MEDICATION INFORMATION FORM
Medication: Brand ___Zithromax, Zmax, AzaSite__ Generic ___azithromycin___
Classification: __Anti-infective__
Pharmacologic ___Macrolide___
Mechanism of Action: binds to 50S ribosomal subunits of
susceptible bacteria to control various bacterial infections;
more effective in gram-negative organisms
Medication Administration (onset/peak/duration if applicable):
PO
IV
Onset
Rapid
Rapid
Peak
2-4 hours
End of infusion
Duration
24hr
24hr
Dose Ordered: 500mg/day for 3 days Safe Dose Range:5002000mg daily
Indication for this patient:
Campylobacter infection
Antidote:____unknown__________________
Contraindications/Precautions:
Nursing Implications
Hypersensitivity to azithromycin, jaundice,
hepatitis, pregnancy, breastfeeding, sunlight
exposure, colitis, ulcerative colitis, sodium
restriction
Priority Assessment Pre Administration:
Interactions: digoxin, phenytoin, triazolam,
nelfinavir, methadone, pimozide, triazolam
Monitor respiratory status, renal and liver function and monitor for
CDAD
Monitor allergies, C&S and pregnancy test
Priority Assessment Post Administration:
Assessment of Side / ADVERSE Effects:
Side / ADVERSE Effects:
Seizures
Dizziness

Assess for serious skin reactions
QT prolongation
Fatigue

Assess for super infection
Hepatotoxicity
Vertigo

Assess for C.Diff
Cholestatic jaundice
Nausea

Leukopenia
Rash
Monitor respiratory status for rate, wheezing, tightness in
chest
Angioedema
Photosensitivity
Evaluation of Effectiveness for
this patient:
Protein C and Protein S
negative for infection
WBC within normal limits
(5,000 – 10,000)
Patient Education (What would you tell the patient?):
-
Notify physician of diarrhea stools, dark urine, pale stool, yellow
discoloration of eyes or skin or severe abdominal pain
Notify provider if suspect pregnancy
Teach to take 1 hour before meal or two hours after
Don’t take aluminum or magnesium containing antiacids with this
medication
Complete regimen even if symptoms gets better