Biology Grade 11
2nd Trimster
Name:
Class:
Date:
Chapter3: section 3 Human Genome
Learning objectives:
1- What are the components of human genome?
2- How the forensic scientists use DNA fingerprinting?
3- How can information from the human genome be used to treat human diseases?
The Human genome completed in 2003.
1) It is:
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2) The purpose of the project is:
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Sequencing the genome:
The scientists organized the nucleotides in the human genome, in order to determine one continuous
human genome sequence.
3) What observation did scientists find after they identified the sequence of the entire human
genome?...................................................................................................................................................
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4) What does human genome sequencing mean?
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5) What is noncoding sequence?
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DNA fingerprinting: The long stretches of noncoding regions of DNA are unique for every individual.
6) What are the use of DNA fingerprinting?
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7) Imagine that you a lunch bag was left on the bus and you had to use DNA fingerprinting to
identify the owner of the lunch bag. The lunch bag had a strand of hair, a finger nail, or an
eyelash on it. What procedure you will follow? Write the steps.
Identifying genes: once the genome has been sequenced, the next step is to identify the genes and determine
their functions, there are many of them still unknown.
Scientists use techniques that integrate computer analysis and recombinant DNA technology to determine
the function of these genes.
8) In Bacteria and Yeasts how researchers identify their genes?
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9) Explain what is bioinformatic?
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10) What do you about DNA Microarrays?
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11) Write the DNA microarrays steps:
The Genome and Genetic Disorders: More than 99% of all nucleotide base sequences are exactly the same
in all human, some times there are various are linked to human diseases.
12) What is Single Nucleotide Polymorphisms?
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13) Explain the HapMap Project?
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14) How do haplotype relate to chromosomes?
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15) Pharmacogenomics is:
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16) What is the benefits of it?
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17) How could gene therapy help to cure a genetic disorder?
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Genomic and proteomics:
18) Genomics is :…………………………………………..
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19) The Proteomics is : ……………………………………
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20) From the figure: where does the genetic information stored? …………………………………
21) What the gene will have expressed in the cell?
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22) What types of future disease treatment will be provided by Proteomics?
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