🧠A.2 The human brain Most of the neural tube becomes the spinal cord but the anterior end expands and develops into the brain in the process called cephalisation (the development of a head). Brain as the central control center: directly — from cranial nerves, indirectly — spinal cord and signal molecules in blood. The advantage of having a brain is that communication between the bilions of neurons can be more rapid than it would be if control centers were more dispersed. Nervous system: Peripheral (PNS) — nerves and sensory receptors that belong to two parts: the voluntary and autonomic nervous systems. *nerves and sensory receptors in the autonomic nervous system use centers located in the medulla oblongata (which is located in the brainstem so it is the CNS) Central (CNS) — the brain (anterior part of the neural tube) and the spinal cord (the rest of the neural tube that thickens) Cell proliferation continues in the neural tube because much more neurons are needed than there are present initially. Parts of the brain Function Medulla oblongata (covered with cranial nerves) Autonomic control of the gut muscles, breathing, blood vessels and heart muscle (sympathetic & parasympathetic nerve fibres); *the pupil reflex and brain damage Cerebellum Coordinates unconscious functions such as posture, nonvoluntary movement, balance Hypothalamus Interface between the brain and the pituitary gland, controlling the secretion of the pituitary hormones Pituitary gland Secretes at least ten hormones that regulate many body functions Cerebral hemispheres (include frontal lobe, parietal Act as integrating center for higher order functions such as learning, memory, emotions. Structure: somatosensory cortex; motor cortex; visual cortex; Broca’s area; nucleus accumbens A.2 The human brain 1 lobe, occipital lobe, temporal lobe) Somatosensory cortex Receives sensory inputs Motor cortex Controls voluntary muscle contractions by striated muscles Visual cortex Processes visual stimuli detected by light-sensitive rod and cone cells in the retina Broca’s area A part of the left cerebral hemisphere that controls the production of speech Nucleus accumbens Pleasure or reward centers which receive dopamine released in responce to a variety of stimuli Methods of brain research: Lesions and autopsy Dissection of an animal or a human after death to relate positions of lesions to observed changes in behaviour or capabilities Animal experiments Carried out by removing parts of the skull to allow access to the brain and study the effects of local simulation on specific parts of the brain Functional MRI (Magnetic resonance imaging) Helps to investigate the internal structure of the body, including looking for tumours or other abnormalities 💡 The left cerebral hemisphere controls muscle activity in the right side of the body and vice versa for the right hemisphere. Brain metabolism requires large energy inputs — 10-20% of the energy consumed by basal metabolism. A.2 The human brain 2