Uploaded by jen.feely

Diabetes Agents Snapshot

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Diabetes Agents
Parenteral agents
Short duration: rapid acting
Prototype: Insulin lispro (Humalog)
Short duration: short acting
Prototype: Regular insulin (Humulin R)
Intermediate duration
Prototype: Neutral protamine Hagedorn (NPH) insulin
Long duration
Prototype: Insulin glargine (Lantus)
Ultra-Long-acting
Prototype: Insulin glargine (Toujeo)
Mixed Insulin
Prototype: 75% insulin lispro protamine/25% insulin lispro (Humalog Mix 75/25)
Oral agents
Biguanides (make the body do what it does endogenously better)
Metformin (Glucophage)*
Thiazolidinediones (glitazones) (make the body do what it does endogenously better)
Prototype: Pioglitazone (Actos)
Sulfonylureas (pushes insulin out of the pancreas)
Prototype: Glipizide (Gluocotrol)*
Glinides (meglitinides) (pushes insulin out of the pancreas)
Prototype: Repaglinide (Prandin)
SGLT2 (Sodium glucose co-transporter 2) inhibitors (works on kidneys)
Prototype: Canagliflozin (Invokana)
DPP-4 inhibitors (Gliptins) (works on gut hormones)
Prototype: Sitagliptin (Januvia)
Injectable antidiabetic agents
Incretin mimetic (works on gut hormones)
Prototype: Exenatide (Byetta)
Amylin Mimetic (works on gut hormones)
Prototype: Pramlintide (Symlin)
Drugs for hypoglycemia or insulin overdose
Other Endocrine/Metabolism drugs
Prototype: Glucagon
Dextrose IV
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