ESTABLISHMENT OF CONTROL DATA FOR LABORATORY ANIMALS RABBIT/ NEWZEALAND WHITE July- 2022 FACILITY NAME AND ADDRESS KCC BIO LABS Animal House Facility Survey No. 8/1, Tondagere Village, Tavarekere Post, Hebburu Hobli Tumakuru Taluk and District – 572 122 Tel: +91-7760847774 E-mail: kccbiolabs@gmail.com Page 1 of 7 CONTENTS Sl No. Particulars Page No. 1 Table 1: Summary of Gross Pathology 3 2 Table 2: Summary of Clinical Chemistry Data 4 3 Table 3: Summary of Hematology Data 5 4 Table 4: Summary of Bacteriological examination 6 5 Table 4: Summary of virological examination 7 Page 2 of 7 SUMMARY OF HEALTH MONITORING PARAMETERS: RABBIT/NEWZEALANDWHITE SUMMARY OF GROSS PATHOLOGY TABLE – 01 Strain Sex Gross Pathology M NAD F NAD NEWZEALANDWHITE Note: n=10, M- Male, F- Female; NAD – No abnormality detected, Organs examined liver, adrenals, kidneys, spleen, heart, ovaries / testes, stomach and ileum brain, thymus, Page 3 of 7 TABLE – 02 SUMMARY OF CLINICAL CHEMISTRY SPECIES/STRAIN - RABBIT/NZW Sl. no Parameters Males Rang e Females Rang e 1 Total Protein (g/dl) 4.78 to 7.33 4.9 to 8.9 2 Albumin (g/dl) 3.15 to 4.89 2.89 to 4.9 3 Glucose (mg/dl) 111.9 to114.9 92.9 to 116.9 4 ALT/SGPT (IU/L) 35.97 to 69.0 39.0 to 74.9 5 AST/SGOT (IU/L) 44.48 to 109 42.98 to 109 6 ALP (IU/L) 44.76 to 116.9 47.74 to 118.4 7 Total Cholesterol (mg/dl) 71.07 to 118.9 83.04 to123.9 8 Creatinine (mg/dl) 0.59 to 1.37 0.17 to 1.29 9 BUN (mg/dl) 19.09 to 25.4 14.99 to 23.38 10 TRI (mg/dl) 70.29 to 118.9 83.04 to 123.9 Note: n=10 ALT/SGPT Alanine transaminase / Serum Glutamic-Pyruvic Transaminase; AST/SGOT - Aspartate Transaminase / Serum Glutamic Oxaloacetic Transaminase; ALP – Alkaline phosphatase; BUN- Blood Urea Nitrogen; TRI–Tri glycerides; Page 4 of 7 TABLE – 03 SUMMARY OF HEMATOLOGY DATA SPECIES/STRAIN - RABBIT/NZW Sl. no Parameters Males Females Rang e Rang e 1 Total Leucocyte Count (WBC) (103 cells/µl) 8.8 to 12.9 8.5 to 13.0 2 Total Erythrocyte count (RBC) (106 cells/µl) 5.4 to 8.80 4.60 to 7.9 3 Hemoglobin (Hb) (g/dl) 10.8 to14.9 9.5 to12.2 4 Hematocrit (HCT) (%) 34.9 to 43.8 32.5 to 46.9 5 MCV (fL) 55.1 to 66.5 53.94 to 67.5 6 MCH (pg) 18.45 to 22.6 17.06to 22.56 7 8 MCHC (g/dl) Platelet Count (PLT) (103 cells/µl) 30.89 to 34.9 26.9 to 34.9 258 to 889 264 to 905 Note: n=10; obtained values are in mean; MCV – Mean Corpuscular Volume; MCH – Mean Corpuscular Hemoglobin; MCHC - Mean Corpuscular Hemoglobin Concentration Page 5 of 7 SUMMARY OF HEALTH MONITORING PARAMETERS: RABBIT/NEWZEALAND WHITE TABLE – 4 SUMMARY OF BACTERIOLOGICAL EXAMINATION Strain Sex Results M Negative F Negative NEWZEALANDWHITE (n=10) M- Male, F- Female Test Results Recent results Pathogen Test method Positive tested Results Pastuerella Morphological /biochemical tests Morphological /biochemical tests Staphylococcus Morphological /biochemical tests 0/10 Negative Streptococci beta hemolytica Morphological /biochemical tests 0/10 Negative Helicobacter spp. 0/10 Negative 0/10 Negative Page 6 of 7 SUMMARY OF HEALTH MONITORING PARAMETERS: RABBIT/NEWZEALAND WHITE TABLE – 5 SUMMARY OF VIROLOGICAL EXAMINATION Strain Sex Results M Negative F Negative NEWZEALANDWHITE (n=10) M- Male, F- Female Test Results Recent results Pathogen Test method Positive tested Results Rabbit Hemorrhagic Disease virus PCR 0/10 Negative Pastuerella multocida PCR 0/10 Negative Encephalitozoon cuniculi PCR 0/10 Negative Page 7 of 7