1 Vaccine-Preventable Diseases: Measles, Mumps, Rubella, and Chicken Pox (Varicella) Sofia Mannucci Department of Nursing, Lone Star College - Cy-Fair RSNG 1309-5001: Introduction to Nursing Dr. Keck, Professor Valdez, Professor Reed March 29, 2023 2 Vaccine-Preventable Diseases: Measles, Mumps, Rubella, and Chicken Pox (Varicella) In South America, a study performed by the University of Antioquia in Colombia revealed that “the number of deaths and the adjusted rates decreased since 1989 in all diseases” (Arango- Úsuga et al., 2022) within populations that received vaccinations. Vaccine-preventable diseases (VPDs) have been researched thoroughly in order to develop high standards of care and prevention. Multiple prevention strategies and standards of care exist for different diseases and following them help individuals live a healthier day-to-day life. These standards are promoted by public health agencies, and they encourage citizens to follow proper hygiene and receive vaccinations in order to prevent the spread of these illnesses. Vaccine-preventable diseases are conditions that can be prevented by the administration of a vaccine. Measles, mumps, rubella, and chickenpox (varicella) are some of the most common vaccine-preventable diseases. Measles is a highly contagious virus that “spreads through the air when a person coughs or sneezes” (Centers for Disease Control and Prevention [CDC], 2021b). Signs and symptoms include red eyes, fever, runny nose, cough, and a small rash. Mumps is a virus transmitted through direct contact with respiratory droplets or saliva. It is characterized by “fever, headache, muscle aches, tiredness, and loss of appetite. Then, most people will have swelling of their salivary glands (often referred to as parotitis when the parotid gland, in front and below the ear, swells). This is what causes the puffy cheeks and a tender, swollen jaw” (CDC, 2021d). Rubella, also known as German Measles, and Three-Day Measles, is a contagious virus that is transmitted through inhaling secretions from sneezes or coughs, and through pregnancy from an infected mom to her fetus (CDC, 2020c). Rubella presents as a mild illness with fever, sore throat, headache, and discomfort. In a pregnant woman who is infected, it “can cause a miscarriage or serious birth defects in an unborn baby” (CDC, 2021a). Lastly, 3 chickenpox (varicella) is caused by a highly contagious virus, called varicella-zoster virus, that is transmitted through “direct contact, inhalation of aerosols from vesicular fluid of skin lesions of acute varicella or zoster, and possibly through infected respiratory secretions that also may be aerosolized” (CDC, 2022c). Chickenpox causes an itchy, blister-like rash on the upper trunk and face, and then spreads to other areas of the body. The most effective method of preventing vaccine-preventable diseases is through the administration of immunizations. Not only do immunizations help an individual stay protected from catching a disease, but they also minimize the spread of the disease, and reduce the severity of symptoms of those who are infected. The best method for preventing the acquisition of measles, mumps, and rubella, is through receiving the MMR (measles-mumps-rubella) or MMRV (measles-mumps-rubella-varicella) vaccines. According to the Centers for Disease Control and Prevention (2020a), the MMR vaccine is a 3-in-1 combination that stimulates immunity for all three diseases, preventing the spread of it. This vaccine is deemed as safe, with minimal side effects that include sore arm, fever, mild rash, and temporary discomfort. The MMRV vaccine is a 4-in-1 combination effective against measles, mumps, and rubella, and chickenpox (varicella). This vaccine has mild side effects including sore arm, fever, and a mild rash. In rare cases, it may cause febrile seizures in children (CDC, 2020b). The standard of prevention for varicella is through immunization against the varicella-zoster virus. There are two vaccines available, the chickenpox vaccine (most commonly distributed), and the MMRV vaccine previously mentioned. The side effects for either vaccine are minor and include sore arm, fever, and a mild rash (CDC, 2020b). Although, immunizations are the key in preventing sickness from any of these vaccine-preventable diseases, other crucial methods of precautions 4 against acquiring vaccine-preventable diseases include frequent handwashing, and avoiding contact with those infected, or those suspected of being infected. The current recommendation for standards of care against measles, mumps, and rubella is for children to “get two doses of MMR vaccine, starting with the first dose at 12 through 15 months of age, and the second dose at 4 through 6 years of age” (CDC, 2021b), two doses have proven to be 97% effective against acquiring measles. Receiving one dose of the MMRV vaccine is a second option available for prevention of measles for children between the one and twelve years of age. However, the MMRV vaccine should not be given to “anyone who has ever had a life-threatening allergic reaction to the antibiotic neomycin, or any other component of MMR vaccine” (CDC, 2020b) due to the high chances of a fatal allergic reaction. The current standard for prevention of chicken pox (varicella) is to administer two doses of the vaccine to “children, adolescents, and adults who have never had chickenpox and were never vaccinated. Children are routinely recommended to receive the first dose at 12 through 15 months of age and the second dose at 4 through 6 years of age” (CDC, 2021e). The MMRR vaccine is another option to prevent varicella and can be administered to children between the ages of 1 and 12 years. In addition to the prevention of varicella, there is also an option to get the chickenpox vaccine after exposure to the virus. This may help prevent the disease or lessen the symptoms and spread to others. The chicken pox vaccine is contraindicated in those who have gotten the disease in the past and have the antibodies, and those who are immunocompromised (CDC, 2021e). The Centers for Disease Control and Prevention (CDC) hope to help globalize vaccine access and administration in order to eradicate vaccine-preventable diseases. In order to achieve this, they focus on five main goals: Prevent VPDs by strengthening immunization services, detect VPDs by supporting and improving disease surveillance systems, respond to and prepare 5 for VPD outbreaks, sustain immunization program capacities over time, and innovate to increase immunization program impact through research and evaluation (CDC, 2022a). These goals are achieved with the help of the STOP program: “a collaboration between CDC, the World Health Organization (WHO), and the United Nations Children’s Fund (UNICEF), to train international public health consultants to deploy to countries worldwide. STOP consultants help strengthen national immunization surveillance programs, support supplemental immunization activities, respond to disease outbreaks” (CDC, 2022b). Other global promotions include holidays dedicated to personal hygiene. According to Dr. David Merendes (2018), “Global Handwashing Day is celebrated annually on October 15 to promote handwashing with soap as an easy and affordable way to prevent disease in communities around the world”. This teaches the importance of handwashing and how it keeps humans healthy and prevents illness. Despite the effectiveness of immunizations for vaccine-preventable diseases, society today challenges every aspect of research against vaccinations for vaccine-preventable diseases. It is crucial to understand and teach the science behind immunizations and why it is safer to follow the recommended standards of prevention, rather than risking it and getting infected. 6 References Arango-Úsuga, C., Ochoa, J., León, A., & Hincapié-Palacio, D. (2022). Historical trends in mortality from “older” vaccine-preventable diseases, Colombia: implications for elimination and control. Public Health (Elsevier), 213, 157–162. https://web-s-ebscohostcom.lscsproxy.lonestar.edu/ehost/detail/detail?vid=3&sid=523982a8-12c7-4295-b505e7c56d441154%40redis&bdata=JkF1dGhUeXBlPWlwLGNwaWQmY3VzdGlkPXMxMD g4NDM1JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#AN=160580934&db=a9h Centers for Disease Control and Prevention. (2020a, September 9). Measles, Mumps, Rubella (MMR) Vaccine. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/vaccinesafety/vaccines/mmr-vaccine.html Centers for Disease Control and Prevention. (2020b, September 9). Safety Information for Measles, Mumps, Rubella, Varicella Vaccines. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/vaccinesafety/vaccines/mmrvvaccine.html Centers for Disease Control and Prevention. (2020c, December 31). Rubella Transmission. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/rubella/about/transmission.html Centers for Disease Control and Prevention. (2021a, January 26). About Rubella (German Measles) Vaccination. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/vaccines/vpd/rubella/index.html 7 Centers for Disease Control and Prevention. (2021b, January 26). Measles Vaccination. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/vaccines/vpd/measles/index.html Centers for Disease Control and Prevention. (2021c, January 26). Mumps Vaccination. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/vaccines/vpd/mumps/index.html Centers for Disease Control and Prevention. (2021d, March 8). Mumps. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/mumps/hcp.html#:~:text=or%20congregate%20settings.,Transmission,with%20someone%20who%20has%20mumps. Centers for Disease Control and Prevention. (2021e, April 28). Chickenpox Vaccination: What Everyone Should Know. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/vaccines/vpd/varicella/public/index.html Centers for Disease Control and Prevention. (2022a, January 6). CDC Global Immunization Strategic Framework. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/globalhealth/immunization/framework/index.html Centers for Disease Control and Prevention. (2022b, April 26). STOP Program. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/globalhealth/immunization/stop/index.html 8 Centers for Disease Control and Prevention. (2022c, October 21). Chickenpox (Varicella) for Healthcare Professionals. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://www.cdc.gov/chickenpox/hcp/index.html#:~:text=this%20is%20limited.,Transmission,that%20also%20may%20be%20aerosolized. Merendes, D. M. (2018, October 15). 3 Reasons Why Handwashing Should Matter to You. Centers for Disease Control and Prevention. Retrieved March 26, 2023, from https://blogs.cdc.gov/publichealthmatters/2018/10/handwashing-matters/