8 Science 8 Quarter 4 – Lessons 1-3: Living Things and their Environment ILLUSTRATION: RICARDO B. RUIZ LAYOUT: ARVIN C. AUSTRIA Department of Education ● Republic of the Philippines Science 8 Alternative Delivery Mode Quarter 4 – Lessons 1-3: Living Things and Their Environment First Edition, 2020 Republic Act 8293, section 176 states that: No copyright shall subsist in any work of the Government of the Philippines. However, prior approval of the government agency or office wherein the work is created shall be necessary for exploitation of such work for profit. Such agency or office may, among other things, impose as a condition the payment of royalties. Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names, trademarks, etc.) included in this module are owned by their respective copyright holders. Every effort has been exerted to locate and seek permission to use these materials from their respective copyright owners. The publisher and authors do not represent nor claim ownership over them. Published by the Department of Education Secretary: Leonor Magtolis Briones Undersecretary: Diosdado M. San Antonio Development Team of the Module Writers: Orlie L. Orbita – Bagbaguin NHS Gretchen DS. Luares – Dalandanan NHS Sally R. Juanillas – Canumay West NHS Content Validators: Ma. Suzette S. Falcunitin – Dalandanan NHS Dr. Nimrod V. Dela Cruz – Canumay West NHS Language Validators: Liza Vinda P. Unay – Canumay West NHS Ma. Suzette S. Falcunitin – Dalandanan NHS Layout Artist: Aljhun L. Genova – Lawang Bato NHS Management Team: Dr. Meliton P. Zurbano, Assistant Schools Division Superintendent OIC-OSDS Mr. Filmore R. Caballero, Chief-Curriculum Implementation Division Mrs. Jean A. Tropel, Division EPS In-Charge of LRMS & ADM Coordinator Dr. Ma. Lea Q. Prondo, Division EPS in Science Printed in the Philippines by ________________________ Department of Education – National Capital Region Office Address: Pio Valenzuela Street, Marulas, Valenuzuela City, 1440 Telefax: (02) 292 – 32 – 47 E-mail Address: sdovalenzuela2015@gmail.com 2 Lesson Digestive System 1 Living things need energy to do work. The energy which the animals and humans need comes from food. Food fuels the body cells with the energy they need to operate. But the food that living thing takes in is a complex material and it must be broken down into smaller pieces which the body can absorb and utilize. In this lesson, you will be able to learn how the parts of the digestive system work harmoniously in a healthy individual and discover how each organ is structurally designed to perform its function. This will also give you a clearer understanding on how intricate the processes are which cannot be duplicated even by the most advanced technology. What I Know Directions: Choose the letter of the correct answer. Write your answers before each number. 1. Digestion takes place in a long tube-like canal called alimentary canal, or the digestive tract. Food travels through these organs in the following order. a. mouth – esophagus – stomach – small intestine – large intestine - rectum b. mouth – esophagus – stomach – large intestine – small intestine – rectum c. mouth – stomach – esophagus – small intestine – large intestine – rectum d. mouth – stomach – gullet – small intestine – large intestine – rectum 2. What structures in the small intestine absorb the nutrients that result from the digestive process? a. villi b. duodenum c. intestinal glands d. intestinal muscles 3. What happens when food reaches the stomach? a. Nothing. No digestion occurs in the stomach b. The food moves quickly into the small intestine c. Juices mix with the food and stomach muscles squeeze it d. The food is completely digested and is absorbed by tiny blood vessels in the walls of stomach 4. How do you call to the movement of the digestion products, electrolytes, vitamins and water across the gastrointestinal tract epithelium and into the underlying blood and lymphatic vessels? a. ingestion b. absorption c. digestion d. secretion 5. The following are preventive measures to avoid digestive problems EXCEPT ________. a. drinking plenty of water c. consuming high calorie fast food b. avoiding excessive intake of alcohol d. eating food rich in fibers 3 What’s In Food plays a major role in the survival of species. Food gives organism energy that enables them to carry out many activities they do each day by day. Organisms are able to obtain energy from the foods they eat through the process of digestion. Digestion is the process of breaking down foods into smaller nutrients. These nutrients are circulated to the different parts of the body through the bloodstream and assimilated by the cells What’s New If you’re an ice cream lover, then just the sight of this yummy ice cream cone may make your mouth water. The “water” in your mouth is actually saliva, a fluid released by glands that are part of the digestive system. Saliva contains digestive enzymes, among other substances important for digestion. When your mouth waters at the sight of a tasty treat, it’s a sign that your digestive system is preparing to digest food. Figure 1.1. Ice cream Source:https://hips.hearstapps.com What is It The food you eat takes an incredible journey through your body -- from top (your mouth) to bottom (your anus). Along the way the beneficial parts of your food are absorbed, giving you energy and nutrients. The digestive system is used for breaking down food into nutrients which then pass into the circulatory system and are taken to where they are needed in the body. It consists primarily of the alimentary canal (digestive tract) and accessory organs. Figure 1.2. shows where food is digested in man. The parts are enumerated in Table 1 together with the organs that assists in digestion. The food tube of man is about nine (9) meters long. Table 1: Parts of the Digestive System and their Functions Alimentary Canal (Digestive Tract) Mouth Esophagus Stomach Small intestine Large intestine Rectum Anus Accessory Organs Liver Gall bladder Pancreas Function mechanically breaks down the food by your teeth muscular tube through which food passes from the mouth into stomach big muscular pouch where digestion begins absorption of food particles takes place here known as colon which absorbs water, secretes mucus and eliminates undigested materials stores the feces opening where the feces is eliminated Function secretes bile, a greenish fluid that emulsifies fats and neutralizes the stomach acid and increase the efficiency of digestion and absorption where bile is stored secretes digestive enzymes that breakdown proteins, carbohydrates, and fats 4 Digestion starts when food is taken into the mouth. As you chew, you are breaking the food into small pieces as a means of mechanical digestion. The pieces mix with saliva which is, a watery liquid made by the salivary glands. It softens and wets the food in the mouth and also initially starts chemical digestion through the enzymes present in it. Enzymes are molecules that speed up chemical reactions. Enzymes in saliva known as salivary amylase or ptyalin helps breakdown food starches or carbohydrates into maltose, a double sugar. Maltase, another type of enzyme will breakdown maltose into glucose, a simple sugar. Then the food passes through the esophagus. Muscle contractions in the esophagus help move the food down to the stomach. This wavelike contraction of the food tube is called peristalsis. Figure 1.2. Digestive System Source:https://www.niddk.nih.gov The stomach is made up of muscles that churn and help mix the food with gastric juices and acids and break it into even smaller pieces. Other enzymes such as lipase and protease help breakdown proteins in the stomach and fats in the small intestine, respectively. Digested molecules of food are absorbed through the small intestine. The walls of the small intestine contain many folds that are lined up with tiny fingerlike protrusions called villi and microvilli. During absorption, these nutrients pass through the walls of the intestine and into the bloodstream where they get transported to the different parts of the body. Secretions of the liver and pancreas also enter the small intestine, playing an important role in digestive process. The pancreas secretes variety of digestive enzymes that breakdown carbohydrates into simple sugars, proteins into amino acids and fats into fatty acids. Moreover, it also makes insulin, chief hormone in your body for metabolizing sugar. Figure 1.3. Liver, Gall Bladder and Pancreas Source: https://img.webmd.com/ Because digestive enzymes cannot act efficiently on large fat globules, the liver secretes bile – a greenish fluid that emulsifies fat globules into smaller droplets. These small droplets are easily digested by digestive enzymes. The gallbladder is a green muscular sac attached to the liver where bile is stored. The undigested parts of food or those that were not absorbed by the body passes through the large intestine and stores the feces at the rectum until they are eliminated in the opening known as anus. This process is called elimination or defecation 5 Digestive Processes Your digestive system is uniquely constructed to do its job of turning your food into the nutrients and energy you need to survive. And when it’s done with that, it handily packages your solid waste, or stool, for disposal when you have a bowel movement. Here are the different activities include in the digestive processes: 1. Ingestion – process where food is taken in through the mouth and broken down by teeth and saliva. Figure 1.4. Digestive Processes 2. Digestion – breaking down of food into small pieces. Source:https://bodell.mtchs.org/ a. Mechanical Digestion – physical breakdown of large pieces of food into smaller pieces. b. Chemical Digestion – carried out by the enzymes that speeds up the chemical reaction. 3. Absorption – process by which food molecules move into the blood stream to be carried to the cells of the body. 4. Assimilation – incorporation of food molecules into the cells of the body to be used as energy, structural materials or storage products. 5. Egestion – process of eliminating undigested food from the body What’s More Activity 1: Matchy Matchy! Objective: Identify the key parts of the digestive system Materials: Worksheet Pen Directions: Match the name of each organ with the letter that represents on the diagram below. ______ 1. Stomach _____8. Small intestine ______ 2. Gall bladder _____9. Pharynx ______ 3. Oral cavity _____10. Anus ______ 4. Liver _____11. Pancreas ______ 5. Large intestine ____ 12. Esophagus ______ 6. Rectum ____ 13. Tongue ______ 7. Salivary glands Figure 1.5. Digestive System Activity 2: Trace my Path! Objective: Trace the pathway of food through the digestive tract Materials: Worksheet Pen 6 Directions: Complete the paragraph below: In humans, the process of digestion begins in the _____________ where food is chewed into small pieces by the teeth. Once the food is swallowed, it passes through the ____________ and into ____________. Once in the stomach, the food is ___________. After spending some time in the stomach, the food is sent into the ____________ where nutrients are ___________. The ___________helps by producing some digestive juices called bile. The undigested food goes into the _______________. The rectum stores the __________ and eliminated through the process of defecation by the _________. Activity 3: Arrange and Explain! Objective: Arrange and explain the different digestive processes in the body. Materials: Worksheet Pen Directions: Arrange the following processes in order of which they occur and give a brief sentence to explain each one Digestive Description Processes 1. 2. 3. 4. 5. What I Have Learned 1. Explain the difference between mechanical and chemical digestion. _____________________________________ 2. How does digestive system break down food to nourish the body? ______________________________________ What I Can Do I Can Do it! Create a paper doll of the digestive system using the given template. Draw the different organs of the digestive system and label them. Assessment A. Multiple Choice. Choose and write the letter of the best answer before each number. 1. Which of the following is NOT an organ of the digestive tract? a. mouth b. stomach c. liver d. esophagus 7 2. What is the primary function of small intestine? a. vitamin conversion c. absorption of nutrients b. mineral secretion d. waste secretion 3. Which of the ff. accessory organs acts as a temporary storage site for bile. a. gall bladder b. pancreas c. liver d. intestine 4. Which of the following organs is NOT correctly matched with its respective function? a. pharynx – passage of air & food c. small intestine – absorption b. stomach – defecation d. mouth – ingestion 5. The digestive system processes food into usable and unusable materials are sent to the body’s cells as food. What happens to unusable materials? It goes ___. a. into the pancreas to await disposal b. to the right ventricle to await disposal c. into the large intestine to await disposal d. to the small intestine to await disposal B. Match Column A to Column B by writing the letter of the correct answer before each number. COLUMN A COLUMN B 1. Breakdown of large, insoluble food molecules into small a. Egestion water-soluble molecules using mechanical and chemical b. Digestion processes. c. Assimilatio 2. Movement of digested food molecules into the cells where n they are used. d. Absorption 3. Intake of substances into the body through the mouth. e. Ingestion 4. Passing out of undigested food as feces through your anus 5. Movement of digested food molecules across the walls of intestines into the blood or lymph. Lesson 2 Cellular Reproduction You have learned that every organism possesses a unique characteristic and one of these characteristics is reproduction. The cellular level of reproduction, in the form of cell division, provides the backdrop for the organism level of reproduction. In this lesson, you will be able to determine the stages of cellular reproduction and explain how cells grow and divide to form new cells. 8 What I Know Directions: Choose the letter of the correct answer. Write your answers before each number. 1. Which of the following best describes the cell cycle? a. Cells growth and development takes place during interphase while its reproduction takes place during mitotic phase. b. Cells growth and development takes place during mitotic phase while its reproduction takes place during interphase c. The nucleus of a cell divides during interphase while the cytoplasm of the cell divides during mitotic phase. d. The nucleus of a cell divides during mitotic phase while the cytoplasm of the cell divides during interphase. 2. Which of the following shows the correct sequence of the cell cycle? a. S - G1- G2- mitosis- cytokinesis c. Cytokinesis- mitosis- G1 - S- G2 b. G1-S - G2- mitosis – cytokines d. Mitosis -G1 - S- G2 - cytokinesis 3. Which of the following is not a function of mitosis? a. Development (baby in mother’s womb) b. Repair of damaged cells in multicellular organisms c. Production of gametes d. Asexual reproduction in unicellular organisms 4. What is the correct order of the stages of mitosis? 1- METAPHASE 2 - TELOPHASE 3- ANAPHASE 4 - PROPHASE a. 4,1,2,3 b. 2,3,1,4 c. 4,1,3,2 d. 1,2,3,4 5. What is the key difference between spermatogenesis and oogenesis? a. Spermatogenesis is the formation of 4 sperm while oogenesis is the formation of one egg cell. b. Spermatogenesis is the formation of 2 sperm while oogenesis is the formation of one egg. c. Spermatogenesis results in only 1 sperm; oogenesis results in 2 eggs. d. Spermatogenesis results in only 1 sperm; oogenesis results in 4 eggs. What’s In Every second of an hour in your daily lives, there is an important event going on in your body and that is - cells are dividing. When a cell divides, it will make new cells. We call this process “cell division” and “cell reproduction”. A dividing cell undergoes series of growth and development stages between its “birth” (formation by the division of a mother cell) and reproduction (division to make new daughter cells) which is also known as the Cell Cycle. Figure 2.1 Source: https://www.twinkl.ae/illustration/ 9 What’s New Does it made you think, when you find some cut on any part of your body and a few days later, it’s gone and healed? When you look at the mirror and you notice that you grow a lot bigger than you were when you were six years old and got looks from both of your parents? You don’t even think anything other than the amazing process that cause it to happen. All of these things happened because of cell division. The cut in your arm that was healed after a few days and increase in your height happened because of division and production of new cell called Mitosis. And having looks from both of your parents is caused by another type of cell division called Meiosis. Mitosis and Meiosis are part of the Cell Cycle. What is It Cell cycle is composed of interphase and cell division phase. The bulk of the cell cycle is spent in the “living phase”, known as interphase. Interphase is further broken down into 3 distinct phases: G1 (Gap 1), S (Synthesis) and G2 (Gap 2). G1 phase - cell increases in size, cellular contents duplicated S phase - DNA Replication or DNA Synthesis, each of the 46 chromosomes is replicated by the cell G2 phase - cell grows more and organelles develop in preparation for cell division Cell Division Alternating with the interphase is the cell division phase. In eukaryotic cells, there are two types of cell division: mitosis and meiosis. Mitosis is a type of cell division that produces two identical cells with the same number of chromosomes. Mitosis is divided into four phases. Prophase - The nuclear membrane and nucleoli still present. The chromosomes are thicker and shorter because of repeated coiling. Figure 2.2. Mitosis At this stage, each chromosome is Source: https://image.shutterstock.com/image-illustration/animal-cellmitosis-illustration-chromosomes-260nw-1539718535.jpg made up of two identical sister chromatids attached at one point, called the centromere. Spindle fibers are formed Metaphase - The nuclear membrane has disappeared while the coiled chromosomes align at the metaphase plate. Spindle fibers are attached to a protein called kinetochore at the centromere of each sister chromatid of the chromosome. Anaphase - The paired centromeres of each chromosomes separate toward the opposite poles of the cells as they are pulled by both spindle fibers through their 10 kinetochores. This liberates the sister chromatids. Each sister chromatid is now a single chromosome. Telophase - The chromosomes are at the opposite poles and start to uncoil. The nucleoli and nuclear membrane reappear while the spindle fibers disappear. There is also cytokinesis (division of the cytoplasm) to form two separate daughter cells immediately after mitosis. Meiosis reduces the chromosomes number in half. Cell undergoes two rounds of cell division (Meiosis I and Meiosis II) to form four daughter cells, each with half the chromosome number as the original parent cell and with a unique set of genetic material as a result of crossing over (a segment of a sister chromatid of one chromosome is exchanged with the same segment of the chromatid of the homologous chromosome) Meiosis I •Prophase I - Meiosis starts with this stage •Metaphase I - Homologous chromosomes align at the equatorial plate •Anaphase I - The homologous chromosomes separate from each other and start their movement toward the opposite poles. •Telophase I - Two nuclei are produced, each containing only half the chromosome number of the original parent cell. Meiosis II is similar to mitosis. It consists of the following stages: prophase II, metaphase II anaphase II and telophase II. Each doublestranded chromosome attaches to a spindle fiber then its centromere splits into two and the two strands of the chromosome move to opposite poles. At the end of the cell division, four haploid daughter cells are produced. Figure 2.3 Gametogenesis in animals Surce:https://www.jing.fm/iclipt/ibJhbii/ Gametogenesis The production of an egg cell and a sperm https://www.vcbio.science.ru.nl/en cells is called gametogenesis. Gametogenesis involves meiosis to produce haploid /imagegametes in preparation for sexual reproduction. gallery/show/labels/PL0286/ Spermatogenesis is the production of sperm cells in testes of male animals. Meiosis produces four small cells of similar size. These cells become spermatozoa or sperms. Egg cells are produced in the ovary of female animals through the process of oogenesis. When a cell in the ovary undergoes meiosis I, two cells -one big and one small (polar body)- are produced. Meiosis in gametogenesis may not always proceed normally. In humans, accidents like failure of the chromosomes to separate during meiosis I may cause abnormal conditions. 11 What’s More Activity 1: Cell Cycle Objective: Describe the stages of the cell cycle. Materials: Worksheet, Pen, coloring materials Directions: On the given diagram, lightly color the G1 phase BLUE, the S phase YELLOW, the G2 phase RED, and the stages of mitosis ORANGE. Color the arrows indicating all of the interphases in GREEN. Color the part of the arrow indicating mitosis PURPLE and the part of the arrow indicating cytokinesis YELLOW. Source: https://www.pinterest.ph/pin/426645764684730019/ Guide Questions: Use the diagram to answer the following questions: 1. What is the longest stage of the cell cycle? _________________________________________________________________________________ 2. In what stage does the G1, S and G2 phases happen? __________________________________________________________________________________ 3. In what phase of the cell cycle does cell division occur? __________________________________________________________________________________ 4. In which phase of the cell cycle does the cell grows? __________________________________________________________________________________ 5. During what phase of the cell cycle is DNA replicated? __________________________________________________________________________________ 6. During what phase of the cell cycle does the cell prepares for Mitosis? __________________________________________________________________________________ 7. What are the stages of Mitosis? __________________________________________________________________________________ Activity 2: ACROSS THE STAGES! Objective: Identify the changes in each stage of mitosis and meiosis Materials: Worksheet Pen 12 Part A. Below are the illustrations of the stages of Mitosis. Determine the events in each stage by looking at each illustration. Put a check on all descriptions of the events in each stage. PROPHASE METAPHASE ANAPHASE __1. The chromatin condenses into sister chromatids __2. Nuclear membrane starts to disappear __3. Centrioles start to form spindle fibers __4. Chromosomes separate __1. The sister chromatids disappear. __2. Spindle fibers are attached to the centromere of sister chromatids. __3. Centrioles start to form spindle fibers. __4. Sister chromatids line up along the equatorial plate. __1. Sister chromatids separate into chromosomes. __2. Sister chromatids are pulled toward opposite poles. __3. Shortening of spindle fibers. __4. Formation of cleavage furrow. TELOPHASE __1. Reappearance of nucleolus and nuclear membrane __2. Chromosomes condenses __3. Spindle fibers disappear __4. Cleavage furrow deepens that divides the cell __5. Chromosomes start to uncoil. Guide Questions: 1. At the end of telophase, cytokinesis occurs. What do you think will happen to the cell? _____________________________________________________________________________ 2. How many daughter cells will be produced in Mitosis? __________________________________________________________________________________ 3. How will you compare the chromosome number of each daughter cell and the parent cell? ______________________________________________________________________ Part B. DOUBLE MATCHING TYPE: Match Column A to its correct illustration in Column B and its corresponding description in Column C. Write your answer in the space provided. A to B A to C A I. Prophase I II. Metaphase I III. Anaphase I IV. Telophase I V. Prophase II B 1 2 3 4 5 C Chromosomes gather at the poles. Cytoplasm divides A The nuclear envelope breaks down, genetic material is exchanged through crossing over B Pairs of homologous chromosomes line up at the equator C Chromatids remain attached at their centromeres as the spindle fibers move the homologous chromosomes to opposite poles A new spindle forms around the chromosomes. D E 13 6 VI. Metaphase II 7 VII. Anaphase II VIII. Telophase II 8 Chromosomes line up at the equator F A nuclear envelope forms around each set of chromosomes, the spindle breaks down and cytoplasm divides, resulting in four haploid cells. Centromeres divides enabling the chromatids now called chromosomes to move to opposite poles of the cell. G H Part C. Complete the Venn diagram to compare mitosis and meiosis. Use the phrases on each box by writing its corresponding number inside the diagram. Mitosis BOTH Meiosis 1.Crossingover 2. Synapsis 3. Formation of spindle fibers 4. Produces haploid cells 5. For formation of egg cells and sperm cells 9. Cytokinesis and Karyokinesis take place 6.Formation of two daughter cells 10. Produces four daughter cells 7. Occurs in plant and animal cells 8. Involves cellular division 11.Produces cells identical to parent cells 12.For growth and repair of damaged body cells Activity 3: Spermatogenesis vs. Oogenesis Objective: Differentiate spermatogenesis from oogenesis Materials: Worksheet Pen Word Bank Directions: Complete the graphic organizer below by writing the correct statement on each box. Choose your answer inside the Word Bank. Point of Comparison Location Number of gametes produced Products of meiosis When does the process begins When does the process stops If cytokinesis during meiosis is equal Spermatogenesis Oogenesis - ovary - seminiferous tubules in testes - one per month -millions per day - cytoplasm split unequal - equal division of cytoplasm - 1 egg cell, 3 polar bodies - 4 cells - puberty - during development of fetus - at menopause -until death 14 What I Have Learned Directions: Read the paragraph and fill in the missing words. Choose the correct words from the box below. Cells reproduce in a process called (A______________), which split into two main parts. The first part is called (B.____________) where cell absorbs nutrients and grows in size. During this time, it also copies its (C_____). Once the cell is big enough, it begins the second part called (D.____________) All of these steps together are called the (E.__________. (F.________) the process of cell division that usually forms the male sperm in animals and female (G. ______). It occurs in two successive divisions. One diploid cell (2n) in the male or female reproductive organs (testes and ovaries) produces (H._______) haploid daughter cells. These cells become the (I._____) sperm cells in males, or one egg cell and (J_______) polar bodies in females. (K._______) is the process that produces cells with the chromosome number (L._____) as the parent cell. Usually one diploid cell produces (M._____) new ‘daughter ‘cells. It produces all human body cells except the gametes. (N._____), (O._____), (P._____) and (Q._____) are the 4 phases in both meiosis and mitosis Interphase DNA cell division cell cycle Mitosis four two three Metaphase Prophase ovum (egg) Anaphase Meiosis Prophase same Telophase What I Can Do Directions: Answer the following questions. 1. Why is cell division important in the life of an organism? ___________________________________________________________________________________________ 2. How does cell division helps our body stay healthy? ___________________________________________________________________________ 3. Why is meiosis vital to sexually reproducing organisms? ___________________________________________________________________________ Assessment Multiple Choice. Choose and write the letter of the best answer before each number. 1. What is the correct sequence in which the stages of mitosis occur?? a. Metaphase-anaphase-prophase-telophase. b. Prophase-metaphase-anaphase-telophase c. Telophase-anaphase-metaphase-prophase d. Anaphase-telophase-prophase-metaphase 15 2. Which terms are mismatched? a. Interphase: DNA replication b. Prophase I -synapsis c. Cytokinesis-cell plate formation d. Metaphase- centromere division 3. What type of cell division results in daughter cells having an exact copy of chromosomes from parent cell? a. Mitosis b. Meiosis c. Interphase d. Synapsis 4. Which of the following phase sister chromatids move towards opposite poles? a. Prophase b. Metaphase c. Anaphase d. Telophase 5. Which of the following is not a function of mitosis? a. Growth c. Replacement of dead cells b. Recovering from injuries d. Formation of sex cells 6. Which of the following describes the number of daughter cells produced in mitosis and meiosis? a. 4 haploid daughter cells in mitosis and 2 diploid daughter cells in meiosis b. 4 diploid daughter cells in mitosis and 2 haploid daughter cells in meiosis c. 2 diploid daughter cells in mitosis and 4 haploid daughter cells in meiosis d. 2 haploid daughter cells in mitosis and 4 diploid daughter cells in meiosis 7. What happens during crossing over? a. chromosomes collide b. chromosomes exchange genetic material c. chromosomes die d. chromosomes replicate 8. Which of the following happens during gametogenesis? a. Mitosis b. Meiosis c. Mitosis and Meiosis d. Synapsis 9. In what stage of Meiosis I does crossing over occurs? a. Leptotene b. Zygotene c Pachytene d. Diplotene 10. Which of the following is the purpose of meiosis in gametogenesis? a. growth of spermatogonium and oogonium b. maturation of oogonium and spermatogonium c. replicate DNA in the cell d. reduces the number of chromosomes in resulting daughter cells 16 Lesson Mendelian Pattern of Inheritance 3 Reproduction process is an anchor to the variation of an organism. The importance of blending the traits contributed by both parents for the succession of a specie. Understanding how we can predict and make control of traits not to be inherited but needs quality development for mankind. In this lesson, you will be able to describe Mendel’s principle of inheritance, identify expressed traits and predicting probability transfer of traits from parents to offspring by using Reginald Punnett diagram. We cannot deny that yielding a good variety of offspring specially our natural resources such as plant and animals can make a general change in all aspects of our life, health, environment and society What I Know Choose the letter of the correct answer. Write your answers on a separate sheet of paper. 1. Which of the following express a phenotype of an offspring? a. An infant having XY gametes. c. A dwarf fruit bearing mango tree. b. A kitten of XX gametes. d. A puppy of XXY allele. 2. A green (pod color) is crossed with another green (pod color) phenotype. What possible ratio of an offspring it will produce? a. ¾ yellow, ¼ green c. 100 % green b. ½ yellow, ½ green d. 100 % yellow 3. Male black dog was cross breed to a female white fur dog. The pair produces 4 black fur puppies and 2 white. What can you say about it? a. White fur of female dog is the dominant trait. a. Black fur of male dog is the dominant trait. b. Black fur of male dog is a recessive trait. c. White and black fur are equally dominant. 4. Which describes an allele expresses in TT, Rr, rr, XY, XX? a. Genotype b. Hybridization c. Phenotype 5. d. Mutation In a cross between heterozygous round (Rr) and wrinkled (rr). What is the phenotypic ratio of the offspring? a. 3:1 c. 4:0 b. 1:1 d. 2:1 X R r r Rr rr r Rr rr 17 What’s In You have just learned that the human body is composed of different kinds of cells which made up your tissues and organs, with special function that help build you as a new Individual. Reproduction is the biological process by which new individual organisms- “offspring”- are produced from their “parents”. It happens when there is a union of male (Father) and female (Mother) reproductive cells known as gametes. Gametes are the sex cells known as sperm and egg cell of your parents that each carries chromosome where genes or traits embed. As you have previously learned, Homologous Chromosomes during meiosis, undergoes crossing over of genes causes synapse that allows shared DNA sequence. Have you ever wondered, why you do not exactly look alike with neither your father, mother nor your siblings? What’s New BUILD ME UP! Directions: Arrange the scrambled letters to reveal the word best describe by the following statements. Write your answer on the space provided. (GROGER LEMEND) a monk scientist known as “Father of Genetics” who designed the “Pea experiment”. __ __ __ __ __ __ __ __ __ __ __ __ 2. (ODIMNTAN) a trait more expressed of offspring from their parents. __ __ __ __ __ __ __ ___. 3. (GEEN) a factor of traits or unit of inheritance. ___ ___ ___ ___ 4. (AGMESET) refer to sex cells- the egg and sperm. __ __ __ __ __ __ __ 5. (CREESSVIE) a trait which did not appear in F1 generation. __ __ __ __ __ __ __ __ __ 6. (LALESEL) pair of factors or genes which controls the appearance of a particular trait. __ __ __ __ __ __ __ 7. (HEPNOTYEP) refers to the appearance or external expression of traits such as dwarf, tall, short, round, curly. __ __ __ __ __ __ __ __ __ 8. (NEGNOPEYT) refers to the particular alleles such as TT, bb or Rr. __ __ __ __ __ __ ___ __ 9. (EHREDTIY) is the transmission of traits from one generation to the next. __ __ __ __ __ __ __ __ 10. (EGNETCIS) a science of heredity and variation. __ __ __ __ __ __ __ __ 1. 18 What is It Genetics is a branch of science that deals with the study of heredity and variation. Gregor Johann Mendel (1822-1884), An Austrian monk, is known as the “Father of Genetics”. After 8 years statistically experimenting garden peas, he was able to publish a paper in 1866 on the mechanism of Heredity or transmission of traits from one generation to the next. Why Pea plant? Garden pea is considered a good material because its stamen and pistil are enclosed by petals protecting the stigma from stray pollen, with pair of contrasting traits, easy to cultivate, short generation time and thus, ensure cross and self-pollination. The table below shows the characteristics of garden pea plant studied by Gregor Mendel. Figure 3.1. Gregor Mendel Figure 3.3 Figure 3.2: Characteristics of Garden Pea Plant Source: https://qph.fs.quoracdn.net/main-qimg ff8d4ffe93e2d18da91e98586b713d4b Mendel studied how traits are being passed from one generation to the next. Mendel first produced pure-breeding plants. He allowed his pea plant to self -pollinate for many generations until all the offspring had the same features as the parents, generation after generation. Pure -breeding peas make up the parental or P1 generation. Mendel began cross pollinating of parental (P1) generation peas with contrasting traits. For example: Pea plant (P1) of round seed x Pea plant (P1) of wrinkled seed = all the offspring had round seeds. These offspring of parental cross are called the first Filial (F1) generation. First filial (F1) generation are also called hybrid, resulted from a cross between two pure-breeding plants with contrasting traits. When the plants from the F1 generation were crossed with each other or selfpollinated the offspring (F2) Second filial generation were of two types. 19 External traits expressed such as round, wrinkled seed shape is considered the Phenotype (physical characteristics). The most distinct physical trait is a dominant trait. For example, round and wrinkled seed shape produces round seed shape offspring. On the other hand, Genotype refers to letter or a variable (T, t, R, r) demonstrating an allele of paired factor or genes with contrasting trait. Factor or gene serves as the unit of inheritance. A characteristic not visible in an offspring is a masked trait known as recessive trait. Dominant genes are demonstrated by a big letter, for example green seed coat is expressed in pair of letter GG mean for being dominant, while yellow seed coat presented in pair of small gg to show being recessive. Expression of genes with similar letters neither big or small (TT, tt) tells the trait is homozygous while a combination of big and small (Tt) indicates a heterozygous. THE MENDELIAN LAWS OF HEREDITY The Law of Independent Assortment - The appearance of a particular trait in each organism is controlled by pairs of gene or factors The Law of Dominance – the dominant trait prevents the expression of the recessive trait The Law of Segregation - the pair of genes segregate or separate from each other during gamete formation. Monohybrid Cross using Punnett Square Punnett Square is a simple diagram named after Reginald Punnett which will help you visualize the results of a cross. Using this device, the symbols for all the possible alleles carried by male gametes are arranged on the top portion whereas the female gametes are located on the left side. By combining the alleles of both male and female gametes, all possible gametes combination of the offspring can now be determined. Figure 3.4: Monohybrid Cross using Punnett Square Source:vhttps://www.thoughtco.com What’s More Activity 1: Oh My! It’s a Genre. Objective: Describe the Mendelian Principle of Inheritance in a Pea plant Experimentation. Materials: Worksheet Pen 20 Directions: Write numbers 1 to 5 on the space provided before each box to show the sequence of the Pea Plant experimentation, then answer the guide questions accurately. Transferred pollen from stamens of white flower to carpel of purple flower Examined all purple flower offspring. Pollinated carpel matured into pod Removed stamens from purple flower Plant seeds from pod Guide Questions: 1. What characteristic of the pea plant was transferred? __________________________________________________________________________ 2. How do you call that process of transferring of pollen from stamen to carpel of a flower? ______________________________________________________________ 3. What is the resulting color of the offspring? __________________________________________________________________________ 4. Does the pea plant offspring get its resulting color from its pea plant parent? __________________________________________________________________________ 5. Do you think there will be a chance for a white pea plant flower to exist? Why? _____________________________________________________________________ Activity 2: Twinning to be True …… Objective: Predict phenotypic and genotypic expressions of traits following simple patterns of inheritance Materials: Worksheet Pen Part A. Procedure: 1. Analyze the given trait transferred from parent to offspring of Mendel’s Pea plant experimentation Monohybrid Test Cross Mendel crosses height of a pure breed tall pea plant with a dwarf pea plant. What do you think will be the inherited factor and characteristic of the offspring? Will it be all tall or dwarf? Use the Punnett Square below and answer the following questions. Father Phenotype: Tall Mother Phenotype: dwarf Genotype: TT Genotype: tt 21 Monohybrid Cross a. b. c. d. e. List down the genotypes of offspring. List down the phenotypes of offspring Write its genotypic ratio. Write its phenotypic ratio. Percentage of tall offspring? dwarf offspring? 2. Cross pollinate F1 (First Filial generation) to another F1 (Filial generation) to produce F2 Second Filial generation Monohybrid Cross f. g. h. i. j. List down the genotypes of offspring. List down the phenotypes of offspring Write its genotypic ratio. Write its phenotypic ratio. Percentage of tall offspring? dwarf offspring? Part B. Guide Questions: 1. What is the expressed characteristic of F1 offspring? in F2? _________________________________________________________________________________ 2. When F1 generation cross pollinated to another F1 generation, how many trait /s is /are observed to all offspring? What are these traits? __________________________________________________________________________________ 3. How do you call this trait or characteristic that expressed the greatest number of offspring? _______________________________________________________________________ 4. How about the least expressed trait of an offspring? __________________________________________________________________________________ 5. When did dwarf recessive trait express? __________________________________________________________________________________ What I Have Learned 1. How did Johan Gregor Mendel trace the traits transferred of Parent pea plant to offspring? ____________________________________________________________________________ 2. Describe the Three Mendelian Principle of Inheritance. ____________________________________________________________________________ 3. What is the difference between Phenotypic and Genotypic ratio? _____________________________________________________________________________________________ 22 What I Can Do Mirror, Mirror! 1. Make a Photo Scrapbook presentation of your Family Map generation from your grandparents, parent, siblings and siblings Family (if have their own) 2. List down all observable traits in your family. Use a table chart to present it. 3. Put a heart if traits are manifested either from your mother or father. 1. 2. 3. 4. CHARACTER/TRAITS COMPLEXION (Fair/Dark) COLOR OF THE EYES EAR LOBES (Attached /Free) HAIR TYPE (Curly/ Straight) Guide Questions: 1. 2. 3. 4. 5. What are the traits manifested from your family? Which of these traits you have inherited from your mother, father or both? What do you mean by inherit? How are these traits passed on from parents to offspring? How many percent of the traits were expressed from your grandparent to your siblings? How about from your father or mother? Calculate the phenotypic and genotypic ratio expressed in your family. Assessment A. Multiple Choice. Choose and write the letter of the best answer before each number. 1. Which of the following is an example of Mendellian Law of Dominance? a. The short trunk of palm tree. c. Heterozygous tall palm tree. b. Homozygous tall palm tree. d. Dominant tall palm tree. 2. Which phenotypic ratio will be expressed if a green (pod color) plant is crossed with another of the same phenotype? a. ¾ yellow, ¼ green c. 100% green b. ½ yellow, ½ green d. 100% yellow 3. In a cross between heterozygous round and wrinkled, what is the phenotypic ratio of the offspring? a. 3:1 b. 1:1 c. 4:0 d. 1:3 23 4. If in a cross, a pure yellow seeded pea plant is crossed with a pure greenseeded plant, all F1 generation are yellow. What conclusion can you make? a. yellow seed is the dominant trait. b. green seed is the dominant trait c. yellow and green are equally dominant d. neither yellow nor green combined. B. Draw a smiling emoji if the describe trait is a dominant trait and sad emoji if it is a recessive trait ____1. BB black mice ______3. cc curly hair ______5. FF fair skin color ____2. ww white cat ______4. LL long eyelashes ______6. CC straight hair C. Monohybrid Cross Problem. 1. In mice, black fur (B) is dominant over white (b). Cross a homozygous dominant mouse with a white mouse. What are the possible phenotypes and genotypes in the offspring? Write the genotypic and phenotypic ratio. Draw a Punnett square 2. In summer squash, white fruit color (W) is dominant over yellow fruit color (w). If a squash plant homozygous for white is crossed with a plant homozygous for yellow, what will the phenotypic and genotypic ratios of the offspring. Draw a Punnett square. Additional Activities To learn more about Cross with Two factors (dihybrid) and Inferring genotypes of Blood types you can watch video lesson entitled Dihybrid Genetic Cross https://www.youtube.com/watch?v=1QU2phs-hws 24