Phoenix College Block III Common Med-Surg Pharmacology Memory Check List IV Push Medications *Make note of the trade/generic names of all medications Medication Therapeutic Class Actions/ Indications Side Effects Furosemide (IVP) Antihypertensio -Inhibit Na+ and n water reabsorption from the loop of Henle and distal renal tubule. So K+, Mg+, Ca2+ may also excreted. -Watch for K+ level Morphine (IVP) Opioid Lopressor (IVP) Antihypertensiv -Treatment of es HTN Beta-blocker -Block stimulation of B1-adrenergic receptors -Bradycardia 5mg -Depression -Congestive Heart Failure -Pulmonary edema Famotidine (IVP) -Histamine H2 receptor antagonists -Antiulcer agent -Hallucination -Arrhythmias -Nausea -Decrease electrolytes -Hypotension -Increase urinate -Dehydration -Ototoxicity -Treatment of -Respiratory moderate pain or depression severe pain -Binds to opiate receptors in the CNS. Alters the perception of an response to painful stimuli, while producing generalized CNS depression. -Treatment of ulcer and GERD -(IV)Prevention and treatment of upper GI bleed. -Inhibit the action of histamine at the H2-receptor site located primary in gastric parietal cells, resulting in Rate of Administration -PO -IV/IM 20mg q12hr, diluted and given over 2 mins inhibition of gastric acid secretion hydromorphone (IVP) Opioid -Treatment of -Respiratory moderate pain or depression severe pain -Binds to opiate receptors in the CNS. Alters the perception of an response to painful stimuli, while producing generalized CNS depression. 1.5 – 2 mg, q3-4hr Phenergan (IVP) Antihistamins, Phenothiazine antiemetics -Changing the actions of chemicals in your brain. Promethazine also acts as an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. - Treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. -Ringing in your ears -Dry mouth 25mg/min Narcan (IVP) Antidote for Opioid -Reversal of CNS depression and respiratory depression due to overdose -Competitively blocks the effects of opioids -HTN -Hypotension -Ventricular fibrillation 0.02-2mg q 2-3mins Metoclopramide (IVP) Antiemetic/gast ric stimulant -Prevention of emesis related to chemotherapy and surgery -Block dopamine receptors in the chemoreceptor trigger zone of CNS -Bone marrow suppression -Drowsiness 10-15mg 30 min before meals and at bedtime Insulin, regular (IVP) Antidiabetic agent Lower blood glucose by stimulating glucose uptake in skeletal muscle and fat -Hypoglycemia IV/0.1unit/kg/hr continuous infusions Insulin, regular (IVP) Antidiabetic agent Lower blood glucose by stimulating glucose uptake in skeletal muscle and fat -Hypoglycemia IV/0.1unit/kg/hr continuous infusions Zofran (IVP) Antiemetic -Prevent of N/V -Block the effects of serotonin at receptor sites -HA -Dizzy -Fatigue -Constipation -Diarrhea 0.15mg/kg Diphenhydramine (IVP) Antihistamines - Competes with histamine for H1receptor sites. -Seizure, 50mg/ml Thrombocytopenia , IV Piggyback Medications Medication Therapeutic Class Actions/ Indications Side Effects Cefazolin (IVPB) Antibiotics Inhibits cell-wall - anorexia synthesis, -Diarrhea promoting osmotic instability; usually bactericidal. Rate of Administration 2 g/10 mL in 0.9% NSS Ceftriaxone (IVPB) 3rd generation Anti-infective -Treatment of infections -Bind to the bacterial cell wall membrane, causing cell death -Seizure -Rash 1-2 g, q12-24hr Ciprofloxacin (IVPB) Antibiotics - Inhibits bacterial DNA synthesis, mainly by blocking DNA gyrase; bactericidal. -Seizure -HA -Restleness 200 mg/20 mL Cefepime (IVPB) 4th generation Anti-infective -Treatment of infections -Bind to the bacterial cell wall membrane, causing cell death -Seizure -Rash 1-2 g, q12-24hr Levofloxacin (IVPB) Antibiotics -Inhibits bacterial DNA gyrase and prevents DNA replication, transcription, repair, and recombination in susceptible bacteria -Dizziness -HA -Insomnia Infusion (premixed): 250 mg in 50 mL D5W Piperacillin/ Tazobactim (IVPB) Antibiotics -Treatment of infections -Bind to the bacterial cell wall membrane, causing cell death - Seizure, Pseudomembrano us colitis 3.375 g q 6hr Vancomycin (IVPB) Antibiotics Treatment of potentially lifethreatening infections when less toxic antiinfectives are contraindicated -Ototoxicity -Hypotension 500mg q 6hr Metronidazole (IVPB) Antiprotozoals Direct-acting -Seizure trichomonacide -HA and amebicide that works inside and outside the intestines 500 mg/100 mL Linezolid (IVPB) Antibiotics Prevents bacterial protein synthesis by interfering with DNA translation in the ribosomes -Headache -Dizziness -Insomnia 2 mg/mL Meropenum (IVPB) Antibiotics -Inhibits cell-wall synthesis in bacteria. Readily penetrates cell wall of most gram-positive and gram-negative bacteria to reach penicillin-binding protein targets. -Apnea -HA Powder for injection: 500 mg or 1 g Daptomycin (IVPB) Antibiotics Bactericidal; binds -Confusion to and depolarizes -Dizziness susceptible -Cardiac Failure bacterial membranes to inhibit protein, DNA, and RNA synthesis. Powder for IV infusion: 350-mg vial