Dr. Mahdi Aziz – Sess 12 – Lec 2 Neonatal Intestinal Obstruction • Most common surgical emergency in neonate • Management depends on timely diagnosis • Needs radiological assessment • Outcome is excellent Presentation • Refusal to take feed • Vomiting • Abdominal distension • Delayed/failure to pass meconium Causes • High Intestinal Obstruction: • Proximal to ileum i.e., gastric, duodenal & jejunal • Low Intestinal Obstruction: • Distal ileum & colon Child care | 1 High Intestinal Obstruction 1. Gastric Atresia • Rare • Usually, distal • AXR-gas filled stomach without distal intestinal air (single bubble sign) • Can be diagnosed antenatally by US 2. Duodenal atresia • Congenital failure of recanalization • Association with VATER/VACTREL & trisomy 21 • Post. Ampullary – bilious vomiting • On AXR: (double bubble sign) ➢ gas filled distended stomach & duodenal cap ➢ Absent distal bowel gas Child care| 2 3. Duodenal stenosis • Gastro duodenal distension but distal gases present • On contrast-slow transit of contrast distally 4. Duodenal web • Small congenital obstructive membrane with central aperture 5. Malrotation & Mid gut volvulus • Failure of normal physiological herniation in embryo • Leads to narrow mesenteric attachment • Predispose to rotation around superior mesenteric vessels • If untreated leads to bowel ischemia & infarction Child care| 3 6. Jejunal Atresia • Intestinal ischemia during intra uterine life. • Present with bilous vomitting & abdominal distention. • TRIPLE BUBBLE SIGN Distention of stomach, duodenum & jejunum. Low Intestinal Obstruction 1. Ileal Atresia • Due to intra uterine ischemic insult. • Bilous vomiting & distention. Numerous dilated bowel loops. 2. Meconium Ileus • Meconium plugs obstruct colon & distal small bowel. • Associated with cystic fibrosis. • AXR- multiple distended gut loops. • Contrast study-meconium plugs & micro colon. Child care| 4 3. Functional Immaturity of Colon • Meconium plug /small left colon syndrome. • Benign & self-limiting condition. • Due to immaturity of colonic ganglion cells. • To infants of diabetic mothers & those who took MgSO4 for pre-eclampsia. Contrast studies- dilated ascending & transverse colon small descending colon rectum normal Child care| 5 4. Hirschsprung Disease • Arrest of neuron migration to distal bowel before 12 week. ➢ Rectosigmoid- 75% ➢ Splenic flexure- 20% ➢ Whole colon- 5% CLINICAL PRESENTATION ➢ Neonatal Intestinal Obstruction (NIO) ➢ Chronic Constipation (CC) ➢ Enterocolitis (EC) • Affected segment narrowed • Proximal dilatation Contrast Enema showing Aganglionic segment with the transition zone 5. Colonic Atresia • Rarely an uncommon condition • Intrauterine vascular insult • Proximal to splenic flexure 6. Anorectal Malformation • Association with VATER • High/Low depending levator ani muscle • Incidence: 1 in 5000 live births. • Most common in females is a rectovestibular fistula • 50% of all patients with anorectal malformations have an associated urogenital anomaly • The relationship of the distal rectum to the puborectalis muscle divides the imperforate anus malformations into high (supralevator) and low (infralevator) malformations Child care| 6 Early treatment for neonates born with an anorectal anomaly is crucial. During the first 24-48 hours of life, answer the following 2 questions: 1. Are any associated anomalies present that threaten the baby's life and need to be addressed immediately? 2. Should the infant undergo a primary procedure with no protective colostomy or a protective colostomy with a definitive repair at a later date? Child care| 7 Child care| 8