Mendel’s Laws: Patterns of Inheritance Introduction • Attempts to explain inheritance date back at least to the ancient Greek physician Hippocrates. He suggested that particles called “pangenes” travel from each part of an organism’s body to the eggs or sperm and then are passed to the next generation. 01 • Objectives • • Variations on Mendel’s Laws • The Chromosomal Basis of • Inheritance Sex Chromosomes and SexLinked Genes BEFORE WE START DO YOU KNOW WHAT HEREDITY MEANS? The transmission of traits (inherited features) from one generation to the next. The field of genetics, began in the 1860’s, when an Augustinian named Gregor Mendel deduced the fundamental principles of genetics by breeding garden peas. Genes, retain their individuality generation after Mendel probably chose to study garden peas because they had short generation times, produced large numbers of offspring from each mating, and came in many readily distinguishable varieties. • Hmmm, Mendel. A heritable feature that varies among individuals within a population, such as flower color in pea plants or eye color in humans. A variant of a character found within a population, such as purple or white flowers in pea plants. The offspring of two different varieties are called hybrid. The cross-fertilization itself is referred to as a hybridization, or simply a genetic cross The true-breeding parents are called the “P” generation (P for parental) Their hybrid offspring are called the generation F1 (F for filial) When plants self-fertilize or fertilize each other, their offspring are the F2 generation. • • • • • CLASS OBJECTIVES Understand Mendel’s first and second laws and how they apply to the heredity patterns Mendel observed in pea plants. Understand the term allele and the relationship between dominant and recessive alleles. Know the difference between monohybrid and dihybrid crosses. Understand the link between genotype and phenotype. Understand the difference between a character and a trait. VOCABULARY Develop the following words, using the correct meaning and Illustrate 10 of them (each illustration should have a title) 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. Heredity Dominant Allele Recessive Allele Probability Genotype Phenotype Quantity Factor Experiment Genetics Traits DNA RNA 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. Genes Punnet Square Chromosomes Variations Mitosis Meiosis Chromatids Cells Replications Somatic Cell Sex-Linked Genes Mutations Meiosis and Crossing Over Chromosomes are matched in homologous pairs In humans, a typical body cell, called a somatic cell, has 46 chromosomes. Chromosomes undergoing mitosis are condensed enough to be viewed with a microscope and arranged into matching pairs HOMOLOGOUS CHROMOSOMES Two chromosomes in a pair – normally one inherited from the mother and one from the father. Using a testcross to determine genotype Testcross: The mating between an individual of unknown genotype for particular character and an individual that is homozygous recessive for that same character. Suppose you have a chocolate Lab. Referring to Figure 9.5B, you can tell that its genotype must be bb. But what if you had a black Lab? It could have one of two possible genotypes—BB or Bb—and there is no way to tell simply by looking at the dog Variations on Mendel’s Laws