ABSTRACT The effect of El-Nino Southern Oscillation (ENSO) on rainfall characteristics over Karachi region is demostrated. This research used rainfall data collected during the period 1961-2021. The result suggest a relationship between ENSO epochs and behavior of rainfall observed in the study area, further analysis show tha ENSO factor effects parallel on rainfall like other factors such as deforestation. The study of ENSO-Rainfall cycle also focused on the relevance of numerous generalized autoregressive conditional heteroskedasticity GARCH model is suitable to analyze its behavior for estimating forecast evolution of ENSO Rainfall cycle. The GARCH(1,1) model is used for ensuring the appropriateness of autoregression conditional heteroscedasticity effect on rainfall and ENSO cycle. We take different value of autoregression and moving averages including (3,1) and (3,3) but an ARMA(6,6)-GARCH(1,1) is used most of the time. The data is observed till we achieve the convergence after specific iteration and the coefficient covariance computed using outer product of gradient.