Discipline –Adult Health Nursing( ACN 1) Topic - Meningitis Submitted To, MS. Zarnigar Associate Prof. Nursing Department Superior University Lahore Submitted By, Misbah Arshad Amina Iqbal Sitara Hussain B Sc. Post RN 1st Year 1st Semester (2022-2024) Dated: 10-03-2023 1 Sr No. Content Page No. 1 Objectives 03 2 Introdution of Meningitis 04 3 Definition 05 4 Types of Meningitis 06 5 Causes 07 6 Risk Factor 08 7 Pathophysiology 09 8 Etiology and Epidemiology 10 9 Diagnosis 12-13 10 Sign and Symptoms of Meningitis 14 11 Complication 15 12 New Biomarker 16 13 Management 17 14 Treatment 18 15 Nursing Management 19 16 Prevention 20 17 Nursing Care Plan 21,22,23 18 Summary 24 19 References 25 2 Objectives General objective : At the end of this assignement we will be able to gain in depth knowledge of Meningitis. Specific objectives: At the end of this assignement the students will be able to Define of meningitis Discuss the incident rate of Meningitis Understand the pathophysiology and risk factor Elaborate the types and causes of Meningitis Evaluate the sign and symptoms Describe the Diagnostic Prevention of Meningitis 3 Introdution of Meningitis Meningitis is inflammation of the membrane that cover the brain and spinal cord. Caused by viral and bacterial infection . Viral Meningitis is less sever and clear up with specific treatment Bacterial Meningitis can be quite sever and may result in brain damage , hearing loss, or learning disabilities . 1990s type B Infleunza (Hib) was the leading cause of bacterial meningitis The Hib vaccine is given to all children as part of their immunization routine . 4 Meningitis DEFINATION: Meningitis is inflammation of meninges , which cover and protect the brain and spinal cord. The three major caused of meningitis are : (1) bacterial (2) viral (3) fungal infection (Bader , 2016 ) World Health Organization(2019) : Define as Meningococcal meningitisis . : is an acute form of bacterial meningitis caused by Neisseria Meningitis. Meningitis is an acute inflammation of the piamater and the arachnoid membrane surrounding the brain and spinal cord. Therefore, meningitis is always cerebrospinal infection. ( Basvanthapa, 2009) 5 Types of Meningitis 6 Most common bacteria causing meningitis: Meningitis is most common caused by a viral or bacterial infection Neisseria meningitidis (meningococcus) Haemophilus influenzae (haemophilus) Listeria monocytogenes) (listeria Streptococcus pneumonia Group B Streptococcus Escherichia coli 7 Extremes of age (< 5 or >60 years) Diabetes mellitus, chronic kidney failure, adrenal insufficiency, hypoparathyroidism, or cystic fibrosis. Compromised immune system like AIDS, alcoholism ,use of immunosuppressant drugs. Recent exposure to others with meningitis, with or without prophylaxis. Malignancy. Pregnancy. 8 Pathophysiology Causative organism enter the blood stream Cross the blood brain barrier Inflammatory reaction in meninges Inflammation of subarachnoid space and pia mater Inflammation may cause increase Icp CSF flows in subarachnoid space CSF cloudiness or infected CSF cell count increase and increase brain endues and in cranial pressure 9 Etiology and Epidemiology • There are many microorganisms that can cause meningitis including bacteria, viruses, fungi, parasites; also drugs may be a cause (e.g., NSAIDs, metronidazole, and IV immunoglobulin). 10 Bacteria that cause meningitis include : • Pachymeningitis. • Haemophilus influenzae meningitis. • Pneumococcal meningitis. • Streptococcus agalactiae meningitis • Meningococcal meningitis. • Listeria monocytogenes meningitis. • Gram-negative bacilli. • Staphylococcal meningitis: it colonized in the normal skin flora. S epidermidis is the most common cause of meningitis in patients with CNS shunt (ventriculoperitoneal). • Additional causes of meningitis: Congenital malformation of the stapedial footplate, Head and neck surgery, penetrating head injury, comminuted skull fracture, and osteomyelitic erosion, Skull fractures. 11 Characteristic clinical signs and symptoms can be absent Blood culture imaging spinal tab (lumber puncture) Blood cultures • Blood samples are placed in a special dish to see if it grows microorganisms, particularly bacteria • limitation : Pretreatment with antibiotics decreases the yield. 12 Spinal tap (Normally computed tomography, CT) scans of the head may show swelling or inflammation. May lead to a substantial delay in the initiation of antibiotic treatment, which leads to poor outcome. Spinal tap (lumbar puncture) This fluid is sent to the lab and analyzed to determine if there is an infection. “We determine:” WBC(leukocyte) count increase Protein concentration increase Glucose concentration decrease then we perform CSF culture and Gram stain Is the procedure of taking fluid from the spine (CSF) in the lower back through a hollow neddle. Kerning`s signs One of the physically demonstrable symptoms of meningitis is Kernig's sign. Severe stiffness of the hamstrings causes an inability to straighten the leg when the hip is flexed to 90 degrees. Brudzinski`s signs One of the physically demonstrable symptoms of meningitis is Brudzinski's 13 sign. Severe neck stiffness causes a patient's hips and knees to flex when the neck is flexed. The first symptoms are usually Fever , vomiting , headache and feeling unwell. Limb pain ,pale skin ,and cold hands and feet often appear earlier than the rash, neck stiffness , dislike of bright lights and confusion. Septicemia can occur with or without meningitis . Typical clinical features are 1. Headache 2. Nuchal rigidity 3. Photophobia 14 infants (<2years) older than 2 years Complications • Advanced bacterial meningitis may cause brain damage and death. 50% of patients may have a serious complications within a week, however in 30% of survivors long term sequlae are seen. • Complications include hearing loss, cortical blindness, other cranial nerve dysfunction, paralysis, muscular hypertonia, ataxia, multiple seizures, mental motor retardation, focal paralysis, subdural effusions, hydrocephalus and cerebral atrophy. 15 New Biomarker • The differentiation between acute bacterial and non bacterial meningitis is challenging because they share many similar clinical symptoms, such as fever and headache. • A new biomarker (Procalcitonin) has been studied for the diagnosis of bacterial meningitis. 16 Management Delay in treatment has been associated with a poorer outcome. First: we should start treatment with wide-spectrum antibiotics while confirmatory tests . After identification of the pathogen antibiotic therapy as appropriate for patient age and condition. Rapid transport to the emergency department (ED) because of the early severe complications. 17 Treatment Viral Meningitis Bacterial Meningitis Other Meningitis Antiviral Antibiotic Based on the underlying cause Plenty of Fluids Fluids Anti-Fungal in fungal infections Antipyretics Antipyretics Symptomatically treatment Pain killers Pain killers Antiemetic Antiemetic Cancer-related meningitis requires therapy for the specific cancer. Allergic reaction or autoimmune disease may be treated with corticosteroids. Corticosteroids Corticosteroids Anticonvulsant Bed Rest 18 Nursing Management ➢ Monitor Vital sign 4 hourly or when needed, check the level of consciousness. ➢ Maintain airway clear. ➢ Maintain Peripheral line. ➢ Administer prescribed medication timely immediately after sample collection. ➢ Care of unconscious pt (lung sounds, posture change, DVT prophylaxis etc) ➢ Maintain GCS, pupil reaction & size ➢ Monitor intake and output. ➢ Keep patient pain free. ➢ Prevent from hypoxia ➢ Mechanical ventilation, pco2 keep 30 -35mm ➢ Monitor ABG, S ➢ Infection control precaution. ➢ Give antipyretics ➢ Antihypertensive drugs and check for BP fall. ➢ Diuretics… assess for dehydration and electrolytes ➢ Anti convulsants ➢ Auscultate chest for over hydration and pneumonia ➢ Change posture, to Prevent from bed sore. ➢ Head side at 30 to 35 degree, keep head midline and do not flex head (prevent to inc ICP) ➢ Provide oral care to prevent from ulcer, assess skin integrity. ➢ Prevent patient from injury related to seizures or altered L 19 These steps can help prevent meningitis: 1. Wash your hands. 2. Practice good hygiene. 3. Stay healthy. 4. Cover your mouth. 5. If you're pregnant, take care with food. 20 Nursing Care Plan Assessment Nursing Planning Implementation Rational diagnosis Subjective data Pt verbalized Feeling Fatigue Weakness Loss of appetite Restless Pale Imbalance nutrition Less than body requirement related to inability to ingest and digest food and absorbed as evidence by loss of appetite Short term goal To maintain adequate fluid balance and nutrition in 8 hours Objective Data Long Term Goal B.P 90/60 Pulses 96b/min Respiration 22b/minutes Temperature 100F After 1 week Pt will be able to eating proper. Fever settled. To educate the family Assess general To monitor condition body weight for Monitor vital signs fluid and Identify risk for nutritional malnutrition status . Monitor pt`s weight. Dietry patterns Assess nutritional daily pattern,including are considered in planning Food meal. preference,caloric intake and diet history To maintain pleasant Provide comfortable environement. and delightful Reduce environment during unpleasant meal times. factors that add to appetite loss. Independent Dependent Maintain i/v line Administer multivitamin Vit .D as advised by doctor. Administer TPN as order by doctor Evaluti on Maintain adequate Nutrition and fluid balance. A high potassium diet maintain therapeutic, serum potassium level.. 21 Assesment Nursing Planning Implementation Rational Diagnosis Subjective Data Acute pain related to meningeal irritation Patient verbalized having pain from 3 to 4 days. Objective Data B.P 90/50 H/R 120 b/min Res 16 b/min Temp 100F Short Independent -Note for the location , Term scale, intensity and Planning onset of pain. After 4 hours of nursing interventions the patient will be able to display reduction of pain . Long Term Planning After 2 to 3 days of nursing intervention the patient will identify personal triggers to avoid having migraine attacks and successfully be headache free. -Maintain a calm and quite enviromement -Use relaxation technique such as: -Deep breathing exercise -Provide a dim light and good ventilation. -Offer back rubs massage, slow rhythmic breathing , repositioning and other diversional activity such as listening music . Dependent Administer pain medications as ordered. Evaluati on -To determine the nursing care to be given to the patient. After 4 hours of nursing interventions, goal met. Patient relieved of -To minimize pain and stimulus that there is no could non verbal aggravate the indicators of condition of pain.. the patient . -To promote comfort and relaxation. -Serve as non pharmacolog ical methods for reducing pain and promoting comfort. To help relieve of pain. 22 Assessment Diagnosis Planning Intervention Rational Evaluation Anxiety related to actual or perceived I am not feeling threat to health good since many to health as days evidenced by the increased tension. Short Independent -Different -Assess the level of term patient’s level of anxiety will planning: anxiety affect the Goal met After 4 hours of nursing interventions, the patient was relaxed was reduced.. Subjective data: Objective data: Restlessness Narrowed vision Voice quivering Hands tremors Facial flushing Sweating B.P 160/90 H/R 110 b/min Res 22 b/min After 10 to 30 minutes of nursing intervention the client will be able to know some techniques on how to lessen the anxiety such as deep breathing and exercise.. -Monitor vital signs -Acknowledge awareness of patient’s anxiety -Instruct patient to do deep breathing exercises. long term planning -Provide accurate information After series of about the situation nursing intervention the clients anxiety will be eliminated.. -Establish a therapeutic conversation. coping mechanism of the client -To identify physical responses linked to medical and emotional conditions , -This may help the client to relax. -Helps the client to identify what is reality based. -Using simple language -To avoid a contagious effect of anxiety. Dependent -The will help the client to trust you. Administer pain medications as ordered. 23 24 Summary Meningitis is an inflammation of the protective membrane lining the brain and spinal cord caused by most often by a viral or bacterial infection that crosses the body`s blood brain barrier. Meningitis is diagnosed by a lumber punctur, in which a small amount of fluid is collected from the spinal cord. There are two main types of Meningitis, Bacterial and viral. Bacterial meningitis is less common, but more serious. Bacterial Meningitis is treated with and antibiotics and the majority of patients make a full recovery. Viral Meningitis usually required no treatment beyond painkillers. Most patients make a full recovery from meningitis .A small number of infected people end with hearing or vision loss or brain damage. Reference 25 Basvathapa , BT.(2009). Medical surgical nursing. 2nd edition. New dheli (indial:japee brother. Medical publisher Linpincoh, (2004). Allied medicine . 12th edition .America.series edition . Brunner and Suddarth`s , (2016).A text book of medical surgical nursing (14th edition ). New Delhi. 26 27