As we know, some medications can sometimes have uncomfortable or difficult to manage side effects. Week 6, we will be learning about elimination and alterations in elimination. For this activity, please look up 5 medications that can cause constipation and 2 medications that can cause urinary retention. Fill out the brief table below and we will share some of our findings in our discussion this afternoon. Name of medication Pharmacologic classification Why it’s commonly used Dosage for adult Ibuprofen (Motrin) NSAIDs Pain reliever or fever reducer 400-800 mg x daily (don’t exceed 3200 mg/day) Diphenhydramine (Benadryl) Antihistamines 20-50mg q 4-6 hr (don’t exceed 300mg/day) Nortriptyline (Pamelor) Tricyclic antidepressants Relief of allergic symptoms caused by histamine release Treats depression Diltiazem Calcium channel blockers Treats hypertension (blood pressure med) 30-120 mg 3-4 times daily Ditropan XL Hydralazine Anticholinergics Help with overactive bladder with symptoms of urge incontinence (treat incontinence) Antihypertensive Treat moderate to severe hypertension 25 mg 3-4 times daily up to 150 mg/day Don’t exceed 240 mg/day 5 mg 2-3 times daily (don’t exceed 5mg/4times daily) 10 mg 4 times daily Side effects besides constipation/urinary retention Headache, GI bleeding, hepatitis, dyspepsia, n/v and abdominal discomfort, cystitis, hematuria, renal failure, hypersensitivity reactions Hypotension, anorexia, drowsiness, constipation Hypotension, arrhythmias, blurred vision, dry eyes, nausea n/d, n/d, upset stomach and stomach pain, chest pain, edema, dry mouth, dizziness, drowsiness Tachycardia, angina, arrhythmias, edema, orthostatic hypotension, d/n/v, rash, arthralgias, arthritis, dizziness, drowsiness, headache, peripheral neuropathy, drug- Diphenhydramine (Benadryl) Antihistamines Relief of allergic symptoms caused by histamine release 20-50mg q 4-6 hr (don’t exceed 300mg/day) induced lupus syndrome Hypotension, anorexia, drowsiness, constipation