Tuesday, January 10 Unit 5: DNA, RNA and Protein 2.2 DNA Structure & Function Notes nucleic acids central dogma of biology Organism ● All living organisms contain Cell ● ___________ ● Eukaryotic organisms are made of _________ cells ● Prokaryotic organisms are made of ______ cell ● All cells contain ________________ except reproductive cells (______ and ______) ● Eukaryotic organisms store DNA inside the ___________ of cells Double Helix ● ● The nucleus _____________ DNA from being _____________________ _________________ ● DNA in prokaryotic organisms is __________________, which means it is _____________ DNA is a very _________ molecule To save space inside tiny cells, DNA is stored in the form of a ● DNA contains ______ strands that are organized in _______________ directions Base Pairs ● The bases form _____________________ ○ ____ bonds with ____ ○ ____ bonds with ____ Nucleotide ● DNA is made up of repeating units called ____________________ ● A single nucleotide contains ____ parts ★ The order of DNA bases provides the code for building ________________ ● ★ The order of DNA bases produces ______________________ within organisms (human to human) and between organisms (human to tree) ● The ________ and ________________ form the backbone of the DNA strands The part of the DNA nucleotide that bonds together are called ___________________ ● The bases are connected in the middle by ____________ bonds Structure of DNA Practice #1 __ 1. DNA is made up of repeating monomers called _________________________ __ 2. The function of DNA is to store _________________________ __ 3. The shape of DNA is called a _________________________ __ 4. In eukaryotic cells, like animals, DNA is stored inside the _________________________ __ 5. In prokaryotic cells, like bacteria, DNA is _________________________ __ 6. The bases that are purines are ___________________ and ___________________ __ 7. The bases that are pyrimidines are ___________________ and ___________________ __ 8. How many carbon rings do purines have? ____ How many carbon rings do pyrimidines have? ____ __ 9. The 3 parts of a nucleotide are called ___________, _________________ and ___________________________ __ 10. The type of bonds that connect the two DNA strands are called _________________ bonds __ 11. Which part of a nucleotide bonds together to connect the 2 DNA strands? _______________________________ __ 12. What are the DNA base pairs? (use letters) ___ bonds with ___ / ___ bonds with ___ __ 13. What does DNA provide instructions for building? _____________________ __ 14. Create your own DNA sequence using the 4 DNA letters below: ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ __ 15. The part of the DNA nucleotide that is being sequenced is the ________________________________ Base Pairs- _________________________________________________ Practice #2 Label the following diagram. Use “S” for sugar and “P” for phosphate. Use the first letter of each DNA base. Practice #3 Fill in the strand of DNA by writing the base pair that belongs with each DNA letter Count the number of each letter for the entire DNA molecule in the example above: A T C G Finish this sentence: “The number of A in DNA is always ____________ to the number of T, and the number of G is always ____________ to the number of C.” DNA Sequencing is ______________________________________________________ ☆ If a DNA strand contains 20% adenine, what percent of the bases would be thymine? ______________________________________________________________________ like this: ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ● ● The entire human genome is _______________________ base pairs DNA sequencing can be used in _____________________, _____________________, _____________________, _____________________, & _____________________ Circle ONE nucleotide in the image above ☆ On the same DNA strand that contains 20% adenine, what percent of the bases would be guanine?