If the results of serum bilirubin, alkaline phosphatase, LOH and SGPT suggest
obstructive jaundice, the next best confirmatory
a. Pseudocholinesterase
b. SGPT
c. Bone marrow
• d. 5' nucleotidase
e. Protein electrophoresis
The clinical utility of enzyme analysis does not depend on
a. Specificity for substrate
• b. Long half- life in circulation
c. Specificity of organ source
d. Existence of circulating cofactors
e. Leakage from disease cells
X
Serum haptoglobin:
a. binds heme
b. is decreased in patients with tissue injury and neoplasia
c. can be separated into distinct phenotypes by starch-gel electrophoresis
• d. is increased in patients with prosthetic heart valves
Refer to the following illustration:
Patient Values Reference Values
Total protein 7.8 g/dl 6.0-8.0 g/dl
Albumin 3.0 g/dl 3.6-5.2 g/dl
Alpha- 1 0.4 g/dl 0.1-0.4 g/dl
Alpha-2 1.8 g/dl 0.4-1 .0 g/dl
Beta 0.5 gldl 0.5- 1.2 g/dl
Gamma 1.1 g/dl 0.6-1.6 gldl
• a. acute inflammation
b. polyclonal gammopathy (eg, chronic inflammation)
c. alpha- 1 -antitrypsin deficiency; severe emphysema
d. cirrhosis
)C
LOH is elevated in all of the following EXCEPT:
a. viral disease
b. Megaloblastic anemia
c. shock
• d. metastatic liver disease
e. severe lead poisoning
Refer to the following illustration:
Patient Values Reference Values
Total protein 8.5 g/dl 6.0-8.0 g/dl
Albumin 4.3 g/dl 3.6-5.2 g/dl
Alpha- 1 0.3 g/dl 0.1-0.4 g/dl
Alpha-2 0.7 g/dl 0.4- 1.0 g/dl
Beta 0.9 g/dl 0.5-1.2 g/dl
Gamma 2.3 g/dl 0.6-1.6 g/dl
The above serum protein electrophoresis pattern is consistent with:
• a. cirrhosis
b. monoclonal gammopathy
c. polyclonal gammopathy (chronic inflammation)
d. alpha- 1 -antitrypsin deficiency; severe emphysema
What enzyme may be elevated in all of these conditions: Ml, skeletal muscle disease,
pulmonary disease, CNS disease, hypothyroidism, after vigorous exercise and
intramuscular injections?
• a. CPK
b. SGOT
c. Alkaline phosphatase
d. SGPT
e. LOH
Which of the following is not an NPN substance?
a. ammonia
b . urea
c. creatinine
• d. troponins
The protein electrophoretic pattern of plasma, as compared to serum, reveals a:
• a. Fibrinogen peak between the beta and gamma globulins
b. A decreased albumin peak
c. Fibrinogen peak with the ai-globulins
d. Broad increase in the Gamma globulins
)(
1ne l,;Umne ~creenmg test ror mcreasea serum pneny1a1anine 1s oasea on:
a. A fluorometric method in which phenylalanine is reacted with ninhydrin
• b. The microbiologic procedure in which phenylalanine counteracts the
effects of a metabolic antagonist on the growth of 8. subtilis
c. The thin layer chromatography method in which identification is made by
comparison of the unknown Rf value to Rf values of the known
d. A dipstick procedure in which phenylalanine is converted to phenylpyruvic
acid is then reacted with ferric chloride
In which of the following conditions would a normal level myoglobin be expected?
• a. multiple myeloma
b.AMI
c. Crushing trauma received in a car accident
d. renal failure
What test would be significant in muscular atrophy
a. LOH
• b. creatinine
c. CPK
Patients with jaundice due to liver cell disease, compared to those with obstructive
jaundice, usually have
• a. Higher AlkaPhos,LDH and AST activity
b. Long half- life in circulation
c. Lower alkaphos, higher LDH and AST activity
ors
d. Higher Alkaphos, lower LDH and AST activity
rgan source
e. Specificity
Lower AlkaPhos,LDH and AST activity
for substrate
)C
:48 PM Wed Jan 12
•••
lens.csuandrews.net lil
~ CSU-LENS@ANDREWS
Question 15
Course Search
Marked out of
1.00
Flag
question
a. BB only
• b. MM and MB
c. MB only
d. MM MB BB
Question 16
Liver failure is not usually associated with:
Correct
Marked out of
•
Heart muscle contains which of the following CPK isoenzyme
Correct
f
'::;:' 36°/c
a. Elevated bilirubin level
1.00
f Flag
question
b. Elevated blood ammonia level
• c. High BUN level
d. Decreased serum albumin
e. Prolonged prothrombin time
nathalie taguinod
Ill
The following pattern of serum protein electrophoresis is obtained:
Albumin: decrease or normal
A1- and a2- globulins: increased
Beta and Gamma globulins: normal
This pattern is characteristic of which of the following conditions?
• a. cirrhosis
b. nephrotic syndrome
c. acute inflammation
d. gammopathy
LDH fractions 1 and 2 (LDH-1 and 2) are elevated in diseases of
a. Heart, red cells
• b. Red cells, liver brain
c. Kidney, red cells, liver
d. Heart, kidney, liver
e. Heart, lungs, brain
A total protein as assayed on serum from a patient with multiple myeloma. The result
using the Biuret method was lower than the result given by the Kjeldahl methos. This
discrepancy was due to the fact that:
a. In the Biuret method, abnormally small proteins produce a complex that has a
different shade of color than normal proteins, thus underestimating the protein
level.
0
b. The kjeldahl method measures all nitrogen containing compounds
X
including proteins and non-protein nitrogens, and thus overestimates the
protein level.
c. Hemolysis falsely elevates the Kjeldahl method but has no effect on the protein
level determined by the Biuret method.
d. because the methods are based on different principles, a comparable result is
not expected