d
y26
SN2
41111OH
PBrg
f
ff
Yes Br
whom
N
1 Tsa
Py
2 winters Isa
Egaa.se
g
Yat Br
Y
t
E
A
il E
Nu
F Nantz
E A
Good LG
stabilize 0
resonance
charge
polarizability
able to lose
charge
Thermodynamically favorable
Good
T EN
No
the worse the Nu
more polarizable tho buttontho
able to lose
a
NU
0 charge
T steric hindrance INV
rtomforearmmm
q
Snl
racemic mixture
Polar Protic solvent
CAD
F TOH Meat
30 20 carbocation needed
work No
No
Rsp
LG
SNZ
investors
No
LG
t
of stereocenter
Polar apnotio
solvent
No Rsp3
7
LI
backside
oft
DMSO acetone
DME
10120 carbon
ins
Not
strong Nu
minimal stereohindrance
Rsp3 LG
El
B
It
CF Hao
Ek
5 20 carbocation needed
dyI
LG
trans
F2
LG
trans alkene favored most sub alkene
weak base
t
Rsp3 t
Nu
B
r
It
Ija
t
LG
same
1
d
E or Z
alleenu depending on orbital alignment
strong baseGpkazio 00A
go
AnI
t
most sub it
0
Need anti alignment between LG and A
H
1 46
H B t RA t IG
least sub if
t
H
59
R Lo it
LG
t
AB
B is small
B is large
r
e
dyLo
weak No
strong
Nu
weak 13
weak B
Mcort
Cl0 pore I 0
Retort
RF
Azo
e
strong B
strong B
OH
e
RSA
Tko Nrg
CEN
No N
weak No
Me Et
FRg
0
strong Nu
if R is small
0
N N
0
12
7
00
N
0
f
In 4
1
g
NAH
good for
deprotonating
ROH
weak No
carbon
E
RA
weak B
Nu
weak B
strong Nu
weak No
strong B
strong B
spz
N R
LG
NR
SNZ
LG
Nin
SN2
Svz
SMILE
SNz
EZ SNZ
A
4I
strong
LG
E 2
SNI LEI
NR
IZZ
LG
N.TL
SN2
SN2
LG
SN
EZ
F2
0
R
RYN
LG
SNI
SN
SNI SNZ
SNZ
SNZ
N R
NR
NR