EVALUATION OF CHRONIC RHINOSINUSITIS • Chronic rhinosinusitis (CRS) is a common disease that affects>10% of adult population . It has been delineated phenotypically into CRS without nasal polyps and CRS with nasal polyps. Both have a high disease burden and an overlapping spectrum of symptoms such as nasal obstruction, olfactory dysfunction, facial pain, pressure, and nasal discharge. Primary assessment includes evaluation of patient symptoms and impact on quality of life, nasal endoscopic examination, and imaging. • Rhinosinusitis can be defined as acute or chronic based on duration of symptoms: acute being less than 12 weeks duration and chronic being greater. • The European position paper on rhinosinusitis and nasal polyps (EPOS) has now defined rhinosinusitis as a diagnosis made on clinical grounds based on the presence of characteristic symptoms, combined with objective evidence of mucosal inflammation (Table 94.1). • Once a diagnosis of CRS has been made, assessment should consider whether this is primary CRS (that is chronic inflammation originating in and limited to the paranasal sinuses) or secondary CRS, occurring as part of multisystem disease (eg, as a manifestation of autoimmune diseases or immunodeficiency • Clinical history is focused on the duration, frequency, and severity of sinonasal symptoms and their impact on quality of life (QOL) and ability to perform normal daily activities. • Evaluation of a patient’s history should consider comorbid conditions such as allergic rhinitis and lower respiratory disease such as asthma and bronchiectasis, and the control of disease, as this is important in guiding therapy.4 Nonsteroidal anti-inflammatory drug (NSAID)induced congestion or wheeze should also be determined. • NASAL OBSTRUCTION *Duration* ..acute or chronic rhinitis • LATERALITY* Ask the patient Whether the nasal obstruction is unilateral or bilateral or changes side? • Unilateral due to mass,polyp,DNS • Bilateral due to conditions like nasal allergy, septal haematoma or ethmoidal polyposis. • *LATENCY* It should be asked whether the symptom is constant or intermittent.. Constant due to some mass • Intermittent due to some allergy • SEVERITY..prevent routine work, progressive in case of polyps or malignancy • NASAL discharge; • Nature of discharge • Allergic has thin Copious • Bacterial has thick scanty mucopurulent discharge from the middle meatus or oedema, • The hallmark of AFRS is the presence of allergic mucin. Grossly, it is thick, tenacious and highly viscous in consistency.18 Hence, the terms ‘peanut butter’ and ‘axle-grease’ are often used to describe the characteristic appearance of the mucus. • Inspection • ANTERIOR RHINOSCOPY • Structures to be seen in A/R • Nasal vestibule • Nasal septum • Colour of the mucosa • Lateral nasal wall • Inferior turbinate • Middle turbinate • Inferior meatus • Middle meatus • Nasal floor • Nasal roof (usually not seen). F • Colour of nasal mucosa Pink—Normal Bright red—Infection Bluish, wetty—Nasal allergy • • Lateral wall • Inferior turbinate: It may get hypertrophied in nasal and sinus infections. It may get enlarged, wetty and bluish in allergic nasal conditions. • • Inferior meatus: This is not easily visible unless vasoconstrictor spray is used. . Naso-lacrimal duct opens into it. • • Middle turbinate: This is the second largest turbinate in the nose and one has to extend the neck of the patient to have a better view of the turbinate. • • Middle meatus: It lies below middle turbinate. All anterior group of sinuses, i.e. Frontal, maxillary, anterior and middle ethmoidal open into the middle meatus and hence is the common site where from pus may be seen trickling down. Look for polyp in this area. • • Superior turbinate: This is usually not seen in A/R examination. One should not attempt to see superior turbinate except when patient is under general anaesthesia. • • Nasal floor: It should be looked for secretions, FB, antrochoanal polyp or malignancy. • • Nasal roof: Examination of nasal roof is painful and hence should be done under GA if needed. Abnormalities that are commonly encountered in anterior rhinoscopy are nasal secretions, nasal mass, foreign body, hypertrophy or atrophy of turbinates. • SINUS TENDERNESS Tenderness over sinuses may be elicited as follows: 1. Maxillary sinus: firm pressure is given over canine fossa. 2. Ethmoid sinus: pressure given medial to medial canthus. 3. Frontal sinus: pressure given at the roof of orbit, above medial canthus, in the floor of frontal sinus. 4. Sphenoid sinus: tenderness cannot be elicited. Sinus tenderness indicates infective pathology in affected sinus. • Nasal endoscopy is invaluable in the assessment of CRS and can informdiagnosisaswellasresponsetotherapy.Itisasimpleandwelltolerated part of the examination; local decongestion and anesthesia can be helpful but is often not required depending on the patient.10 Endoscopic evaluation of the nasal cavity provides important information on the status of the nasal mucosa (ie, edema or crusting), nasal discharge, anatomical abnormalities (eg, septal deviation, turbinate hypertrophy), evidence of visible obstruction of the nasal airway or ostiomeatal complex, evidence of previous surgery or adhesions in addition to allowing differentiation of the major phenotypical subgroups, based on the presence or absence of nasal polyps, which is often used to help inform treatment decisions in lieu of more detailed endotyping • Endoscopy scoring. Endoscopy is particularly attractive for repeated assessments over time. There are a number of endoscopic scoring systems that have been described and used in CRS. The most common is the Lund-Kennedy Endoscopy Scale, which rates each sinus for edema, discharge, nasal polyps, crusting, and scarring to arrive at total score from 0 to 20 • Imaging is an important tool in CRS, used to confirm the diagnosis when endoscopy is equivocal, assess the severity or extent of disease, and guide treatment decisions. CT is the gold standard investigation for CRSwNP, usually without contrast.. • Description of disease burden on CT-based assessment is one objective method to assess disease severity. This typically includes a quantification of the opacification of individual sinuses and an overall total score. The LMS is the most commonly used of these systems due to its simplicity and reproducibility, and it assigns a “0” for no involvement, “1” for some opacification, and “2” for complete opacification of each of the 5 sinus groups on either side, with an additional score for the ostiomeatal complex as unobstructed “0” or obstructed “2” (giving a total range 0-24