text twinkl.com twinkl.com twinkl.com twinkl.com twinkl.com twinkl.com The antibiotic kills the rest of the non-resistant bacteria so the person may start to feel a little better. The resistant bacterium has survived the antibiotic and continues to multiply. twinkl.com There is variation in the bacterial population. One bacterium develops a mutation by chance that means it is resistant to an antibiotic. twinkl.com One strain of the bacteria has been killed, but the new strain is not affected by the new antibiotic. It survives and reproduces. This strain is resistant to multiple antibiotics, it will spread quickly because nobody is immune to it. twinkl.com The antibiotic kills some of the bacteria, the resistant bacterium survives and reproduces. twinkl.com The doctors prescribe a new antibiotic. It kills most of the bacteria, but the newly resistant strain survives and multiplies. It no longer needs to compete for resources with the older strain. twinkl.com The resistant bacterium has multiplied, they no longer have competition from the other bacteria. The person is likely to feel ill again. This time the antibiotic won’t work. One bacterium develops a random mutation which means it is resistant to another antibiotic. twinkl.com