Uploaded by tableveggeroot

Note Jan 9 2023

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1320130 Week I
Office hours
Mon 12 30 1 30 RW206C
Intro to Cells
basic organizational unit of life
all
organisms
areone or more cell which arise from preexistingcells
Prokaryotic Cell
h
single celled but ran cohabitate
s
iii
s single celled
live in harsh odd planes
it
OR multicellular
N
has membranebound
no membranebound organelles
smaller than eukaryotes
organelles
larger more iomplex
Origins of Mitochondria
prokaryotes existed
first v1 bit years later
Endosymbiont Theory
0.0.8
loss of
move
terrane
mm
membrane
y
oxygenincreasing
beneficial forbis
00
mitochondria w
doublemembrane
d
symbiotic Relationship
protection
can reproduce
makefood
photosynthetic bacteria
entered thesameway
becoming chloroplasts
happened
t
laterbecells with
chloroplasts havehavesigns
of mitochondria
Evidence for Endosymbiont Hypothesis
1
Mitochondria chloroplasts
have remnants of
their own genomes geneticsystems that look
like modern prokaryotes
2 Both Kept protein synthesis components these
resemble prokaryotes
too
sensitive
3 fossil record
4
Information Flow
RNA
DNA
doublemembrane around organelles different
from cell
membrane
Protein
translation
transcription
not all DNA transcribed
DNA
LENI
rRNA
part
d
mRNA
translation
I
Protein
of
transport AA
catalyze protein
protein synthesis they
all DNARNAprotein cell has
at one time
Proteininteractions
e'x.mg
characteristics
jt
tasttyllleicithan
Nucleotide
in cell
of cell
DNA RNA proteins are linear chains of into with polarity
Nucleic Acids
protein
DNARNA cell's geneticmaterial
different ends
1
Pentose
Bases
sugar
scaffold forbase
2
Nitrogenous base
varies
3
Phosphate group
backbone
IP ZP'sSP's
DNARNA
RNA
Mt
differences
Ribose
e
v c T Pyrimidine
see pthinepyramids
919
Purethings are good
Acid Nomenclature
GLAU
Deoxyribose
go
NucleicAcidChains
hosphodiester
bond
BASE t SUGAR
NUCLEOSIDE
BASE
PHOSPHATE
SUGAR
DNA synthesized from dNTPs
RNA synthesized from NTP
NUCLEOTIDE
Molecular Interaitions
2 Eleitrostatic attractions
z
ionic bonds
H bonds
3 Van der Waals attraitions
4 Hydrophobic force
individually weak
but ran come together to bond molecules
Double Stranded DNA
base
Jen bonds
sugar
Hydrophobic interactions
van der Waals attractions
Double Helix Structure
energetically favourable
proteins recognizemakecontact
with specific DNA
grooves
Separating DNA strands
sequences
in
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