ACTIVE LEARNING TEMPLATE: Medication Zhejun Xuan STUDENT NAME______________________________________ buspirone MEDICATION___________________________________________________________________________ 2 REVIEW MODULE CHAPTER__week __________ CATEGORY CLASS__anxiolytics _____________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action Binds to serotonin and dopamine receptors in the brain, increases norepinephrine metabolism in the brain Therapeutic Use Used to decrease anxiety associated with anxiety disorders and the frequency of panic attacks Complications dizziness, drowsiness, headache, nervousness, insomnia, light-headedness, fatigue, numbness, excitement, confusion, depression, anger, decreased concentration, paresthesia, incoordination, tremor, hostility. Contraindications/Precautions Hypersensitivity, severe hepatic/renal impairment, concurrent use of MAOIs, breastfeeding Interactions Rifampin, dexamethasone, phenytoin, phenobarbital, carbamazepine, nefazodone, ketoconazole, itraconazole, ritonavir, erythromycin, MAOIs, grapefruit juice, Kava Kava, valerian, chamomile, alcoho Medication Administration Adult: PO 7.5–15 mg/d in divided doses, may increase by 5 mg/d q2–3d as needed (max: 60 mg/d) Geriatric: PO 5 mg b.i.d., may increase to max 60 mg/d Nursing Interventions Assess degree and manifestations of anxiety Buspirone does not appear to cause physical or psychological dependence Do not confuse buspirone with bupropion PO May be administered with food to minimize gastric irritation. Food slows but does not alter extent of absorption Client Education Evaluation of Medication Effectiveness Decrease anxiety levels; frequency of panic attacks ACTIVE LEARNING TEMPLATES Patients changing from other antianxiety agents should receive gradually decreasing doses Advise patient to avoid concurrent use of alcohol or other CNS depressants Notify health care professional if any chronic abnormal movements occur Consult provider if you paln to become pregnant or are pregnant Therapeutic Procedure A7