Generic Name Therapeu c Class Trade Name Pharmacologic Class An lipemics Atorvasta n Lipitor HMG-CoA Reductase inhibitors Furosemide diure cs Lasix Loop diure cs Heparin an coagulants Hep-Lock Isosorbide Mononitrate an thrombo cs An aginal Imdur Nitrate Tamsulosin BPH Drugs Flomax Metoprolol Tartrate Safe Dose Range Onset Peak Dura on Admin Time(s) Mechanism of Ac on Commons Adverse Effects Nursing Considera ons All reasons for med O: Unknown D: 20mg R: PO 10-80mg daily P:1-2hr F: q24 D:Unkno wn 0900 Inhibits HMG-CoA reductase, an early step in cholesterol biosynthesis Insonmia, stroke, rhabdomyolysis, muscle spasms Pt should try diet interven on first, watch for myopathy CAD, stroke preven on, hyperlipidemia 2.5g D: 40mg R: PO F:q24 O: 20-60 P1-2hr D:6-8hr 0900 Inhibits NA & CI reabsorp on from loop of Henle & distaltubule Loss of electrolytes, dehydra on, headache, dizziness, SJS Monitor weight, BP, & pulse rou nely with long-term use Edema, HTN 20000 units/12 hours SQ D: 5000 units R: SQ F: q24 O: Imme P: Imme D: Variable 1300 Poten ates the inhibitory effect of an thrombin on factor Xa & thrombin Excessive bleeding, thrombocytopenia, anemia, rash Monitor platelets count every 3-4 days during therapy DVT or PE. Thromboprophylaxis Thought to reduce cardiac oxygen Demand by decreasing preload and a erload drug Also may increase blood flow through the collateral l receptors in the prostate, Headache dizziness orthosta c hypotension tachycardia nausea vomi ng Monitor blood pressure heart rate intensity and dura on of drug response Angina Monitor for decrease in BP BPH Hold for BP < 90 HR < 60 HTN MI Angina HF Max dose is 160mg D: 30mg R:PO F: q24 O:30-45 min P: 30-60min D:4-8hr 0900 max 0.8mg O: D: 0.8mg R:PO Unknown F: q24 P: 4-7hr D: 9-15hr 0900 Alpha Blockers an hypertensive Ordered Dose / Route / Freq. 400mg ER or D: 150mg R: O: 15min P: 1 hr 0900 leading to relaxa on of Dizzy, headache, chest smooth muscles in the pain, ortho hypotension, bladder neck and nausea, diarrhea, back prostate, improving urine pain flow and reducing Selec ve beta-blocker. Blocks beta1 receptors, decreases cardia output Bradycardia, HF, stroke, fa gue dizziness Lopressor Beta-blockers Spironolactone diure cs Aldactone Potassium Sparing diure cs Levothyroxine Thyroid hormone replacement Levoxyl Acetylsalicylic Acid thyroid Hormones g 450mg IR g PO F: q12 75mg daily D: 17.5mg R: PO F: q24 O:Unkno wn P: 3-4hr D: 2-3days D: 50mcg R: PO F:q24 O:3-5 days P: 2-4 hr D: Unknown 12.5-25 mcg start increase PRN P: 1 hr D: 6-12hr decreases cardia output, peripheral resistance & cardia O2 consump on fa gue, dizziness, headache, hypotension Hold for BP < 90, HR < 60 HTN, MI, Angina, HF 0900 Antagonizes aldosterone in the distal tubules, increasing sodium and water excre on Hyperkalemia, anaphylaxis, thrombocytopenia, headache Increases serum K levels, monitor electrolytes, may effect digoxin level test Edema, HTN, HF 0800 Synthe c form of thyroxine that affects the growth of ssues, energy expenditure, and the turnover of all substrates Insomnia, headache, arrhythmias, cardiac arrest, HF, MI, diarrhea DM II may need increased insulin doses when first started on med, watch for angina and CAD Hypothyroidism, Myxedema Coma, Thyroid hormone replacement GI bleeding, hyperglycemia, nasea, vomi ng, prolonged bleeding, hepa s, arrhythmias Inflammatory condi on, rheuma c fever, and thrombosis. Give on schedule rather than PRN, monitor elderly as they're more suscep ble to toxic effect MI, Stroke, Mild pain, Fever, RA, CABG, DVT preven on HF, ortho hypo, muscle spasms Parkinsons, Drug May worsen psych induced extrepyramidal disorders or drug abuse. symptoms, Influenze monitor renal func on type A virus 2100 NSAID 4000mg Bayer Aspirin Salicylates Amantadine An virals Osmolex Synthe c cyclic primary amines Lorazepam Anxioly cs A van Benzodiazepines O:5-30mi D: 81mg R: PO n P: F: Q12 1-2hr D: 1-4hr MAX daily 322mg D: 100mg R: PO D: q24 O: Unknown P: 2-4hr D: Unknown Max 10mg Daily D: 1-2mg depending on CIWA R: PO or IV F:q4 PRN O:1hr P: 2hr D: 12-24hr 0900 0900 q4 PRN with CIWA score Analgesia, an -inflammatory effect by inhibi ng prostaglandin and other substances that sensi ze pain receptors, fever-hypothalamic temp regula ng center an parkinsonian effect by causing the release of dopamine in the substan a nigra. May prevent release of viral nucleic acid into the host Poten ates the effects of Resp failure, resp GABA, Depresses the depression, hypotension, CNS, and suppresses the seda on spread of seizure ac vity Monitor Hepa c, renal, and hematopie c func on Anxiety, Withdrawal, Insomnia, Pre-op seda on