MEDICATION RISKS
NOTES
Bad for Ears (Ototoxicity)
Antibiotics
z Gentamicin and tobramycin
z Macrolides (reversible)
Loop diuretics
z Furosemide
Chemotherapy
z Cisplatin
z Carboplatin
Bad for Liver (Hepatotoxicity)
Antihypertensives
z ACE inhibitors
Elevated liver enzymes (ALT, AST)
Normal:
z ALT: 7 - 46 units/L
z AST: 10-40 units/L
Unusual fatigue/weakness, loss of
appetite, pain in upper abdomen, darkcolored urine, yellowing of skin or eyes
Anti-infectives
z Erythromycin
z Fluconazole
z Itraconazole
ACE inhibitors
NSAIDs
Tuberculosis
z Rifampin
z INH
Psych
z Phenothiazines
Alcohol
Bad for Kidneys (Nephrotoxicity)
Antibiotics
z Gentamicin
z Amphotericin B
Pain
z Acetaminophen
z NSAIDs
WATCH FOR:
Radiocontrast media
(especially with
metformin)
Elevated BUN
Normal:
z 7 - 20 mg/dL (2.5 - 7.1 mmol/L)
Lithium salts
z Rifampin
z INH
Elevated serum creatinine
Normal:
Chemotherapy
z Cisplatin
www.lecturio.com/nursing
z Women: 0.6 - 1.1 mg/dL
z Men: 0.7 - 1.3 mg/dL
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