodes for oedema. The most common approach for detecting tuberculosis is still skin testing. A tiny amount of tuberculin is injected just beneath the skin on the inside of your forearm. In the following 48 to 72 hours, a doctor will inspect your arm to check for swelling where the injection was administered. Undoubtedly, you have TB infection if you have a hard, elevated red bump. Latent or active TB can be confirmed or ruled out by blood testing. These examinations assess your body's immunological response to the TB bacterium. Your doctor could request samples of your sputum, or the mucus that comes up when you cough, if the results of your chest Xray reveal that you have tuberculosis. TB drugresistant bacteria can also be discovered using sputum samples. This aids your doctor in selecting the drugs with the highest likelihood of success. Primary- You will be prescribed at least a 6month course of a combination of medicines if you are found to have active pulmonary TB, which affects your lungs and manifests as symptoms. Isoniazid and rifampicin are the standard of care, and for the first two months of the six-month therapy period, two other antibiotics (pyrazinamide and ethambutol) are also used. Secondary- Streptomycin (SM) used to be, and in some cases still is, a firstline therapeutic option. The increasing prevalence of SM resistance in various parts of the world has reduced the general utility of SM. Other drugs, such capreomycin and cyclosporine, are reserved for special situations like drug intolerance or resistance. 6 Covid-19 COVID-19 can be obtained from those who are infected with the virus. Aerosols— tiny droplets or particles that are emitted from the mouth or nose when a person with COVID-19 coughs or exhales—can transmit the illness from one person to another. Anyone within six feet of that individual can breathe it into their lungs. These droplets fall on numerous objects and surfaces all around the person. The symptoms of many COVID-19 patients are mild to moderate, and they usually go away on their own. Some people, however, will develop serious illnesses and need medical care. The most common symptoms are fever, coughing, fatigue, and a loss of taste and smell. Chest pain, shortness of breath, trouble breathing, loss of voice or movement, confusion, and disorientation are all major warning signs. You should seek immediate medical assistance if you encounter serious symptoms. To test for the COVID-19 virus, a medical expert takes a sample from the nose, throat, or saliva. The samples are then brought to a lab for examination. You could send the sputum from your cough for examination. These can only be obtained with a prescription from a doctor. A positive Nucleic Acid Amplification Test (NAAT) or antigen test is usually indicative of a person containing COVID-19, and additional testing is not usually required. Primary- If you just have minor symptoms, your doctor can recommend that you heal at home. When you are ill, it is recommended that you stay as far away from family members and pets as you can, protect them by wearing a mask, and use a different bathroom and bedroom. Additionally, regulate your home's airflow by opening windows and, when needed, using air purifiers. Secondary- Sotrovimab and Bebtelovimab are effective treatments for COVID-19 omicron variant. These treatments are given to people with mild to moderate COVID-19 who are at an increased risk of becoming seriously unwell as a result of the condition. The course of treatment includes a single intravenous infusion. For the greatest outcomes, these medications must be used as soon as COVID-19 symptoms emerge and before reaching hospitalization. Tertiary- Supportive therapy helps to reduce symptoms and may include ibuprofen or acetaminophen painkillers, cough medicine, rest, and fluid consumption. 7 Conclusion It is evident throughout this assignment that micro-organisms are widely spread throughout healthcare settings as well as from person to person. This results in a variety of diseases or viruses being spread and therefore causing further illness or possibly death if left untreated. It is important for nurses to be mindful of the harmful effects of micro-organisms that cause harm to patients health and also important for nurses to be cautious when providing care to a patient, ensuring they are not contaminating or creating an easy pathway for bacteria to enter and reach the patient. This can be seen by the actions done when administering I.V lines and nebulizers, failure to administer these devices aseptically or ensure no contamination of them results in a variety of healthcare associated infections. It is also evident that notifiable diseases described in this assignment are caused by harmful micro-organisms and can occur in healthcare settings as well. If left untreated this may result in worsened signs and symptoms, and possible death. As nurses, we always need to ensure the safety of our patients and in doing so we also ensure the safety of ourselves and other people that are involved. Microbiology also helps us as nurses identify possible treatments for when an individual has become infected due to harmful micro-organisms. These treatments are evident throughout the assignment, for both medical devices and notifiable diseases. 8 Bibliography AAAWholesaleCompany, 2020. AAAWholesaleCompany. [Online] Available at: http://site.aaawholesalecompany.com/blog/2020/01/14/3-different-types-ivs/ [Accessed 3 November 2022]. Caliendo, A. M., 2022. UpToDate. [Online] Available at: https://www.uptodate.com/contents/covid-19-diagnosis [Accessed 5 November 2022]. Clevelan Clinic, 2019. Home nebulizer. [Online] Available at: https://my.clevelandclinic.org/health/drugs/4254-homenebulizer#:~:text=A%20nebulizer%20changes%20liquid%20medicine,and%20help%20loosen%20lun g%20secretions. [Accessed 4 November 2022]. Dhir, A., 2019. Microbiology in Nursing. IJSDR, 4(6), p. 394. Frank, K., 2014. PubMed Central. 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[Online] Available at: https://www.britannica.com/science/microbiology [Accessed 3 November 2022]. Pyrsopoulos, N. T., 2022. Medscape. [Online] Available at: https://emedicine.medscape.com [Accessed 4 November 2022]. 9 World Health Organization, 2021. Coronavirus Disease. [Online] Available at: https://www.who.int/news-room/questions-and-answers/item/coronavirus-diseasecovid-19-how-is-it-transmitted [Accessed 5 November 2022]. World Health Organization, 2022. Hepatitis B. [Online] Available at: https://www.who.int [Accessed 4 November 2022]. 10 Appendices Kaitlyn Edwin 0002221808 Kaitlynedwin27@gmail.com Diploma in Nursing GNE Netcare Campus Netcare Pretoria East Hospital Sr. Marna Rautenbach IPC Assignment 12 November 2022 11