Common Laboratory Reference Intervals Laboratory Test *Activated partial thromboplastin time (aPTT) Conventional Units (SI Units) 30-40 sec (30-40 sec) For those receiving anticoagulant therapy, aPTT is 1.5–2.5 times control value in seconds. Alanine aminotransferase (ALT; formerly known as serum glutamate pyruvate transferase [SGPT]) 4-36 U/L (4-36 U/L) Albumin 3.5-5.0 g/dL (35-50 g/L) Ammonia 10–80 mcg/dL (6–47 mcmol/L) Amylase Aspartate aminotransferase (AST) (formerly known as serum glutamic oxaloacetic transferase [SGOT]) 60–120 Somogyi units/dL (100–300 U/L) Bilirubin 0-35 U/L (0-35 U/L) Total: 0.3 - 1.0 mg/dL (5.1 - 17 mcmol/L) Indirect: 0.2 - 0.8 mg/dL (3.4 - 12 mcmol/L) Direct: 0.1 - 0.3 mg/dL (1.7 - 5.1 mcmol/L) Blood culture No growth Bacteremia: Bacteria growing in the blood can often be grown in the culture medium in the microbiology laboratory. When bacteremia is suspected, antibiotics should be started immediately after blood cultures are obtained. *Blood gases – arterial and venous values Arterial pH 7.35-7.45 (7.35-7.45) Venous pH 7.31-7.41 (7.31-7.41) PaCO2 35-45 mm Hg (35-45 mm Hg) Arterial PaO2 80-100 mm Hg (80-100 mm Hg) Venous PvO2 40-50 mm Hg (40-50 mm Hg) Bicarbonate 21-28 mEq/L (21-28 mmol/L) *Blood urea nitrogen (BUN) 10 - 20 mg/dL (3.6 - 7.1 mmol/L) Calcium 9-10.5 mg/dL (2.25-2.75 mmol/L) Cerebrospinal fluid (CSF) Lumbar Protein: 15-45 mg/dL (0.15-0.45 g/L) Glucose: 50-75 mg/dL (2.8-4.2 mmol/L) WBCs (white blood cells): 0-5 cells/mcL (0-5 × 106/L) RBCs (red blood cells): negative (negative) Chloride: 116–122 mEq/L of CSF (116–122 mmol/L of CSF) Pressure: <20 cm H2O (<20 cm H2O) Chloride 98-106 mEq/L (98-106 mmol/L) *Cholesterol <200 mg/dL (<5 mmol/L) age dependent Note: see below for low density lipoprotein (LDL), high density lipoprotein (HDL), and triglyceride levels Creatine kinase (CK) Male: 55-170 U/L (55-170 U/L) Female: 30-135 U/L (30-135 U/L) Creatine kinase isozyme of heart male: 2 -6 ng/mL (2 - 6 mcg/L) CK-MB (CK-2) female: 2 - 5 ng/mL (2 - 5 mcg/L) *Creatinine male, 0.6-1.2 mg/dL (53-106 mcmol/L) female 0.5-1.1 mg/dL (44-97 mcmol/L) D-dimer <50 ng/mL (<3.0 mmol/L) Erythrocyte sedimentation rate (ESR), Westergren Male: ≤15 mm/hr (≤15 mm/hr) Female: ≤20 mm/hr (≤20 mm/hr) Ferritin (serum) Male: 12-300 ng/mL (12-300 ng/L) Female: 10-150 ng/mL (10-150 ng/L) Fibrinogen 60-100 mg/dL (2.0–5.0 g/L) *Glucose, fasting 70-99 mg/dL (3.9-5.5 mmol/L) Glomerular filtration rate (GFR) >60 mL/min/1.73 m2 (age dependent) High density lipoprotein (HDL) >60 mg/dL (>1.55 mmol/L) *Hematocrit (altitude dependent) Male: 42-52% (0.42-0.52 volume fraction) Female: 37-47% (0.37-0.47 volume fraction) *Hemoglobin (altitude dependent) Male: 14-18 g/dL (140-180 mmol/L) Female: 12-16 g/dL (120-160 mmol/L) *Hemoglobin, glycosylated or glycated (HbA1c [A1c]) <6% (adult without diabetes) Homocysteine (dependent on gender and age) 4.5 -11.9 mcmol/L (4.5 -11.9 mcmol/L) *International normalized ratio (INR) 0.81-1.2 (0.81-1.2) Lactic acid (venous) 5–20 mg/dL (0.6–2.2 mmol/L) Low density lipoprotein (LDL) <100 mg/dL (<2.59 mmol/L) Lipase 0 – 160 U/L (0 – 160 U/L) Magnesium 1.8–2.6 mEq/L (0.74–1.07 mmol/L) Myoglobin <90 ng/mL (1.0–5.3 nmol/L) B-type natriuretic peptide <100 ng/mL (<100 mcg/L) Arterial: 95%-100% (95%-100%) Venous: 60%-80% (60%-80%) Oxygen Saturation Phosphatase alkaline (ALP) 38-126 U/L (0.65-2.14 µkat/L) Phosphorus, phosphate 3.0-4.5 mg/dL (0.97-1.45 mmol/L) *Platelets 150,000-400,000/mm3 (150-400 × 109/L) *Potassium 3.5-5.0 mEq/L (3.5-5.0 mmol/L) Protein Total 6.4-8.3 g/dL (64-83 g/dL) Prothrombin time (Protime, PT) 11-12.5 sec (11-12.5 sec) For those receiving anticoagulant therapy, PT is 1.5–2.0 times control value in seconds. Red blood cells Male: 4.7–6.2 × 1012/L (4.7–6.2 × 1012/L) Female: 4.2–5.4 × 1012/L (4.2–5.4 × 1012/L) *Sodium 135-145 mEq/L (135-145 mmol/L) Specific gravity urine, Random 1.003-1.030 (same as conventional units) Thyroid stimulating hormone (TSH) 2–10 mcIU/mL (2–10 Miu/L) Thyroxine (T4), total 5–12 mcg/dL (64–154 nmol/L) Thyroxine (T4), free Triglycerides 0.8–2.8 ng/dL (10–36 pmol/L) Female:35-135 mg/dL (0.40-1.52 mmol/L) Male: 40-160 mg/dL (0.45-1.81 mmol/L) Troponin Uric acid A troponin value of 0.05 to 0.49 ng/mL is considered indeterminate; a value greater than 0.50 ng/mL indicates a strong probability of acute myocardial infarction. Male: 4.0-8.5 mg/dL (240-501 mcmol/L) Female: 2.7-7.3 mg/dL (160-430 mcmol/L) Urine bilirubin, glucose, hemoglobin negative Ph 4.0-8.0 protein 0-trace specific gravity 1.003-1.030 Vitamin D (Total 25-hydroxyvitamin D) 30–80 ng/mL (75–200 nmol/L) *White blood cell (WBC) count 5000-10,000/mm3 (5-10 × 109/L) Segmented Neutrophils 62-68% (2.5-7.5 × 109/L) Band Neutrophils 0-9% (0-1 × 109/L) Lymphocytes 1000-4000/mm3 - 20-40% (0.1-0.4 × 109/L) Monocytes 100-700/mm3 - 2-8% (0.1-0.7 × 109/L) Eosinophils 50-100/mm3 - 1-4% (0.00-0.5 × 109/L) Basophils 15-50/mm3 - 0.5-1% (0.02-0.05 × 109/L) Note: Laboratory values may vary with different techniques and in different laboratories. Note: In the table, *Indicates the need to know laboratory values as specified in: NCLEX-RN® Examination: Test Plan for the National Council Licensure Examination for Registered Nurses (Effective April 2019), Chicago: National Council of State Boards of Nursing, Inc. (NCSBN). References: Ignatavicius, D., Workman, M., Rebar, C., Heimgartner, N. (2021). Concepts for interprofessional collaborative care (10th ed.). St. Louis, MO: Saunders. Lewis et.al (2019), Medical-Surgical Nursing in Canada: Assessment and Management of clinical problems (10th ed.), St. Louis: Elsevier. Appendix B Laboratory Values, Adapted by Jana Lok. Lewis et.al (2017), Medical-Surgical Nursing: Assessment and Management of clinical problems (10th ed.), St. Louis: Elsevier. Appendix C Laboratory Reference Intervals. National Council of State Boards of Nursing (2018), NCLEX-RN® Examination: Test Plan for the National Council Licensure Examination for Registered Nurses (Effective April 2019), Chicago: National Council of State Boards of Nursing, Inc. (NCSBN). Pagana, K., Pagana, T., Pike-MacDonald, S. (2019) Mosby’s Canadian manual of diagnostic and laboratory tests, (2nd Canadian ed.) St. Louis: Elsevier (Canadian Editor, Sandra A. Pike-MacDonald). Copyright © 2020, 2019 by Saunders, an imprint of Elsevier Inc.