Nervous System Functions 1. Receiving sensory input 2. Integrating information 3. Controlling muscles and glands 4. Maintaining homeostasis Neurons receive stimuli, conduct action potentials, and transmit signals to other neurons or effector organs. Glial cells Main Divisions of Nervous System supportive cells of the CNS and PNS, meaning these cells do not conduct action potentials. Instead, glial cells carry out different functions that enhance neuron function and maintain normal conditions within nervous tissue. Central nervous system (CNS). Neurons 5. Establishing and maintaining mental activity • brain and spinal cord Peripheral nervous system (PNS). • All the nervous tissue outside the CNS Sensory division. Conducts action potentials from sensory receptors to the CNS Motor division. Conducts action potentials to effector organs, such as muscles and glands A neuron (nerve cell) has a: Cell body – which contains a single nucleus Dendrite – which is a cytoplasmic extension from the cell body, that usually receives information from other neurons and transmits the information to the cell body Axon – which is a single long cell process that leaves the cell body at the axon hillock and conducts sensory signals to the CNS and motor signals away from the CNS Structural Types of Neurons Somatic nervous system. Transmits action potentials from the CNS to skeletal muscles. Autonomic nervous system. Transmits action potentials from the CNS to cardiac muscle, smooth muscle, and glands Enteric nervous system. A special nervous system found only in the digestive tract. Cells of the Nervous System Multipolar neurons have many dendrites and a single axon. Most of the neurons within the CNS and nearly all motor neurons are multipolar. Bipolar neurons have two processes: one dendrite and one axon. Bipolar neurons are located in some sensory organs, such as in the retina of the eye and in the nasal cavity. Pseudo-unipolar neurons have a single process extending from the cell body, which divides into two processes as short distance from the cell body. One process extends to the periphery, and the other extends to the CNS. The two extensions function as a single axon with small, dendrite-like sensory receptors at the periphery. Gray matter consists of groups of neuron cell bodies and their dendrites, where there is very little myelin. Glial Cells White matter consists of bundles of parallel axons with their myelin sheaths, which are whitish in color. Glial cells are the supportive cells of the CNS and PNS. Astrocytes serve as the major supporting cells in the CNS. Astrocytes can stimulate or inhibit the signaling activity of nearby neurons and form the bloodbrain barrier. Ependymal cells line the cavities in the brain that contains cerebrospinal fluid. Microglial cells act in an immune function in the CNS by removing bacteria and cell debris. Oligodendrocytes provide myelin to axons of neurons in the CNS. Schwann cells provide myelin to axons of neurons in the PNS. Myelin Sheath Myelin sheaths are specialized layers that wrap around the axons of some neurons, those neurons are termed, myelinated. Gaps in the myelin sheath, called nodes of Ranvier, occur about every millimeter Unmyelinated Neurons Unmyelinated axons lack the myelin sheaths. These axons rest in indentations of the oligodendrocytes in the CNS and the Schwann cells in the PNS. Organization of Nervous Tissue Nerve Cell Communication Nerve cells are excitable. The resting membrane potential can change in response to a stimuli. In nerve cells, this change is a means by which the cell communicates with other cells. The changes in membrane potential that nerve cells use to communicate with other cells are called action potentials Gated Membrane Channels The stimuli that cause action potentials activate gated channels which are closed until opened by specific signals.