GCSE Biology Biology topic 3 (Infection and response) – Higher tier Time: 30 minutes Name Set 10Y1 Bi Raw score / 30 Teacher Miss Smith Grade region Date: Q1 Q2 Q3 Q4 Q5 White blood cells Antibiotic resistance Plant disease Plant disease identification Monoclonal antibodies Pupil feedback 1 2 1 1 1 2 1 2 3 2 3 4 3 3 4 2 3 5 4 4 6 5 5 7 8 7 7 8 6 6 Q1. The body’s immune system protects us from diseases. Describe the different ways in which white blood cells protect us from infectious diseases. _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ _______________________________________________________________________ (Total 4 marks) Q2. The table shows changes in resistance to the antibiotic penicillin in one species of bacterium between 1991 and 1996. Years Percentage of cases where bacteria were resistant to penicillin 1991 – 92 7 1993 – 94 14 1995 – 96 22 A doctor was asked to treat a patient who had a sore throat. (i) How does penicillin help to treat infection? ___________________________________________________________________ (1) (ii) Use the data in the table to suggest why the doctor should not prescribe penicillin. ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ (2) (Total 3 marks) Q3. Tobacco mosaic virus (TMV) is a disease affecting plants. The diagram below shows a leaf infected with TMV. © Nigel Cattlin/Visuals Unlimited/Getty Images (a) All tools should be washed in disinfectant after using them on plants infected with TMV. Suggest why. ___________________________________________________________________ ___________________________________________________________________ (1) (b) Scientists produced a single plant that contained a TMV-resistant gene. Suggest how scientists can use this plant to produce many plants with the TMV-resistant gene. ___________________________________________________________________ ___________________________________________________________________ (1) (c) Some plants produce fruits which contain glucose. Describe how you would test for the presence of glucose in fruit. ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ (2) (d) TMV can cause plants to produce less chlorophyll. This causes leaf discoloration. Explain why plants with TMV have stunted growth. ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ (4) (Total 8 marks) Q4. A gardener is looking at the plants in his greenhouse. (a) Some of the plants have a disease. Give two ways the gardener could identify the pathogen infecting the plants. 1. _________________________________________________________________ ___________________________________________________________________ 2. _________________________________________________________________ ___________________________________________________________________ (2) (b) Plants can become unhealthy if they do not have essential mineral ions. Describe the appearance of plants with: • nitrate deficiency • magnesium deficiency. Nitrate deficiency ____________________________________________________ ___________________________________________________________________ Magnesium deficiency ________________________________________________ ___________________________________________________________________ (2) (c) Plants need other mineral ions. • Potassium ions are needed for healthy root growth. • Phosphate ions are needed for healthy flowers and fruits. The gardener makes his own garden compost. The percentage (%) of minerals in his compost was compared with two fertilisers he could buy. The data are shown in the table below. Percentage (%) mineral content Nitrate ions Phosphate ions Potassium ions Cost in £ / kg Garden compost 0.5 0.3 0.8 0.00 Fertiliser S 5.0 1.3 6.6 4.99 Fertiliser T 3.0 12.0 6.0 9.99 The gardener buys Fertiliser S. Explain why he chose Fertiliser S. ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ (4) (Total 8 marks) Q5. Monoclonal antibodies are used to measure the levels of hormones in the blood. Pregnant women produce the hormone HCG. HCG is excreted in urine. Figure 1 shows four pregnancy test strips. Figure 1 (a) Which test strip shows a negative test result? Tick one box. A B C D (1) (b) Monoclonal antibodies are used for pregnancy testing. Give one other use of monoclonal antibodies. ___________________________________________________________________ (1) (c) Figure 2 shows the parts of a pregnancy test strip. Figure 2 The pregnancy test strip will show a positive test result when a woman is pregnant. Explain how the pregnancy test strip works to show a positive result. ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ (6) (Total 8 marks)