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Posology
Pharmacy (Rajiv Gandhi University of Health Sciences)
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alassmate
Dato
Pag
PosoLOGY
cocoosos mtaunS.
His derived: trom Greek
losdloay 13.dene
nomuch aaad logy aaeamg Scence'
oitk how
Po
raloa
(
science
AA abranch
drug
much oammunl
Ho be odnmanisteed
ortuthe
quantity A
the enzyme
childten
n
Mendt ena
dg
is
in the lbddyi
Atechhg the dbse
tacto
Age
ich deaks
in. the livert
developeoli
exceretian temaioless
So
nd
al
he
odult.
dose should be less than at
In caae aelderly patient,he reual dunctim
decline_anl
dug
nmetabäliamn
the
Iiverr als6 decrceaaesy
abseptiombecomeslouoerto
aiveaAministee
yety
AAoarpiO.
e
have to
less close
DAisHilhon
M Metalb ism
Excrethm
.female
Sexln cane" s treatnaent oth sex hoxmsme
buks ttquires',mallete dosage an: male due
moce bddy ta.
othe Poesence
pecio
carte daould be toke
åhle administeriug
any
ag to a ooman h
duug menstutcaio n,
pepnaneyamd lactatim,stmna purgative vhould
nðl
beqenduitina tthose time
Anhesnalnut a
pat jalkalaiels. should nát be taken
dudng poeginants do avrid deloxaiooi
doefus.
ol
edative
alaoiuld
noi
be.
'faken
AntikiStaane
dauuglackatisa becayse these_are
ewownefo autor
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Dote
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Bady soeakl he usual dosageo
mentionès
dugs
tor to Kg adultk
ne dag conentrahionai sie
actionk
boaed a the ra hoa. betoen the amout
Sdg adminstered and the sae 4 the
bbdy
The do0se caleulation or abntrmall y tin
ortobesty airtsan.ate_reaureo
nhe
to caltulate
baaisd by eigd
bodi suace area Many pyúdlogytctor
Such aa plosmaGdlume
Oxugen Conauphiom.
Owmd rteauurcemed bádyiaelectrites
Calpresnod gloterater gloneda
Hrahon ane propohisnal to the une
ExAnH cartruert daas ie mefiotrexate
Odm nisterned acmidiug to thebidy stase
9eyerity6 diseaaeH ig commg Hhat duul.
eadache mau be reheued by a ug le able
pirunuöher as
severe headache nos
seauive adinistraim 2-3 talylets
Roudeadsinighralhon n general,1he rapidkobsotuptim.d dng decd eaae aum.tate
nsavenbus Intramaculba) subeiisncoue
dral- 2.Sag
Jtrawmoalos-lng
ntsayentunsDSug
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Aime aolunistaten.e dngs ar most qwcly
alosokedom eehystomach
2
deloy
atomoch
hepreaenceoo
in he
OsDptim
betoe
Hence a pölent: dag gien
'mea
daug
AntttrHent
du igdiluteddit
2iven a{ter mol
nd
ad
20
pvduce
leK
ciniom
xnuency
adag8
dKq adnunstzationr islogical kalt lie
hat i the timereequiteedort blod level
ad
to
dsop doon to SO
the in'hal_ peok level in he
ain actort ot govercninge
reuency dr2
odiistxatiad,
2xt lslogicad ballide a sulphoclia2ineis 4 hout
1gm-ddmg haa to be taken
tadose
evettyA hout after
2aro
notcyatentd
0 Physiholgaical8tate a nd
Pyehologicallae
tecd #he rexporaeo1
dn
com
n
Nerves_armd anxlous pahend stequures ambte
enerta
anoesfhetics
Placebo io an inef 8.dhatance, tat _does ns Contain
dmg
Commomly
used placeoose are lactose taklefs and
digilkd' watet.
XSllerome
SOme cidaen
Onge doses a
seraace
eva Con tölertade
relathd
ssenit,belladma, etc
an be aqwred aa a resudt cepeaBed
odnainastsalion
coned
2n mornpane,héroin, tocone
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elass
Date
Page
multounedus adrumeration-2ot
moedng
Aoddutiom The combineacHioo
Sum .
uo0
da is uad o someindivudual ettet.
exol
1+1 2
bupaiin tpoaacetamd1eAnalgchei
ynertgimThey
ettect pMduced s greatt
U,
founthe atuthmetickum
De
t0o dmugs
An
4=>2
codelngt Aspireinmode taom Aualgeha
Antagonsm
A
ontet
substasté thai gBops tve aatian.
sie
EXonplt
ekiecl aand
suk kthanee
Aptibictamines dacka AisthminesAy)t
Accomulatisn Amy dug ill _accumulate in
2-bod e
ale Aaksapion IS mefto
he tatt eliminaion
0n
eliminattd druo ae. aAen oltumulatd
iM he õdy er
ampáuse toMiciky
&x
Polouaedt
chvoguneeasile
lanas EAto eetoine, etE
tehua
kbeyncho onmd Hypert3engitivihs
Sd iosn chrosy tISim
tatep.Honal
toodrtug ine tdidiual pohtn. teanse
EMamle n sme pat
oapin_haaucae
sOAséagtiaomapemllin:icilis aauie
rti tat
Rnhes mHe h.
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clasSMAte
Date
Page
Hpertseneativity
4, ia an advertse eeet Renctid=
CctuRg due tochemical reaction tesultig aompme vidus exposurtR, to the substante, 0CCuAig
n
wy in a nall rac kim all pesple
etee Reaeiu he
pooti.cula drgTCclag
Yediatic dose calculatign
NomoamMefhod
t is
ußed to delertmine he
cotreecpaedia peeliatncmedicatin.dosage
bovaed 0
body Sutace aria
hld dose = Cwld béd BSA in meBet X
Adult des
118
larks Rule
Child dse ol qclild los) y Adulidese
YOs RuleCuk dese-Age.a chid.Chs)xA
Age. l2
trend rule
A
so
YoU
-AduHda6
cld dase -Aae.ocld (Mantia
AY-
Alult doK
ISQ
XAduutHtgt
Aose t1L2
ATY o
620
eloraloo
0-
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alass
12/2
AsSTGNMENT-04.
HARMICEUTICAL CALCULATION
Deinatian
Metcic Sysiem-Most a he courties,use
he meic.
Systemdhich usesméaauringwnit 3uchaameterto,
ams, Kiloyaam,mílliaxan8,cemimelerta
Inpetial ayslem-In Hhe inided 3tales pecple oise
iperial 3ystem,here things ate meaauted
the aldert
in ee,-
inchesounces poulpds,yaadga
lable metruc length
1 kilometerKm)
l600 melernt
1hectometert(hm) l6D metert
1 decámeterr(dam)E10melerei
meterre
1melere i
ylii2
1deimelertdrn) Ol60etert
lcendimetestAcm)s 0.0l0metet
1 millimeiereéom)EO00Lmeter
1micrtocmelert(Am)EO.OITN meler
1nanometet mm)OAKCO,GOO,cO1.
quidelineg
ore 0tivng aot
use aS1 ustem.
*LInt ames and umbal genernaldyate n
Loritfeo
1ocapidal letee:excep henldree used a ihe
beginnig
a gerndence ort ieoti heaiding
* Poriod is n
Rnd
used jalloxoing 1synabats ceceplat he
a senence.
apleAmd md Agm
A mpourd u hai is ralio a quaiat ta
wr is indicaled by a älidus C) Sndh_ed Snd h
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elAs
Date
Page
Smb
should not he combine spela
Ou fermS in ihe 3ame exprecsan.
aBmnm
Furals a uii names uhen spelled out
have an addeds)Sumb61 kort un hoee
duRe fhe same in giuguuanand plural
exopleSmlliteeg nat ShLL
Dedma mctoo are used nt Common
tm bion exanaple S.25g.m nd# SagmPercentagePreepaaation
The percenlageconceotzahiaoachive
and inactive constiRted in vasious ty pes
phogmaceulitalpaeposationane defmed
tlons by the uP
ferecendoge_oeighdinwalunnelW/y)Aexprees the numbere
oms consdituei in1nl
liquid prepacation.
sötution.ar
Yerce.ntage dlumen võlume
V
express fhe number millime
tera a conetitue n l0D
uhon or
lquid pteparcaHon.
L Pecceotagevoeight in ieigbdCiws)
O expees the number a
cowatituend in lDgm dpreacah.
so
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Date
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Ohat is allegahion
and give dne example
allegation method 2
Ais an arhmelical methad 4saving posblems1ha
nvslves the mirig the salutionore mixtute o
Salids poasessingelete
pertcenioge strength
Allegation méthad pablem
hat
n
pooportion shoud alcshs 9SZ and S0Z
Stnength be mixed
to
make
0/._alc hal
20/
204 95Z and-257 q SD
4'S ratio
eite
the toxmula tor spired caladahonsreezig
pai
methodand i NaCl euivalent methodi
socalclate e
rumbereapr
allon akttlated
cordained in a gienauaztiky olushsl a specikeel
501
Exausple : Houd many pusigallon
arte in 3 ine galam
4
P
allon
SXIS
u5
SD
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Fage
FreeRing pain method
Ihe
.
yreeezing paind
bdy{uid
bd
is-.s2heprepaaah
addihxes.
ainngdaugand
eual deeiung
Teeczig
blood ad dhere
point
paint raethol
Teezing peint
li
mu3t kave
2ii
kddfhid
reezig poi a dug sål.al
Distialart Stoengtä
tonioity adjul
(veeag poi
Calculate
Ao make
sádium La7,dred
the ámawd
SK dextanse sdlutton isdtow
0.S2
0,4SS
Sodiumchloide euialend method
Equivaleat method aNaclL
Maluooi Nad
iact
a the 3ubsor
acioraNaiMslidt slsubshamë.
baioo
tdpoxte
elCaleudade the Xsodiiy chloide equivalentjo
alycercine,o ropelectre+luieolth molecular i
1217acor.
5R
92
8.2.5X 0-01
O82S.2 2EX
oli
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