CASEANALYSIS REPORT 24(103), May - June, 2020 ARTICLE Medical Science ISSN 2321–7359 EISSN 2321–7367 Regaining activities of daily living in patient with middle cerebral artery stroke- A case report Simran Mishra, Palak Darda, Waqar M. Naqvi, Arti Sahu Ravi Nair Physiotherapy College, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India Authors contact information Simran A. Mishra - mishrasimran2998@gmail.com; ORCID ID- https://orcid.org/0000-0002-0221-9423 Palak P. Darda - dardapalak@gmail.com; Orcid ID- https://orcid.org/0000-0003-1617-3486 Waqar M. Naqvi - waqar.naqvi@dmimsu.edu.in; Orcid ID - https://orcid.org/0000-0003-4484-8225 Corresponding author Professor and Head of Department, Community Health Physiotherapy, Ravi Nair Physiotherapy College, Wardha, Maharashtra, India; Email: waqar.naqvi@dmimsu.edu.in Article History Received: 11 March 2020 Reviewed: 13/March/2020 to 19/April/2020 Accepted: 20 April 2020 E-publication: 28 April 2020 P-Publication: May - June 2020 Citation Simran Mishra, Palak Darda, Waqar M. Naqvi, Arti Sahu. Regaining activities of daily living in patient with middle cerebral artery stroke- A case report. Medical Science, 2020, 24(103), 1731-1737 Publication License This work is licensed under a Creative Commons Attribution 4.0 International License. General Note Introduction: The World Health Organization (WHO) described stroke as: 'Rapidly developing clinical signs of focal (or global) cerebral disruption, with symptoms lasting 24 hours or longer or leading to death, with no obvious cause other than vascular origin. Physiotherapy has been found to be effective and rehabilitation is started as early as possible to minimize the patient potential to © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS Page ABSTRACT 1731 Article is recommended to print as color digital version in recycled paper. CASE REPORT ARTICLE functional recovery. Patient main concerns were inability to perform any activities including activities of daily living and inability use right upper and lower extremity for any task also major complaint was communication. Main clinical findings were decreased range of motion, minimal spasticity, and dependency of patient on others. Diagnosis Middle Cerebral Artery stroke was confirmed in MRI brain. Shoulder subluxation was confirmed on x-ray. Therapeutic interventions are found to be effective to minimise the complications and improve outcomes of patient. Physiotherapy intervention included Range of motion exercises (ROM), strengthening exercise, Functional mobility exercises, trunk control exercises, weight shift exercise, weight bearing exercises and use of electrical modalities. Motor assessment scales, Stroke Rehabilitation Assessment of Movement, Functional independent measure scale were major outcome measure for the patient. Conclusion: The patient was able to achieve certain goals like able to communicate through gestures, complete decline of spasticity, able to perform exercises and able to stand unsupported and improve functional capacity after continuous 12 week intensive physiotherapy rehabilitation program. Keywords: Middle Cerebral Artery, Stroke, Rehabilitation. 1. INTRODUCTION The World Health Organization (WHO) described stroke as: 'Rapidly developing clinical signs of focal (or global) cerebral disruption, with symptoms lasting 24 hours or longer or leading to death, with no obvious cause other than vascular origin (Truelsen et al., 2006). It is evident that in India, stroke is the foremost cause of death and disability (Pandian and Sudhan, 2013). The goals of physiotherapy rehabilitation include maintaining the range of motion (ROM) and preventing deformity. Furthermore, it is important to create awareness, promote active movement, improve trunk control and postural balance, improve functional mobility, initiate self care activities and improve overall functioning of patient (Susan, 2014). In this case, the patient initially denied to perform the investigations for the purpose of diagnosis of stroke and within a span of few days, he suffered from stroke, which was medically managed in an academic hospital. He was then referred by his physician to the physiotherapy department for rehabilitation. 2. PATIENT INFORMATION A 56 year old, right hand dominant, male hospital attendant visited the physiotherapy OPD on wheelchair with his son presenting with the complaints of inability to perform any activity from right side of his body (both extremities and trunk). He experienced difficulty in performing ADLs, inability to talk, and inability to stand and walk post-stroke due to weakness. Patient suffered from CVE (left hemiplegia) on 27-09-2019, wherein he had a headache which was sudden in onset, difficulty in talking and fall resulting from loss of consciousness. He was immediately admitted in hospital by his son. MRI brain and colour Doppler of left upper-extremity were done along with other blood investigations. On 28-09-2019, Intra-arterial Thrombolysis was done. For the next 15 days, patient was on Inj. Mannitol, Inj. Strocit Phes IV, antiplatelets and anticoagulants. Patient also had a past history of Transient Ischemic attack (TIA) 3 years back. 3. CLINICAL FINDINGS On admission in physiotherapy OPD (Day 1), after taking proper informed consent complete evaluation was done. Initial examination of mental status couldn’t be performed due to patient’s difficulty in communication. There was difficulty in comprehension and impairment in receptive language. Sensory examination was also limited, being secondary to communication inability. Motor Assessment: Complete evaluation of spasticity, joint play and soft tissue compliance was done. Motor assessment scale was utilised for assessment of motor function. Spasticity assessment: By utilising Modified Ashworth scale, spasticity was assessed. Spasticity in shoulder flexors, elbow flexors, wrist flexors and hip flexors were grade 1 and in knee flexors and ankle Plantarflexors, the grade was 1+. For extensor group of muscles, spasticity was 0. assistive device. Functional assessment: Patient required maximum assistance in basic ADLs (eating, bathing, transferring and toileting) as well as Instrumental ADLs (communication, transportation, and handling medication), as assessed using FIM. Clinical Photograph- On 1st day of assessment patient was wearing shoulder sling for subluxation (Figure 1). © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS Page Gait: Patient was unable to stand and walk. Prior to stroke, his gait level was functional in home and outdoor without the use of any 1732 Reflex: All deep tendon reflexes were normal i.e. 2+. ARTICLE CASE REPORT Figure 1 Patient on 1st day of assessment. Timeline Date of previous episode (TIA) 10-12-2015 Annual Health Check-up (further Investigation advised) 24-09-2019 Date of CVE (left hemiplegia) 27-09-2019 Date of operation (Intra-arterial Thrombolysis) 28-09-2019 Physiotherapy OPD admission 15-10-2019 Diagnostic Methods For the diagnosis of problems associated with patient’s day to day life including the activities of daily living and motor function, Motor Assessment Scale was used. Basic mobility activities were assessed using STREAM, FIM, which further helped to design the rehabilitation program and achieve the functional goals. Motor assessment scale - On Motor assessment scale patient total score was 8 on 1st day. FIM - On FIM scale patient total score was 18 on 1st day. STREAM – on this scale patient scored minimal points on 1st day. Diagnostic challenges Patient’s lack of education of the condition and ignorance led to altered prognosis. Patient’s denial for the check-up and tests led to stroke. Major challenge was communication with the patient, which was due to comprehension problem. Later, the patient started responding through gestures. Shoulder subluxation was also a challenge as it delayed the recovery. Therapeutic intervention Patient was managed through a multidisciplinary approach, which included a team of doctors, nurses, physiotherapist, speech therapist and occupational therapist to achieve good prognosis. Patient underwent physiotherapy session for the duration of 12 weeks, 6 days a week. Physiotherapy interventions were planned on the basis of functional goals, primary aim being prevention of Description Week 1 Patient was discharged from the hospital and was referred to physical therapy out-patient department for rehabilitation. His family member was educated about the condition and was explained about complete rehabilitation program based on patient condition. In © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS Page 1733 further complication and improvement of quality of life of the patient. ARTICLE CASE REPORT the first week of rehabilitation, patient positioning was taught, passive movements on the affected side with all precaution due to subluxation of shoulder was undertaken and active movements on sound side were incorporated. Exercise for normal limb included ROM exercise with 10 repetitions twice a day. In the later half of first week of rehabilitation patient was asked to perform combined ROM exercises for both extremities with the help of sound extremity. Stretching was integrated to reduce spasticity. Week 2-4 In second week of rehabilitation, Progressive resisted exercises were administered for normal limb after the subluxation resolved and the patient was promoted to use affected limb for activities. For reducing spasticity Roods approach was incorporated using Icing technique and stretching. Static orthosis was advised. Patient was taught segmental rolling. For strengthening upper extremity, Electrical muscle stimulation was given to the patient with following parameters- Stimulus pulse: Symmetric Biphasic, Amplitude: 060mA, Pulse width: 300µsec, Frequency: 25 to 50 Hz, Duty cycle: 10 sec off 10 sec on. In later half of 3rd week functional electrical stimulation was used for shoulder subluxation, wherein 2 electrodes were placed: one over supraspinatus and one over posterior deltoid. The frequency used for stimulation was set to 36 Hz in order to obtain tetanized muscle contraction. The intensity of FES was adjusted such that humerus elevation together with some abduction and flexion was produced to withdraw the head of humerus into the glenoid cavity. The ratio of contraction and relaxation was gradually changed from 10/2s to 30/2s for the FES sessions. It was applied for 5 days a week for 8 consecutive weeks depending on degree of subluxation. Week 5-8 In this phase of rehabilitation, spasticity was at maximum. Minimal active contraction of affected extremity was observed; hence repetitions of ROM exercise were increased. Exercises like knee to chest, straight leg raising, hip abduction, and adduction were incorporated in supine lying position. PNF was incorporated for both extremities. EMS and FES were continued. In sitting position, dexterity activities were continued. Since patient’s hand functions were poor, so activities like holding a glass, pen, etc were initiated. Functional task oriented activities were progressed. Week 9-12 In this phase of rehabilitation, spasticity grade was 1 on MAS. Mass movements were observed in both upper and lower limbs. Strength training was continued and functional task oriented exercises were promoted. Functional reach activities in sitting and standing were challenged in multi-direction approach .Transfers from bed to chair was progressed. Transitions of movement were advanced. Mirror therapy was useful in treating the patient as he was able to correct abnormal pattern. In all these phase of rehabilitation speech therapy was continued with regular physician follow ups. Follow up and outcomes Patient was assessed on day 1, at 4th week, 8th week and 12th week of intervention. Spasticity – Spasticity changes were grade 1 on day 1, grade 1+ & 2 in the 4th week, 1 in 8th week and 0 in 12th week. Reflex- Reflexes were 2+ on day 1, 3+ in 4th week, 2+ & 3+ (TA & Knee jerk) in 8th week and 2+ in 12th week. Motor Assessment Scale- Scores were 8, 14, 20 and 27 in respective weeks. Page 1734 FIM score- Scores were 18, 31, 41 and 47 in respective weeks. Figure 2 Shoulder subluxation resolved, Synergy pattern was also reduced. © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS CASE REPORT ARTICLE STREAM Initially patient was scored the least in performing voluntary movements of limb and basic mobility, which progressed to gross independence in various domains after 12 weeks of rehabilitation. Clinical Photographs of patient progression in Figure 2, 3, 4 and 5 during 2nd, 6th, 10th and 12th week of assessment respectively. Figure 3 Spasticity was reduced and Patient was able to raise affected hand and used it for picking objects. Sitting unsupported achieved. Page 1735 Figure 4 Patient was able to stand with walker unsupported. Figure 5 Patient performing reaches out activity in standing. © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS CASE REPORT ARTICLE Limitation Patient denial for checkup landed him with deadly disease. Shoulder subluxation following stroke was also challenging. Different types of stroke present with different impairments. Here patient’s dominant hemisphere was involved that lead to communication problem that became biggest challenge during treatment. This treatment protocol is specific and varies among patients with different outcome measures. 4. DISCUSSION In this case patient visited physiotherapy department with complains of inability to perform any activities using the right side of body including right upper limb and right lower limb, difficulty in performing ADLs, inability to talk, and inability to stand and walk due to weakness after stroke. Multiple treatment approaches were planned, such as Roods approach icing (cryotherapy) over spastic muscle, which was found to clinically diminish resistance of spastic muscle to rapid stretching and decrease or inhibit Clonus (Monaghan et al., 2017). Electrical muscle stimulation was used for strengthening or activating the weak muscle and enhanced the motor re-learning process following damage to central nervous system (Popović et al., 2009). Functional electrical stimulation was found effective in managing shoulder subluxation, wherein FES was applied on the Supraspinatus and Posterior Deltoid muscles along with giving conventional treatment. This was found to be more beneficial than conventional treatment alone (Koyuncu et al., 2010). Conventional therapy involves exercise regimen which include active exercises, resisted exercises and stretching. It plays as a key element of rehab that prevents atrophy of muscles. Stretching is integrated to preserve or increasing joint mobility by influencing the soft tissue extensibility of the joints (Wu et al., 2006). Proprioceptive neuromuscular facilitation exercises are very successful and were provided in the first week of stroke to generate voluntary control and improve everyday functional activities. The intervention should be started first from scapula to boost arm function. Because of the irradiation effect, tone and power are generated and improved at the upper extremity (Chaturvedi Poonam et al., 2016). Strength training was given for the sound extremities and later along with ROM exercise progressively resisted exercise were initiated for hemiplegic limbs. It is evident that strength training enhances the upper limb’s strength and function without causing an increase in tone or pain in people with strokes (Harris and Eng, 2010). 5. CONCLUSION This article is not much frequently publishing model regards “regaining activities of patients with middle cerebral artery stroke”. This case report demonstrated that the patient achieved maximum goal. This case report provided a comprehensive weekly rehabilitation protocol for a patient to gain basic ADLs. Outcome measures were markedly improved with regular exercise and rehab protocol. List of Abbreviations WHO- World Health Organisation ROM- Range of motion OPD- Out-Patient Department ADLs- Activities of Daily living CVE- Cerebrovascular Event TIA- Transient Ischaemic Attack MAS- Modified Ashworth Scale FIM- Functional Independent Measure Scale STREAM- Stroke Rehabilitation Assessment of Movement Author’s contribution All author made best contribution for the concept, assessment and evaluation, data acquisition and analysis and interpretation of 1736 the data. Funding: Page This research received no external funding. Conflicts of Interest: The authors declare no conflict of interest. © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS ARTICLE CASE REPORT Patient consent Proper consent was taken from patient for writing case report. REFERENCE 1. Chaturvedi Poonam, Singh Ajai K, Kulshreshtha Dinkar, Maurya Pradeep K, Thacker Anup K. Abstract 102: Effects of Proprioceptive Neuromuscular Facilitation Exercises on Upper Extremity Function in the Patients With Acute Stroke. 2016;1;9(suppl_2):A102–A102. 2. Harris JE, Eng JJ. Strength training improves upper-limb function in individuals with stroke: a meta-analysis. 2010;41(1):136–40. 3. Koyuncu E, Nakipoğlu-Yüzer GF, Doğan A, Özgirgin N. The effectiveness of functional electrical stimulation for the treatment of shoulder subluxation and shoulder pain in hemiplegic patients: A randomized controlled trial. 2010;32(7):560–6. 4. Monaghan K, Horgan F, Blake C, Cornall C, Hickey PP, Lyons BE, et al. Physical treatment interventions for managing spasticity after stroke 2017(2). 5. Pandian J, Sudhan P. Stroke Epidemiology and Stroke Care Services in India. 2013 1;15:128–34. 6. Popović DB, Sinkjær T, Popović MB. Electrical stimulation as a means for achieving recovery of function in stroke patients. 2009; 10;25(1):45–58. 7. Susan B O'Sullivan. Rehabilitation, 6th Chapter 17 Stroke’ Physcical edition; Philladelphia; F.A. Davis Company; 2014;645-678. 8. Truelsen T, Begg S, Mathers C. The global burden of cerebrovascular disease. 2006:67. 9. Wu C-L, Huang M-H, Lee C-L, Liu C-W, Lin L-J, Chen C-H. Effect on spasticity after performance of dynamic-repeatedpassive ankle joint motion exercise in chronic stroke Page 1737 patients. 2006;22(12):610–7. © 2020 Discovery Publication. All Rights Reserved. www.discoveryjournals.org OPEN ACCESS