Mitosis Worksheet
11. A student is examining an onion root tip cell under a microscope. Based on her observations, the student
proposes that the onion root tip cell has completed interphase and is now in the first phase of mitosis. Which
of the following pieces of evidence would best support the student’s claim?
a. Separated sister chromatids are being pulled towards opposite ends of the cell.
b. The cell’s chromosomes are aligned across the metaphase plate.
c. Discrete chromosomes are scattered throughout the cell’s nucleus.
d. The cell’s DNA is dispersed within the nucleus as chromatin.
12. The following graph shows how cellular DNA content changes over the course of a typical mitotic cell cycle in
rapidly proliferating human cells. Based on the graph, which of the following labeled phases corresponds to S
phase of the cell cycle?
a. Phase A, because it is the longest phase of the cell cycle.
b. Phase B, because the amount of cellular DNA is doubled during this phase.
c. Phase C, because it occurs immediately after the amount of cellular DNA is doubled.
d. Phase D, because the amount of cellular DNA is halved during this phase.
13. A partial hepatectomy, or the surgical removal of a section of the liver, is often performed to treat tumors or other
abnormal growths in the liver. Following a partial hepatectomy, resting liver cells re-enter the cell cycle, duplicating
until the excised portion of the liver has been regenerated. According to the information above, performing a partial
hepatectomy causes liver cells to
a. Exit mitosis and enter G1 phase.
b. Exit G0 phase and enter G1 phase
c. Exit meiosis and enter G1 phase.
d. Exit G1 phase and enter G0 phase
14. The image below depicts a somatic cell nucleus before DNA replication. If the cell undergoes mitosis, which of
the following correctly depicts the daughter nuclei that would result?
Fill in the blanks.
1. A cell with 10 chromosomes undergoes mitosis. How many daughter cells are created? __ Each
daughter cell has ___ chromosomes.
2. The structure that is responsible for pulling the chromosomes apart during mitosis is called _____
3. After three rounds of mitosis, _____new cells will be created from one parent cell.
In the space provided, write the letter of the phase during which each event occurs.
a. Interphase
b. Metaphase
c. Prophase
d. Anaphase
e. Telophase
f. Cytokinesis
1.________The nuclear membrane begins to disappear.
2. ________Chromatids separate at the beginning of this phase.
3. ________The chromosomes move toward the center of the cell.
4. ________The cell grows rapidly.
5. ________Separate spindle fibers become attached to the centromeres of each chromosome.
6. ________DNA is duplicated.
7. ________A cell plate completely divides a plant cell.
8.________The nuclear membrane reforms.
The diagram below shows six cells in various phases of the cell cycle. Note the cells are not arranged in the
order in which mitosis occurs and one of the phases of mitosis occurs twice. Use the diagram to answer
questions below.
1. Cells A and D show an early and a late stage of the same phase of mitosis. What phase is it?
2. Which cell is in metaphase?
3. Which cell is in the first phase of mitosis?
4. In cell A, what structure is labeled X?
5. Place the diagrams in order from first to last.
6. What is the longest phase of the entire cell cycle?