Morgan LaRose Group: 204 E September 11, 2022 IV DISCUSSION QUESTIONS Directions: Please complete the discussion questions on this sheet before the IV Lab and bring the completed form to the IV Lab. Incomplete forms will be evaluated as Inadequate clinical preparation. 1. Describe the comprehensive role of the nurse in administration of IV Fluids/Medications. Nurses have an important role in the preparation and administration of IV solutions such as 0.9% sodium chloride (normal saline, [NS]), 0.45% sodium chloride (½NS), 5% dextrose in water (D5W), and Lactated Ringer’s solution (LR) and IV compatible medications. The nursing functions and responsibilities during IV administration include the following: Assess patient for manifestations of fluid and electrolyte imbalances. Determine if ordered IV therapies are appropriate. Choose and insert appropriate IV catheters and infusion devices. Give IV fluids and medications. Monitor for adverse reactions to IV fluids or medications. Assess for manifestations of fluid overload or hypovolemia and initiate appropriate changes in IV fluids. Evaluate if IV therapies are addressing patient’s fluid and electrolyte needs. Collaborate with the pharmacist to: • Determine appropriateness of IV therapies and need for dose adjustments. • Prepare IV infusions and medications. • Screen for potential problems, such as compatibility issues. • Monitor response to therapy. 2. Describe common reasons for administration of intravenous fluids and intravenous medications. Patients are often unable to maintain normal fluid balance because of disease, surgery, or trauma. As a result, it is common to replace needed fluids directly into the bloodstream through IV administration. IV fluids are considered medications and are given with the same caution and rights used for medication administration. There are several advantages to using the IV route. It provides immediate access for fluid and electrolyte maintenance or replacement; medications given intravenously have a much faster onset and more predictable effect. The IV route provides access for supplemental or total nutrition replacement and allows transfusion of blood and blood products to increase oxygen-carrying capacity and reestablish normal oncotic pressure. 1020 IV Lab Fall 2019 rev. 8/28/19 Page 1 of 6 3. Differentiate between a continuous infusion and an intermittent infusion. State reasons for each type of infusion. Continuous Infusion: (0.9% saline solution, Insulin drip) flow continuously until the container of solution is changed or the order for the infusion is stopped. Continuous IV infusion replaces fluid loss, maintains fluid balance, and serves as a vehicle for IV drugs. Intermittent Infusion: (IV piggyback [IVPB]) contain a larger volume of diluent and are administered over a longer period (e.g., 30 minutes, 1 hour, 3 hours). This type of infusion is used when continuous IV infusion is to be discontinued but the patient still requires IV access. 4. There are different types of Venous/Vascular Access Devices (VAD). Differentiate between the following types: Peripheral catheter: Peripheral sites are used when IV therapy will be short term or intermittent or to maintain vascular access with the use of an intermittent infusion device. IV catheters come in several types and sizes. IV catheters are sized by the diameter of the needles (gauge) The smaller the diameter, the larger is the gauge. The nurse selects the smallest size needed for IV therapy. The three basic types of peripheral access catheters are: Over-the needle catheter (ONC) or Angiocath, Winged infusion needle (butterfly needle), and Midline catheters Midline catheter: Used for longer-term IV therapy inserted by specially trained nurses through a peripheral vein using ultrasound guidance. Catheter is 3 to 8 inches long Inserted in the antecubital area, with the tip resting in the cephalic or basilic vein, right below the axilla. Considered inside-the-needle catheters, the catheter remains inside the needle or introducer during insertion. After the catheter is threaded through the vein, the needle is removed. Midlines are used when IV therapy is expected for less than 2 weeks. Midlines last longer and have lower rates of phlebitis than short peripheral catheters Have higher rates of non–life-threatening complications compared to PICC lines careful consideration should be made based on individual patient needs Peripherally inserted central catheter (PICCs): Very common in patients requiring long-term IV therapy Inserted in a vein in the arm and has lower rates of complications compared to other types of CVCs. inserted by a specially trained nurse can be left in indefinitely as long as there are no complications. 1020 IV Lab Fall 2019 rev. 8/28/19 Page 2 of 6 inserted in the cephalic or basilic vein or antecubital space and threaded up until it rests in the superior vena cava outside the right atrium. Strict sterile technique is used during insertion and maintenance care of PICC lines to prevent central-line associated bloodstream infection (CLABSI). The PICC device often has multiple lumens and can simultaneously infuse incompatible medications, fluid, blood, or total parenteral nutrition (TPN). Require regular assessment, flushing, and sterile dressing changes per facility policy. Ideal devices for patients who require long-term antibiotics, or other medications, especially patients who have a history of failed or difficult IV access with short peripheral catheters. Nurse must advocate to the provider if he or she thinks the patient might benefit from a PICC line. Nontunneled central venous catheter Used in patients who require short-term but extensive IV therapy (e.g., multiple IV medications), TPN, or recurring blood transfusions. The CVC is inserted by the physician, usually at the bedside, using the subclavian vein. (Avoid using the jugular and femoral veins because of the higher incidence of catheter-related infections) often have double or triple lumens, allowing for simultaneous administration of incompatible medications, fluids, and TPN. They are designed for short-term therapy (days to weeks) associated with a high risk for complications, including catheter-related infections, pneumothorax, and pulmonary embolism. Tunneled Central Venous Catheter: Used for lifelong or long-term IV therapy such as TPN, chemotherapy, and dialysis use. Inserted into the subclavian or jugular vein and then pulled through (i.e., tunneled) the subcutaneous tissue in the chest wall before exiting the skin. initially sutured into place have a cuff that the subcutaneous tissue eventually adheres to, holding the catheter in proper position. Implanted Port: AKA Medi Port surgically placed in the chest wall and can be used for long-term IV therapy that is continuous or intermittent (e.g., chemotherapy, hemophilia, sickle cell disease) A tunneled CVC is attached to a port or access device that has been implanted into the subcutaneous tissue in the chest wall, leaving no visible signs of the device. To access the site for IV infusions, the nurse inserts an angled or Huber needle through the skin and into the port. After the infusion is complete, the needle is removed, leaving a closed system. Implanted ports have the lowest incidence of catheter-related infections. 1020 IV Lab Fall 2019 rev. 8/28/19 Page 3 of 6 An implanted port should be accessed at least monthly to ensure patency with either a heparin or saline flush. 5. What is the purpose of using “Y-type Tubing” for administration of blood products? Most blood product administration tubing is of a “Y type” with a macroaggregate filter (170 to 260 microns; filters out particulate). One arm of the Y is for the isotonic saline solution and the other arm of the Y for the blood product. This tubing permits the infusion of 0.9% sodium chloride before and after each blood component and for the dilution of RBC that are too viscous to be transfused at the appropriate rate. 6. Describe Total Parenteral Nutrition (TPN) and include indications for the use of TPN. Total parenteral nutrition (TPN) is a hypertonic IV solution designed to meet a patient's total nutritional needs. contains amino acids, glucose, lipids, vitamins, minerals, electrolytes, and trace elements. TPN provides the calories, protein building blocks, and fluid needed to promote wound healing and meet metabolic requirements used when the patient is unable to meet nutritional and metabolic demands through oral intake or when disease (e.g., pancreatitis, ulcerative colitis, bowel obstruction) or surgery requires complete bowel rest. Indications for TPN include: debilitating illnesses lasting longer than 2 weeks loss of more than 10% of pre-illness weight serum albumin levels less than 3.5 g/dL nitrogen loss due to extensive burns or draining wounds. 7. What is the formula for calculating an IV flow rate in mL/h? 8. What is the formula for calculating an IV flow rate in mL/h when the infusion time is less than 60 minutes? 9. What is the formula for calculating an IV flow rate in gtt/min? 1020 IV Lab Fall 2019 rev. 8/28/19 Page 4 of 6 10. Complete the table below by describing isotonic, hypotonic and hypertonic solutions. IV Solutions and Osmolarity Crystalloid: Isotonic Solution Hypotonic Solution Hypertonic Solution Osmolarity Physiologic effect Indications SAME approximate osmolality as ECF or plasma. Exerts LESS osmotic pressure than ECF, which allows water to move into the cell Exerts GREATER osmotic pressure than ECF, resulting in higher solute concentration than the serum "Osmotic equilibrium" water does not enter or leave the cell; therefore, there is no effect on red blood cells (RBCs). Isotonic solutions are primarily used for hydration and to expand ECF volume, because the fluid remains in the intravascular space. LR provides electrolytes and is used for rehydration in all types of dehydration and FVD. Results in an increased solute concentration in the intravascular space, causing fluid to move into the intracellular and interstitial spaces Pulls water from the interstitial space to the ECF via osmosis and causes cell shrinkage 1020 IV Lab Fall 2019 Replaces cellular fluid by treating intracellular dehydration (diabetic ketoacidosis, hyperosmolar hyperglycemic state) Provides free water to allow excretion of body wastes Dextrose provides some calories rev. 8/28/19 Increases serum osmolality Corrects severe hyponatremia Decreases ICP in patients with cerebral edema Dextrose provides some calories Higher concentrations of dextrose (>10%) must be given through a central venous access device; may be added to amino acid solutions as total parenteral nutrition. Page 5 of 6 Examples of IV Solution LR (lactated ringers) 0.9% NaCl (normal saline//NS) 5% Dextrose in water (D5W) 0.45% NaCl (1/2 NS) 0.33% NaCl (1/3 NS) 0.225% NaCl (1/4 NS) 3% NaCl 5% NaCl 5% Dextrose in 0.45% NaCl 5% Dextrose and 0.9% NaCl 5% Dextrose in LR 10% Dextrose in Water (D10W) 11. Complete the table below by describing complications of IV therapy. Complication Catheter related infection (local or systemic): Local infection that occurs at insertion site, if not recognized, can become systemic (septicemia) and possibly life-threatening; usually caused by poor aseptic technique during inserting or dressing or tubing changes; can occur when peripheral site has been in use for longer than 4 days. Assessment Findings Local symptoms: Pain at site, tenderness, erythema (redness), swelling, increased temperature, purulent drainage Systemic symptoms: Fever, chills, tachycardia, hypotension, complaints of headache, backache Prevention: Use aseptic technique during insertion and site care. Rotate sites per agency protocol or when clinically indicated. Assess site frequently for signs of infection. Tenderness, redness, swelling at site Pain, burning, heat along the vein, especially during infusion Palpable venous cord Phlebitis: Inflammation of the vein caused by poor insertion and care technique, frequent manipulation of IV catheter, size and length of the catheter, use of Scale to grade severity: 0: No symptoms 1020 IV Lab Fall 2019 Nursing Action DISCONTINUE peripheral IV, and restart in another location. Place used catheter in sterile container and send to laboratory for culture and sensitivity testing. Notify PCP of findings. Replace old IV tubing and solution with new. Do not discontinue a CVC without a physician's order. rev. 8/28/19 DISCONTINUE catheter IMMEDIATELY (if infection suspected) send catheter tip for culture and sensitivity testing. Clean insertion site with disinfectant. Page 6 of 6 irritating medications or fluids, and infection Infiltration: Infusion of IV solution and/or nonvesicant medications into surrounding tissues, caused by puncturing of the blood vessel through improper insertion or frequent manipulation of IV catheter 1: Redness at site with or without pain 2: Pain with erythema 3: All the above plus red streak along vein and palpable venous cord 4: All the above plus purulent drainage Swelling, tenderness, coolness, and firmness of extremity; blanching of skin. Scale to grade severity: 0: No symptoms 1: Skin blanched, edema <1 inch, cool to touch, may have pain 2: All the above plus edema of 1 to 6 inches 3: All the above plus extremity translucent, edema >6 inches, mild to moderate pain, possible numbness 4: All the above plus tight, leaking skin, deep pitting edema, circulatory impairment, moderate to severe pain (typically considered extravasation) Apply warm moist compresses for 20 min three or four times per day. When inserting new IV catheter, use opposite extremity if possible. Prevention: use smallest gauge possible (22 or 24 gauge) stabilize catheter securely to minimize movement rotate sites according to agency policy or when clinically indicated. DISCONTINUE infusion and remove catheter. Apply pressure at site to stop bleeding. Apply warm compresses to increase circulation for isotonic or hypotonic fluids. Apply cold for infiltration of hyperosmolar fluids. Outline the area of visible damage with a marker to assess changes. If leaking of tissues occurs, cover area with sterile dressing until leaking subsides. Report grade 3 or 4 infiltrations to PCP. Use opposite extremity when inserting new IV catheter. Prevention: Assess for signs of infiltration at least q2h Extravasation: Inadvertent infusion of vesicant (causing blisters, 1020 IV Lab Fall 2019 Similar to infiltration Burning and discomfort Blistering is a late sign rev. 8/28/19 DISCONTINUE INFUSION IMMEDIATELY Page 7 of 6 ulceration, sloughing) or irritating solution or medication into surrounding tissues. This can lead to permanent tissue damage and/or nerve damage. Notify PCP and obtain orders for extravasation treatment and/or antidote. Use a skin marker to outline area of visible damage to assess changes. Cautious use of cold or warm compresses and elevate the extremity. Never apply pressure to the area. Use opposite extremity when inserting new IV. Prevention: Know which medications are considered vesicants, including dopamine, norepinephrine, high concentrations of electrolytes, and several antibiotics. Vesicant and irritating solutions or medications should be infused slowly and through a larger vein or CVC. Fluid Overload and pulmonary edema: Occurs when the volume infused is greater than the cardiovascular system can tolerate; can lead to heart failure, shock, and cardiac arrest Early signs: Restlessness, gradual increase in heart rate, headache, dyspnea, nonproductive cough Late signs: Hypertension, severe dyspnea, gurgling respirations, productive cough of frothy sputum, crackles in lung bases, increased jugular vein distention provide bed rest in high Fowler position slow infusion rate to keep vein open notify PCP immediately provide oxygen as needed administer diuretics and pain medications as ordered. Prevention: slower infusions for patients with underlying heart or renal disease Monitor for early signs and symptoms of fluid excess. Use an electronic infusion device for patients at risk, such as those with cardiac disease history or the elderly. Measure daily weights, intake, and output. 1020 IV Lab Fall 2019 rev. 8/28/19 Page 8 of 6 Speed Shock: Systemic reaction when medication is administered too quickly Sudden onset of dizziness facial flushing headache irregular heart rate during medication administration Frequently assess IV infusion and ensure it is not infusing too rapidly. STOP INFUSION IMMEDIATELY maintain IV access with IV solution that does not contain medication notify PCP immediately and monitor vital signs. Prevention: Follow recommended infusion rate for medication. Monitor gravity-flow sets closely during medication administration. Use electronic infusion devices whenever possible for medication administration. Air Embolism: Accidental entry of air into bloodstream due to improper preparation of IV tubing or loose connections Chest pain shoulder or low back pain dyspnea cyanosis hypotension tachycardia syncope decreased level of consciousness place patient in Trendelenburg position on left side. Locate the source of air and close off. Notify PCP immediately. Administer oxygen as needed. Have emergency resuscitation equipment available. 12. Describe techniques that are used to prevent air embolism during IV tubing set changes. Ensure that catheter and tubing are clamped closed when changing tubing. Use Luer-Lok connections on all tubing. 1020 IV Lab Fall 2019 rev. 8/28/19 Page 9 of 6 Prime all tubing with IV solution before attaching to catheter. Follow agency protocol when removing a CVC. If IV bag has run dry, inspect tubing closely for air. 13. Order: Vancomycin 0.5 g IVPB q.6h. Pt has a continuous IV infusion of D5NS with 40 mEq of potassium chloride running at 125 mL/h Supply: Vancomycin 500 mg vial (powder) You will need to use a nursing drug guide to answer the following questions. Use either the Davis’s Drug Guide for Nurses (available online using the CCRI Library in the Nursing Reference Center, the Gahart’s Intravenous Medications book (a recommended resource for N 1020) or a nursing drug reference book of your own. a. What solution and amount (of solution) will you use to reconstitute this medication? b. Will the D5NS & the potassium chloride be compatible with Vancomycin at the Y-site? c. In order to prepare this medication for infusion as a piggyback (secondary infusion), what IV solution and what amount (size of IV secondary/mini bag) will you utilize? d. What is the suggested rate for this intermittent infusion 14. Review the IV Bolus (Push) Drugs section on pp. 315-320 in Clinical Nursing Calculations 2nd ed. Practice IV Push Problem Order: Ativan 2 mg IV push Supply: Ativan 4 mg/mL Ativan guidelines indicate the IV infusion should not exceed 2 mg/min. a. Calculate the amount (in mL) of Ativan you should prepare in order to administer the ordered dose b. Use ratio proportion to calculate the time required to administer the drug dosage ordered 1020 IV Lab Fall 2019 rev. 8/28/19 Page 10 of 6 c. Calculate the amount (in mL) you should administer every 15 seconds. 1020 IV Lab Fall 2019 rev. 8/28/19 Page 11 of 6