Electrolyte Disorders: Signs & Symptoms Electrolyte Deficit [HYPO] Excess [HYPER] Sodium (Na+) 135-145 mEq/L (mmol/L) Hyponatremia [SEIZURE PRECAUTIONS] ↓ CNS function: irritability, apprehension, confusion, personality ∆s, tremors, tremors, seizures, coma, dry mucosa CV ∆s: postural HoTN; ↓CVP; ↓JV filling; ↑HR; thread pulse; cold clammy skin Hypernatremia [SEIZURE PRECAUTIONS] Intense thirst, Dry swollen tongue, sticky mucosa ↓ CNS function: restless, agitiation, seizures, twitching, coma CV ∆s: postural HoTN Potassium (K+) 3.5 – 5.0 mEq/L (mmol/L) Hypokalemia [CARDIAC MONITOR] Fatigue, muscle weakness, leg cramps, N/V, polyuria, hyperglycemia; paralytic ileus, soft flabby muscles ECG changes: ↓HR; ST depression, flat T wave; weak irregular pulse; Ventricular arrhythmias (PVCs, VTach, VFib) CNS ∆s: ↓reflexes, paresthesias Hyperkalemia [CARDIAC MONITOR] Diarrhea, ABD cramping, hypoglycemia ECG ∆s: VFib or standstill, irregular pulse; cardiac arrest (if sudden & severe); tall peaked T waves, prolonged PR, loss of P wave, widened QRS CNS ∆s: Irritability, anxiety, lower extremity weakness, paresthesias, irregular pulse Magnesium (Mg2+) 1.8-3.0 mEq/L (mmol/L) Hypomagnesemia CNS ∆s: ↑reflexes, tetany, neuromuscular irritability • Hallmark sign of chronic alcoholism • Resembles Hypocalcemia Hypermagnesemia ↓ CNS function: lethargy, drowsiness, somnolence ↓ Neuromuscular function: ↓reflexes, N/V, cannot walk • Respiratory & cardiac arrest Calcium (Ca2+) 8.8-10.5 mg/dL Hypocalcemia [AIRWAY PROTECTION] Fatigue, depression, anxiety CNS ∆s: Tetany, Chvostek/Trousseau signs, twitching, confusion, numbness, tingling (lips, fingers & toes), ↑reflexes, cramps, laryngeal spasm, seizures ECG ∆s: lengthened ST, prolonged QT, VTach Hypercalcemia Thirst, bone pain/fractures, polyuria, dehydration, nephrolithiasis; ↑ Interstitial (tissue) fluid ↓ CNS function: lethargy, weakness, ↓reflexes, ↓memory, confusion, personality ∆s, psychosis, stupor/coma, anorexia, N/V ECG ∆s: ↓ST, ↓QT; Ventricular dysrhythmias, ↑Digoxin effect Phosphate (PO4-) 2.5-5.0 mg/dL Hypophosphatemia ↓ CNS function: confusion, coma, muscle weakness (respiratory weakness, difficulty weaning from a mechanical ventilator); renal tubular wasting of Mg, Ca, HCO3, Cardiac issues (dysrhythmias, SV); osteomalecia, rhabdomyolysis Hyperphosphatemia Creates hypocalemia: muscle problems; tetany CaPO4 precipitates in the skin, soft tissue, cornea, vicera, and blood vessels 1