ASSIGNMENT COVER SHEET Please complete all areas of this form, sign, and attach to each submitted assignment. Submit each assignment according to the instructions provided in your Course Outline. A. STUDENT/S TO COMPLETE Program Name: BOSHE Student ID Number:20222069 Postal/ Email Address: allanmvula99@gmail.com Course Name: INTRODUCTION TO EPIDEMIOLOGY Student Names:ALLAN MVULA Phone Number: 0979277447 Assignment Number:1 Lecturer Name: Date Due:25/11/2022 Date Submitted:24/11/22 Declaration I declare that this assessment item is my own work, except where acknowledged, and has not been submitted for academic credit elsewhere, and acknowledge that the assessor of this item may, for the purpose of assessing this item: Reproduce this assessment item and provide a copy to another member of the University and/or; Communicate a copy of this assessment item to the University for Marking I certify that I have read and understood the University Rules in respect of Student Academic Misconduct. Student Signature:Allan mvula Date:21/11/2022 B. MARKER TO COMPLETE Mark/Grade Lecturer’s Comments 1 a) Define epidemiology. Epidemiology is the study of the distribution and determinants of health-related states or events in human populations and the application of this study to th prevention and control of health problems. b)Explain the role of epidemiology in public health practice and individual decision making. the following are the roles of epidemiology in public health practices and individual decision making. epidemiologists can track disease and predict its future outcomes. Identifying risk factors for disease, injury,and death Identifying where the public health problem is greatest Monitoring diseases and other healthrelated events over time Evaluating the efficacy and effectiveness of prevention and treatment programs Providing information that is useful in health planning and decision making for establishing health programs with appropriate prioritie Communicating public health information interdependence of these activities is evident Describing the natural history of disease 2,i.List some of the contributions of the microscope to epidemiology Microscopes have opened up many doors in science. By using Microscopes scientists, researchers and students were able to discover the existence of microorganisms, study the structure of cells and see the smallest parts of plants, animals and fungi.When it comes to biology, Microscopes are important because biology mainly deals with the study of cells (and their contents), genes and all organisms. Some organisms are so small that they can only be seen by using magnifications of 40x-1000x, which can only be achieved with the use of a microscope. Cells are too small to be seen with the naked eye.Microscopes are not just used to observe cells and their structure but are also used in many industries. For example, electron microscopes help create and observe extremely tiny electrical circuits found on Silicon microchips. Scanning microscopes are much more sophisticated and they have higher magnifications than light-refracting microscopes.Apart from biological research use and industrial use, Microscopes are also used in the field of genetics. Genetics is the study of variations in an organism generation after generation. Genetic engineering requires the mixing of genes. Genes are even smaller than cells, which is why microscopes are essential in this field.Without the microscope, mankind would not have been so developed and many diseases would still have no cure. ii.A)James Linda. CLINICAL TRIALJames Lind (4 October 1716 - 13 July 1794) was a Scottish physician. He was a pioneer of naval hygiene in the Royal Navy. By conducting the first ever clinical trial, he developed the theory that citrus fruits cured scurvy. His work advanced the practice of preventive medicine and improved nutrition.In 1747, Lind did a trial on 12 sailors, the results of which showed the effectiveness of a mix of lemon and orange juices against scurvy.However, the experiment occupies only four out of 400 pages of his treatise on scurvy, in several chapters of which he disregards the observations. Scurvy, Lind writes, is provoked mainly by dampness. Adding, in the chapter on prevention, that those affected need dry air. Lind recommends lemon juice only to fight the effects of the dampness inevitable at sea. Furthermore, the chapter on treatment hardly mentions citrus fruit, and instead focuses on exercise and change of air. Lemons are mentioned, but Lind adds that they can be replaced by an infusion.In the third edition of his dissertation,published after 14 years of treating patients with scurvy, Lind is still unable to confirm the efficacy of lemons. He begins his treatise with an admission of defeat: “Remedies more absolutely certain, might perhaps have been expected.” Also, in the postscript, he states: “This strict abstinence from the fruits of the earth was continued long enough to convince me that the disease would often take a favourable turn, which cannot be ascribed to any diet, medicine, or regimen whatever.”5 years later, the physician confirms his opinion that lemon is not particularly effective in treating seamen with scurvy,suggesting that, if lemon juice is unavailable, tartaric acid should be used. To credit Lind with the discovery of lemon juice as a treatment against scurvy therefore seems erroneous B)Doll and Hill. COHORT STUDY he early findings from Doll's group, which clearly identified smoking as a human carcinogen, had a large influence in the great decline in the prevalence of cigarette smoking, which took place in the United Kingdom since the 1950s, and in the United States and many other countries shortly thereafter . This has undoubtedly postponed many deaths in the United Kingdom and in many other parts of the world and has led to millions of men (and women) having several years of increased life expectancy. While such a contribution from any one research group is outstanding, that this group has made major contributions in other major disease areas including radiation and cancer, asbestos and other occupational carcinogens, oral contraceptives and disease, treatment of early breast cancer, immediate treatment of myocardial infarction and aspirin and myocardial infarction is unique and remarkable.Unsurprisingly, Sir Richard Doll and Sir Richard Peto have received many awards and widespread recognition for their contribution to public health. Such recognition is well deserved even though such statisticsbased contributions may well be undervalued . Apart from DA Henderson (who directed the World Health Organization's global smallpox eradication campaign (1966–1977) and helped to initiate WHO's global programme of immunisation in 1974), it is difficult to identify a greater contribution to public health in recent times. They really made a difference 3 A) Discuss how infectious and non-infectious diseases relate to communicable and noncommunicable diseases and conditions. Diseases are frequently referred to as communicable or non-communicable. Communicable diseases comprise infectious diseases such as tuberculosis and measles, while noncommunicable diseases (NCDs) are mostly chronic diseases such as cardiovascular diseases, cancers, and diabetes.Epidemics of communicable diseases follow predictable patterns, spreading across vulnerable population sectors by disease carrying agents or vectors. That leads to the term communicable. But recently many people have challenged the use of the term noncommunicable and said that these diseases are actually also communicable.How can chronic non-infectious diseases like cardiovascular diseases be communicable? The answer lies in the causation of chronic diseases. Health risk behaviours such as smoking, unbalanced nutrition, physical inactivity, and excess alcohol use are directly implicated as causal factors for chronic diseases— but the determinants of these risk taking behaviours are too frequently overlooked. These determinants should be considered as vectors for disease that are underpinned by the psycho-social, cultural, ethnic, and socioeconomic attributes of populations, society, and local communities. So the reasons why people undertake health risk behaviours need to be understood in targeting public health interventions.Modern society promotes rapid marketing of new behaviours across populations. This is easily understood when considering marketing of fashion clothing; social “vectors” including peer groups and societal conformity are used to great effect to change behaviours.The determinants of risk taking behaviours are also rooted in society where people seek to copy behaviours promoted as desirable (for example, access to fast food), where peer groups attract the vulnerable (for example, smoking and alcohol consumption), where society promotes certain behaviours (for example, physical inactivity), and where low socioeconomic status restricts healthy lifestyle choices B)List the three general sources of infectious diseases and provide examples Bacteria. These one-cell organisms are responsible for illnesses such as strep throat, urinary tract infections and tuberculosis. Viruses. Even smaller than bacteria, viruses cause a multitude of diseases ranging from the common cold to AIDS. Fungi. Eye Infections and neoformans Infection Parasites. 4. Determine the range, mode, lower quartile, median and mean of the below: 1, 3,3,5,8,10,7,3 and 14. i)Range:13 ii)mode:3 iii)lower quartile:2 iv)median:5 v)mean:6