Pathology
Code Range (80047- 89398) - 10 Questions
80047 - 80081Organ or Disease Oriented Panels
80305 - 83992Drug Assay Procedures
80145 - 80299Therapeutic Drug Assays
80400 - 80439Evocative/Suppression Testing Procedures
80500 - 80502Clinical Pathology Consultations
81000 - 81099Urinalysis Procedures
81105 - 81479Molecular Pathology Procedures
81410 - 81471Genomic Sequencing Procedures and Other Molecular Multianalyte Assays
81490 - 81599Multianalyte Assays with Algorithmic Analyses
82009 - 84999Chemistry Procedures
85002 - 85999Hematology and Coagulation Procedures
86000 - 86849Immunology Procedures
86850 - 86999Transfusion Medicine Procedures
87003 - 87999Microbiology Procedures
88000 - 88099Anatomic Pathology Procedures
88104 - 88199Cytopathology Procedures
88230 - 88299Cytogenetic Studies
88300 - 88399Surgical Pathology Procedures
88720 - 88749In Vivo (eg, Transcutaneous) Laboratory Procedures
89049 - 89240Other Pathology and Laboratory Procedures
89250 - 89398Reproductive Medicine Procedures
Panels FTR
1. All of the elements must match completely, If no match, code separately
2. Do not use mod “52” to reduce panel and mod “51” is not used to report multiple panels
3. Do not report two or more panel codes that include any of the same constituent tests
performed from the same patient collection.
4. If a group of tests overlaps two or more panels, report the panel that incorporates the greater
number of tests and report the remaining tests using individual test codes (eg, do not report
80047 in conjunction with 80053)
5. If any test(s) performs in addition to those specifically indicated for a particular panel, those
tests should be reported separately in addition to the panel code.
Note: Unbundling of panel codes are not allowed
DRUG ASSAY
(80305- 80307)
Presumptive/Screening/Preliminary:
•Identifies if the patient is using a drug or not i,e Presence or absence of a drug
•It is a Qualitative test
(80320-80377) Definitive/Confirmatory:
•Confirm the drug and also quantifies the amount of drug
•It may be Qualitative or Quantitative
(80150-80299) Therapeutic Drug Assays:
•Performed to monitor clinical response to a known, prescribed medication.
Note: Do not multiply the drug assay codes for multiple drug analytes tested.
Consultation Pathology :
88329 Pathology consultation during surgery
88331 Pathology consultation during surgery; first tissue block, with frozen section(s), single
specimen
88332 Pathology consultation during surgery; each additional tissue block with frozen section(s)
(List separately in addition to code for primary procedure)
88333 Pathology consultation during surgery; cytologic examination (eg, touch prep, squash
prep), initial site
88334 Pathology consultation during surgery; cytologic examination (eg, touch prep, squash
prep), each additional site (List separately in addition to code for primary procedure)
Note:
 For intra-operative consultation on a same specimen requiring both frozen section and
cytological evaluation, Use 88331 and 88334
 Do not report 88333 in conjunction with 88331 and also do not report (9924199245)or (99251-99255)
Examples:
During Surgery 1 tissue block and 1 cytology exam performed in pathology consultation:
88331, 88334
During Surgery 2 tissue blocks performed in pathology consultation: 88331, 88332
During Surgery 1 tissue block and 2 cytology exam performed in pathology consultation:
88331, 88334 X 2
Specimen 1 : 3 frozen sections on two tissue blocks and 2 Cytology exams : 88331, 88332,
88334 X2
Specimen 2: 3 tissue blocks with single cytology exam: 88331, 88332 X 2, 88334
Specimen3: 3 cytology exam for 3 different sites: 88333, 88334 X2
Urine Analysis:
Surgical Pathology:
1. Services 88300 through 88309 include accession , examination, and reporting.
2. They do not include the services designated in code 88311- 88365 and 88399, which
are coded separately
3. The unit of services for codes 88300 through 88309 is the specimen
4. Do not report 88302-88309 on the same specimen as part of Moh’s Surgery
Surgical Pathology FTR:
1. Report 88331- Intraoperative Frozen section exam or
88311- decalcification if performed
2. Identify if only Gross examination or both Gross and microscopic examination done.
a. 88300- Gross exam only
b. 88302-88309 - Gross and Microscopic exam
3. Identify the level as per the specimen tested
4. Code diagnosis using ICD- 10
5. Report modifier “26” if interpretation only . Do not use “TC” or “26” if global
component
Use of Modifier “91”
Do not use modifier “91” when the test is repeated
1. For confirmation without physician’s order to repeat it
2. Due to technician’s fault
3. And the repeat test is performed on the same specimen
Chemistry:
Look for the specimen tested and look for the Test performed
When an analyte is measured in multiple specimens from different sources, or in specimens that are
obtained at different times, the analyte is reported separately for each source and for each specimen.
82270 Blood, occult, by peroxidase activity leg, guaiac), qualitative; feces, consecutive collected
specimens with single determination, for colorectal neoplasm screening lie, patient was
provided 3 cards or single triple card for consecutive collection)
82271 other sources
82272 Blood, occult, by peroxidase activity leg, guaiac(, qualitative, feces, 1-3 simultaneous
determinations, performed for other than colorectal neoplasm screening {Blood urea nitrogen
[BUN], see 84520, 84525)
82274 Blood, occult, by fecal hemoglobin determination by immunoassay, qualitative, feces, 13 simultaneous determinations
Anatomic Pathology(88000-88099)- Necropsy/Autopsy
 Codes 88000-88016 Gross examination only
 Codes 88020-88029 Gross and Microscopic w/o CNS
 Code 88036-88037 Gross and Microscopic exam Limited
 Regional(88036)
 Single Organ(88037)
 Forensic
88040 Forensic Means Crime
88045 Coroner has to determine the cause of death
Reports physician services only
Chromosome Analysis
Chromosome analysis for Breakage syndrome:
88245 20-25 cells
88248 50-100 cells and 2 karyotypes
88249 100 cells and Clastogen stress( UV radiation ionizing radiation)
Chromosome analysis:
88261 5 cells, 1 karyotypes and banding tech
88262 15-20 cells, 2 karyotypes and banding tech
88263 45 cells, 2 karyotypes and banding tech
88264 20-25 cells
88280 Additional karyotypes
88283 Additional banding(NOR, C-banding)
88285 Additional cells
Reproductive Medicine
Practice Questions
1. A patient presents to the ED with chest pain, shortness of breath, and a history of
congestive heart failure. The physician performs a 12 lead EKG which indicates a
myocardial infarction without ST elevations. The physician immediately orders
myoglobin, quantitative troponin, and CK enzyme levels to be run once every hour for
three consecutive hours.
a. 83874-99, 83874-76, 83874-91, 84484-99, 84484-76, 84484-91, 82250-99,
82250-76, 82250-91
b. 83874, 83874-91 x2, 84484, 84484-91 x2, 82550, 82550-91 x2
c. 83874-91 x3, 84484-91 x3, 82250-91 x3
d. 83874 x3, 84484 x3, 82550 x3
2. The Mary came to the pathology clinic along with her husband for chromosome analysis,
because the previous pregnancy he had a spina bifida baby shown on the TIFFA scan and
terminated the pregnancy at that time , this time they came for chromosome analysis. The
pathologist done 15 cells, one karyotype, with banding Code the procedure.
A.
B.
C.
D.
88261, 88285
88262
88267
88261
3. Cryopreservation of embryo(s) and sperm
A.
B.
C.
D.
89258, 89259
89342, 89343
89346, 89259
89258, 89242
4. The correct code for reporting Blood count; hemogram and platelet count, automated, and
automated complete differential WBC count (CBC), describes an automated blood count of
five groups of white blood cells (eg, basophils, eosinophils, monocytes, lymphocyte and
neutrophils), along with hemogram and platelet count.
A.
B.
C.
D.
85025
85004, 85027
85027, 85032, 85041
85041, 85027
5. Three individual tissue specimens from a partial left breast mastectomy were submitted for
surgical pathology gross and microscopic evaluation. The reason for surgery was lesions in the
breast. Each specimen required an independent comprehensive examination, report, and
decalcification. Which code(s) should be reported for the laboratory services?
A. 88307 x 3, 88311
B. 88307, 88331, 88323 x 3
C. 88305
D. 88305, 88331, 88323 x 3
6. A physician performed an automated urinalysis with microscopy. The test revealed the
presence of bacteria. The urine specimen was then cultured, and a quantitative colony count
was obtained. How should you report the lab services?
a.
b.
c.
d.
81001, 87086
81000, 87086
81002, 87086
81001, 87088
7. A physician ordered a lab test to determine the amount of chloride present in two different
urine specimens for the same patient. The first specimen was obtained in the morning, and
the second specimen was obtained in the afternoon. How should you report these lab
services?
a.
b.
c.
d.
82438, 82436
82438, 82436
82436, 82436-91
82438, 82728
8. Arielle underwent a combined rapid anterior pituitary evaluation panel with multiple
exposure and suppressions and had acute hepatitis panel. How these tests should be
reported.
a.82024X4, 83002X4, 83001X4, 84146X4, 83003X4, 82533X4, 84443X4
b.80418, 80074
c.80418, 80076
d.80076
9.
Physician orders basic and comprehensive metabolic panels with calcium ionized. Select the
code(s) on how this is reported.
a. 80053, 80047
b. 80053
c. 80047, 82040, 82247, 82310, 84075, 84155, 84460, 84450
d. 80053, 82330
10. Dr.Ronald a pathologist, completed both gross and microscopic surgical pathology after lung
wedge biopsy. Dr.Myth, the surgeon, sent a single specimen to the laboratory after the
completion of limited biopsy by thoracotomy. How would Dr. Ronald report his service?
a. 88300, 88307
b.32151, 88305-26
c.88307
d.32098, 88307-26
11. A surgical specimen was removed from the proximal jejunum during a resection for
adenocarcinoma and was submitted to surgical pathology for gross and microscopic
examination. The correct code for this service is:
a.
b.
c.
d.
88307
88309
88304
88305
12. This patient presented to the laboratory yesterday for a creatine measurement. The results
came back at higher than normal levels; therefore, the patient was asked to return to the
laboratory today for a repeat creatine test before the nephrologist is consulted. Report the
second day of test only.
a.
b.
c.
d.
82540 ×2, R79.89
82550, R79.89
82550, R79.81
82540, R79.89
13. Physician performed drug class screening on the patient who presented to the clinic in an
unconscious state. Confirmatory test is performed to verify the presence of barbiturates and
Benzodiazopines using Immunoassay.
a.
b.
c.
d.
80305,80345,80346
80306
80307
80305×2
14. A 23 yrs old female with a history of schizophrenia and depression treated with prescription
medications, presented to ED in a coma. The treating physician orders a single drug class
screen for alcohol, barbiturates, benzodiazepines, phenothiazines and tricyclic
antidepressants and it was performed by using chemistry analyzer. Code the procedure(s).
a.80305x5
b. 80305
c. 80307
d.80307x5