Human immunodeficiency virus (HIV) Human immunodeficiency virus, also known as HIV, is a retrovirus that causes human immune system to fail. The virus attacks and gradually destroys the human immune system, leaving the host unprotected when infected. People who are infected with HIV and die often die from secondary infections or cancer. AIDS is the final stage of human immunodeficiency virus infection Cells that it attacked HIV virus has been proved to be a T4 lymphocytic and neurocytic virus. HIV virus enters human body blood by skin break, the target cell that main attack and destroy is T4 lymphocyte, and to get T4 cell to lose original normal immune function. The structure The human immunodeficiency virus is about 80-140 nanometers in diameter and is round or oval in shape. And it gots a p24 protein made capsid.