Human Anatomy and Physiology © 2012 Pearson Education, Inc. Anatomy is the study of the _______ of the body, while physiology is the study of its ______ . The study of large body structures is called _______anatomy . The study of a body area such as the foot is called ________anatomy The study of an organ system's structure is called ______anatomy. The study of the relationship between internal structure and surface features of the body is called _________anatomy. is the study of small body structures, often too small to be seen with the naked eye ________________________________________________ ________ is the study of tissues, and ______is the study of cells The study of changes in the body's structure over time is called__________ anatomy: a specialized sub-field that deals with such changes prior to birth is called _________. One common way to organize physiological knowledge is to classify it by ____________ An organ is made of several types of _______ The __________system forms the external body covering The _________system protects and supports body organs The _______system houses the blood-forming cells of the body The _______system allows us to move objects in the environment, as well as to move our own bodies. The________system is a major source of heat (allowing us to maintain body temperature The _______system is the fastest-acting control system of the body, activating muscles and glands as needed Organs of the _________system secrete chemicals called hormones into the blood The________system regulates processes such as growth, reproduction, and nutrient use The __________system transports oxygen, carbon dioxide, nutrients, and wastes throughout the body, in the blood. The _________system picks up fluid "leaked" from the blood vessels and returns it to the blood. The_________system attacks foreign substances within the body The__________system keeps blood supplied with oxygen and disposes of unwanted carbon dioxide. The ________system breaks food down into chemicals which can enter the blood for distribution to the body's cells The ________system disposes of items which have been eaten, but which lack nutrient value The system eliminates excess nitrogen from the body The system produces sperm or eggs and sex hormones. The _________system regulates water and electrolyte levels and (to some extent) the pH of the blood Organisms that ingest other organisms must these items to capture energy and raw materials _________ refers to the entire set of chemical reactions which occur within an organism __________ refers to chemical reactions which lead to the production of complex molecules or structures within an organism. __________ refers to chemical reactions which degrade or destroy complex molecules or structures within an organism in order to capture energy or raw materials Life must dispose of unneeded items, which is done is a process called ________ When a constant, dynamic equilibrium is maintained despite changes in the environment (for example, our ability to maintain a constant body temperature), this is called _________ The knees are _____________to the ankles The spine is ________ to the breastbone The eyes are _______ to the bridge of the nose The nose is _______ to the mouth The mouth is _______ to the forehead The genitals are ______ to the hips ''Acromial'' refers to the ____________ ''Antecubital'' refers to the _____________ Chapter 1 The Human Body: An Orientation The Human Body—An Orientation Anatomy •Studies the structure of body parts and their relationships. Physiology •Study of how the body and its parts work or function Pathophysiology •Study of functional changes associated with disease and aging. Anatomy—Levels of Study Gross or Macroscopic anatomy •Larger structures •Can be seen with the naked eye •Approached of study: Regional and Systemic Anatomy Anatomy—Levels of Study Surface anatomy •Study of internal structures as they relate to the overlying skin surface. Anatomy—Levels of Study Microscopic anatomy •Structures cannot be seen with the naked eye •Structures can only be viewed with a microscope •Subdivisions include cytology and histology Anatomy—Levels of Study Developmental anatomy •Traces structural changes that occur in the body throughout the life span. •Embryology – concerns developmental changes that occur before birth. The Language of Anatomy •Special terminology is used to prevent misunderstanding •Exact terms are used for •Position •Direction •Regions •Structures • prone position - anatomical position is placed face-down • supine position- anatomical position is placed face-up • posterosuperior view combines the posterior and superior • B) anterosuperior Regional Terms • Anterior body landmarks Cephalic Frontal Orbital Nasal Buccal Oral Mental Cervical Thoracic Sternal Axillary Upper limb Acromial Deltoid Brachial (arm) Antecubital Antebrachial (forearm) Abdominal Umbilical Pelvic Inguinal (groin) Carpal (wrist) Manus (hand) Digital Lower limb Coxal (hip) Femoral (thigh) Patellar Pubic (genital) Crural (leg) KEY: Fibular Pedal (foot) Tarsal (ankle) Thorax Abdomen Back (Dorsum) Digital (a) Anterior/Ventral Figure 1.5a Regional Terms • Posterior body landmarks Cephalic Occipital (back of head) Upper limb Acromial Cervical Brachial (arm) Back (dorsal) Scapular Olecranal Antebrachial (forearm) Vertebral Lumbar Manus (hand) Digital Sacral Gluteal Lower limb Femoral (thigh) Popliteal Sural (calf) Fibular KEY: Thorax Pedal (foot) Calcaneal Abdomen Back (Dorsum) Plantar (b) Posterior/Dorsal Figure 1.5b Directional Terms •Superior (cranial or cephalad) toward the head end or upper part of a structure or the body; above •Inferior (caudal) away from the head end or toward the lower part of a structure the body; below Directional Terms •Ventral (anterior) toward or at the front of the body; in front of •Dorsal (posterior) toward or at the backside of the body; behind Directional Terms •Medial: toward or at the midline of the body; on the inner side of •Lateral: away from the midline of the body; on the outer side of the body •Intermediate: between a more medial and a more lateral structure Directional Terms •Proximal: close to the origin of the body part or point of attachment to a limb to the body trunk •Distal: farther from the origin of a body part or the point of attachment of a limb to the body trunk Directional Terms •Superficial: toward or at the body surface •Deep: away from the body surface; more internal •Ipsilateral: on the same side •Contralateral: opposite side © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. (a) Median (midsagittal) Vertebral column Rectum © 2012 Pearson Education, Inc. Intestines (b) Frontal (coronal) plane Right lung Liver Heart Left lung Stomach Spleen (c) Transverse plane Liver Aorta Spinal cord Spleen Subcutaneous Stomach fat layer Figure 1.6 Naming Structures of the Body PREFIX MEANING EXAMPLE abdomin/o abdomen Peritoneal acr/o extremity Acromegaly aden/o gland Adenoma angi/o vessel Angiogram arthr/o joint Arthritis cardi/o heart chondr/o cartilage cyst/o bladder Cystitis cyt/o cell cytology den/o tooth dermat/o skin derm/o skin duoden/o duodenum © 2012 Pearson Education,Inc. Naming Structures of the Body PREFIX MEANING EXAMPLE gastro stomach Gastritis hepat/o liver Hepatitis / Hepatoma laryng/o larynx Laryngitis my/o muscle Myology/Myositis nephr/o kidney Nephritis neur/o nerve Neurology oste/o bone Osteoporosis ot/o ear Otitis path/o disease Pathologic Anatomy rhin/o nose Rhinitis / Rhinoplasty stomat/o mouth Stomatitis thorac/o Thorax (chest) Pleural © 2012 Pearson Education,Inc. Body Cavities •Dorsal body cavity •Cranial cavity houses the brain •Spinal cavity houses the spinal cord •Ventral body cavity •Thoracic cavity houses heart, lungs, and others •Abdominopelvic cavity houses digestive system and most urinary system organs © 2012 Pearson Education,Inc. Body cavities (and organs found within them): •Dorsal Cranial cavity - within the rigid skull, contains the brain. Spinal cavity - which runs within the bony vertebral column, protects the spinal cord. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. Body cavities (and organs found within them): •Ventral •Thoracic cavity • Pleural cavity • Mediastinum • Pericardial cavity •Abdominopelvic cavity • Abdominal cavity - stomach - intestines - liver, etc. • Pelvic cavity © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. Ventral Body Cavity Membranes •Called serous membranes or serosa •Parietal serosa lines internal body walls •Visceral serosa covers the internal organs •Serous fluid separates the serosae © 2012 Pearson Education,Inc. Heart Serosae © 2012 Pearson Education,Inc. Figure 1.10b Serous Membrane Relationship © 2012 Pearson Education,Inc. Figure 1.10a Abdominopelvic quadrants (and organs found in each region): •Right upper •Right lower •Left upper •Left lower © 2012 Pearson Education,Inc. Nine abdominopelvic regions (and organs in each regions): • Right hypochondriac • Epigastric • Left hypochondriac • Right lumbar • Umbilical • Left lumbar • Right iliac (inguinal) • Hypogastric • Left iliac (inguinal) © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. Other Body Cavities •Oral and digestive cavities •Nasal Cavity •Orbital cavities •Middle ear cavities •Synovial cavities © 2012 Pearson Education,Inc. Molecules Smooth muscle cell 2 Cellular level Cells are made up of molecules. Atoms 1 Chemical level Atoms combine to form molecules. 3 Tissue level Tissues consist of similar types of cells. Smooth muscle tissue Blood vessels Heart Epithelial tissue Smooth muscle tissue Blood vessel (organ) Cardio– vascular system Connective tissue 4 Organ level Organs are made up of different types of tissues. 5 Organ systemlevel Organ systems consist of different organs that work together closely. Levels of Structural © 2012 Pearson Education, Inc. 6 Organismal level Human organisms are made up of many organ systems. Figure 1.1 © 2012 Pearson Education,Inc. Figure 1.1, step 2 © 2012 Pearson Education,Inc. Figure 1.1, step 3 © 2012 Pearson Education,Inc. Figure 1.1, step 4 © 2012 Pearson Education,Inc. Figure 1.1, step 5 © 2012 Pearson Education,Inc. Figure 1.1, step 6 Organ System Overview •Integumentary •Protects deeper organs from injury due to bumps, chemicals, bacteria, and dehydration. •Excretes salts and urea •Helps regulate body temperature •Produces vitamin D © 2012 Pearson Education,Inc. • Components • Skin • Nails • Hair • Cutaneous sense organs and glands Organ System Overview •SKELETAL al •Protects and supports intern organs •Provides levers for muscular action •Cavities provide a site of blood cell formation •Stores minerals • Components • Bones • Cartilage • Tendons • Ligaments © 2012 Pearson Education,Inc. Organ System Overview •Muscular •Produces movement •Maintains posture •Produces heat © 2012 Pearson Education,Inc. Organ System Overview •Nervous •Fast-acting control system •Responds to internal and external change •Activates muscles and glands •Helps maintain short-term homeostasis of the body via rapid transmission of electrical signals © 2012 Pearson Education,Inc. Organ System Overview •Endocrine system •Secretes chemical molecules, called hormones, into the blood •Body functions controlled by hormones include: •Growth •Reproduction •Use of nutrients •Plays a role in regulating long-term homeostasis © 2012 Pearson Education,Inc. Organ System Overview •Cardiovascular •Transports materials in body via blood pumped by heart •Oxygen •Carbon dioxide •Nutrients •Wastes © 2012 Pearson Education,Inc. Organ System Overview •Lymphatic •Returns fluids to blood vessels •Cleanses the blood •Involved in immunity © 2012 Pearson Education,Inc. Organ System Overview •Respiratory •Keeps blood supplied with oxygen •Removes carbon dioxide •Contributes to the acidbase balance of the blood © 2012 Pearson Education,Inc. Organ System Overview •Digestive •Breaks down food •Allows for nutrient absorption into blood •Eliminates indigestible material as feces © 2012 Pearson Education,Inc. Organ System Overview •Urinary •Eliminates nitrogenous wastes •Maintains acid-base balance •Regulates water and electrolytes © 2012 Pearson Education,Inc. Organ System Overview •Reproductive •Produces offspring •Testes produce sperm and male hormone •Ovaries produce eggs and female hormones © 2012 Pearson Education,Inc. © 2012 Pearson Education,Inc. Necessary Life Functions •Maintain boundaries •Internal environment remains distinct from the external environment •Movement •Locomotion •Movement of substances •Responsiveness or excitability •Ability to sense changes and react •Digestion •Breakdown and absorption of nutrients © 2012 Pearson Education,Inc. Necessary Life Functions •Metabolism—chemical reactions within the body •Break down complex molecules into smaller ones •Build larger molecules from smaller ones •Produces energy •Regulated by hormones •Excretion •Eliminates waste from metabolic reactions •Wastes may be removed in urine or feces © 2012 Pearson Education,Inc. Necessary Life Functions •Reproduction •Occurs on cellular level or organismal level •Produces future generation •Growth •Increases cell size and number of cells © 2012 Pearson Education,Inc. Survival Needs •Nutrients •Chemicals for energy and cell building •Includes carbohydrates, proteins, lipids, vitamins, and minerals •Oxygen •Required for chemical reactions © 2012 Pearson Education,Inc. Survival Needs •Water •60 to 80 percent of body weight •Most abundant chemical in the human body •Provides for metabolic reaction •Stable body temperature •37°C (98°F) •Atmospheric pressure •Must be appropriate for gas exchange © 2012 Pearson Education,Inc. Maintaining Homeostasis •The body communicates through neural and hormonal control systems © 2012 Pearson Education,Inc. Homeostasis •Homeostasis—maintenance of relatively stable internal conditions •A dynamic state of equilibrium, or balance •Necessary for normal body functioning and to sustain life •Homeostatic imbalance •A disturbance in homeostasis results in disease © 2012 Pearson Education,Inc. 3 Input: Information sent along afferent pathway to control center. 2 Receptor Receptor Control Center Afferent pathway Efferent pathway sent along efferent pathway to effector. Effector 5 Response detects change. 1 Stimulus produces change in variable. 4 Output: Information VARIABLE (in homeostasis) © 2012 Pearson Education,Inc. of effector feeds back to reduce the effect of stimulus and returns variable to homeostatic level. Figure 1.4 1 Stimulus produces change in variable. VARIABLE (in homeostasis) © 2012 Pearson Education,Inc. Figure 1.4, step1 •Receptor •Responds to changes in the environment (stimuli) 2 Receptor detects change. Receptor •Sends information to control center 1 Stimulus produces change in variable. VARIABLE (in homeostasis) © 2012 Pearson Education,Inc. Figure 1.4, step2 3 Input: Information sent along afferent pathway to control center. 2 Receptor Receptor Control Center Afferent pathway detects change. 1 Stimulus produces change in variable. VARIABLE (in homeostasis) © 2012 Pearson Education,Inc. •Control center •Determines set point •Analyzes information •Determines appropriate response Figure 1.4, step3 3 Input: Information sent along afferent pathway to control center. 2 Receptor Receptor Control Center Afferent pathway Efferent pathway 4 Output: Information sent along efferent pathway to effector. Effector detects change. 1 Stimulus produces change in variable. VARIABLE (in homeostasis) © 2012 Pearson Education,Inc. •Effector •Provides a means for response to the stimulus Figure 1.4, step4 3 Input: Information sent along afferent pathway to control center. 2 Receptor Receptor Control Center Afferent pathway Efferent pathway sent along efferent pathway to effector. Effector 5 Response detects change. 1 Stimulus produces change in variable. 4 Output: Information VARIABLE (in homeostasis) © 2012 Pearson Education,Inc. of effector feeds back to reduce the effect of stimulus and returns variable to homeostatic level. Figure 1.4, step5 Feedback Mechanisms •Negative feedback •Includes most homeostatic control mechanisms •Shuts off the original stimulus, or reduces its intensity •Works like a household thermostat © 2012 Pearson Education,Inc. Feedback Mechanisms •Positive feedback •Increases the original stimulus to push the variable farther •In the body this only occurs in blood clotting and during the birth of a baby © 2012 Pearson Education,Inc. Homeostatic imbalance + • SEROSITIS – inflammation of the serous membrane 3 TYPES: • Pericarditis – inflammation of pericardium (heart) •Pleuritis – also pleurisy - inflammation of pleura (lungs) •Peritonitis – peritoneum © 2012 Pearson Education,Inc.